Strategic white matter hyperintensity locations for cognitive impairment:A multicenter lesion-symptom mapping study in 3525 memory clinic patients

Autor: Mirthe, Coenen, Hugo J, Kuijf, Irene M C, Huenges Wajer, Marco, Duering, Frank J, Wolters, Evan F, Fletcher, Pauline M, Maillard, Frederik, Barkhof, Josephine, Barnes, Thomas, Benke, Jooske M F, Boomsma, Christopher P L H, Chen, Peter, Dal-Bianco, Anna, Dewenter, Christian, Enzinger, Michael, Ewers, Lieza G, Exalto, Nicolai, Franzmeier, Onno, Groeneveld, Saima, Hilal, Edith, Hofer, Dineke L, Koek, Andrea B, Maier, Cheryl R, McCreary, Catarina S, Padilla, Janne M, Papma, Ross W, Paterson, Yolande A L, Pijnenburg, Anna, Rubinski, Reinhold, Schmidt, Jonathan M, Schott, Catherine F, Slattery, Eric E, Smith, Rebecca M E, Steketee, Carole H, Sudre, Esther, van den Berg, Wiesje M, van der Flier, Narayanaswamy, Venketasubramanian, Meike W, Vernooij, Xu, Xin, Charles, DeCarli, Geert Jan, Biessels, J Matthijs, Biesbroek

Publikováno v: Alzheimer's Disease Neuroimaging Initiative 2022, ' Strategic white matter hyperintensity locations for cognitive impairment : A multicenter lesion-symptom mapping study in 3525 memory clinic patients ', Alzheimer's and Dementia . https://doi.org/10.1002/alz.12827
Alzheimer's and Dementia. Elsevier
Alzheimer's & dementia : the journal of the Alzheimer's Association. Elsevier Inc.

INTRODUCTION: Impact of white matter hyperintensities (WMH) on cognition likely depends on lesion location, but a comprehensive map of strategic locations is lacking. We aimed to identify these locations in a large multicenter study.METHODS: Individu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8077889d5ab4f2c124eaa01fa8bd6fd
https://research.vumc.nl/en/publications/e170b6ee-09c5-4778-87eb-3fc4e39a6beb