Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Onkar, M."'
Publikováno v:
Energy Storage (2578-4862); Aug2024, Vol. 6 Issue 5, p1-11, 11p
Akademický článek
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Autor:
Adrian Richter, Ines Rudolph, Ute Möllmann, Kerstin Voigt, Chun-wa Chung, Onkar M. P. Singh, Michael Rees, Alfonso Mendoza-Losana, Robert Bates, Lluís Ballell, Sarah Batt, Natacha Veerapen, Klaus Fütterer, Gurdyal Besra, Peter Imming, Argyrides Argyrou
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Nitro-substituted 1,3-benzothiazinones (nitro-BTZs) are mechanism-based covalent inhibitors of Mycobacterium tuberculosis decaprenylphosphoryl-β-D-ribose-2′-oxidase (DprE1) with strong antimycobacterial properties. We prepared a number of
Externí odkaz:
https://doaj.org/article/6734673c6fd94ca783944bd94b6c5f5b
Autor:
Rab K. Prinjha, Alex Preston, Inma Rioja, Roy Katso, Melanie Leveridge, Chun-wa Chung, Michael David Barker, Laurens Kruidenier, Gerard Joberty, Kevin Lee, Onkar M. P. Singh, Joanna Taylor, Matthew Campbell, Michelle Pemberton, Fiona Brown, Robert Eagle, Carl Haslam, David Matthew Wilson, Neil Stuart Garton, Tracy Jane Shipley, Colin J. Suckling, Philip G. Humphreys, Gerard Drewes, Laurie J. Gordon, Pamela Thomas, Jack A. Brown, Gail A. Seal, Thomas George Christopher Hayhow, Susan Marie Westaway
Publikováno v:
Journal of Medicinal Chemistry. 59:1370-1387
Following the discovery of cell penetrant pyridine-4-carboxylate inhibitors of the KDM4 (JMJD2) and KDM5 (JARID1) families of histone lysine demethylases (e.g., 1), further optimization led to the identification of non-carboxylate inhibitors derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd41f32203668dbba76c4b0b0fbc2e4
https://doi.org/10.1021/acs.jmedchem.5b01538
https://doi.org/10.1021/acs.jmedchem.5b01538
Autor:
Richter, Adrian, Rudolph, Ines, Möllmann, Ute, Voigt, Kerstin, Chung, Chun-wa, Singh, Onkar M. P., Rees, Michael, Mendoza-Losana, Alfonso, Bates, Robert, Ballell, Lluís, Batt, Sarah, Veerapen, Natacha, Fütterer, Klaus, Besra, Gurdyal, Imming, Peter, Argyrou, Argyrides
Publikováno v:
Scientific Reports
'Scientific Reports ', vol: 8, pages: 13473-1-13473-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
'Scientific Reports ', vol: 8, pages: 13473-1-13473-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Nitro-substituted 1,3-benzothiazinones (nitro-BTZs) are mechanism-based covalent inhibitors of Mycobacterium tuberculosis decaprenylphosphoryl-β-D-ribose-2′-oxidase (DprE1) with strong antimycobacterial properties. We prepared a number of oxidized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::30506cde2764e3cf635db892dc56374a
http://europepmc.org/articles/PMC6128881
http://europepmc.org/articles/PMC6128881
Autor:
Shweta Hanumant Ganage, Ashwini Ajit Nikam, Janhavi Sudhir Bhatkar, Onkar M. Marathe, Abhishek Dattaram Ghagare
Publikováno v:
2018 Second International Conference on Inventive Communication and Computational Technologies (ICICCT).
In this paper we introduce IEEE 14 Bus system with heavy electrical vehicle load at the end bus. An analysis is carried out on magnitudes of all the 14 buses with different load parameters using PSAT tool box. Renewable sources are introduced at seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::591faae6c30f3d3be8757adb2d7bd9f4
https://doi.org/10.1109/icicct.2018.8473352
https://doi.org/10.1109/icicct.2018.8473352
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Laurens Kruidenier, Rebecca Randle, Hawa Diallo, Inma Rioja, Clement Douault, Anne Rueger, Chun-wa Chung, Thomas George Christopher Hayhow, Rab K. Prinjha, Alex Preston, Roy Katso, Matthew Campbell, Michael David Barker, J. Mosley, Kevin Lee, Joanna Taylor, Marcel Muelbaier, Douglas W. Thomson, Gail A. Seal, Jack A. Brown, Susan Marie Westaway, Onkar M. P. Singh, Gerard Joberty, Philip G. Humphreys, Melanie Leveridge, Laurie J. Gordon, Pamela Thomas, Carl Haslam, Fiona Brown, John Liddle, Gerard Drewes, Robert Eagle, Robert J. Sheppard, David Matthew Wilson
Publikováno v:
Journal of medicinal chemistry. 59(4)
Optimization of KDM6B (JMJD3) HTS hit 12 led to the identification of 3-((furan-2-ylmethyl)amino)pyridine-4-carboxylic acid 34 and 3-(((3-methylthiophen-2-yl)methyl)amino)pyridine-4-carboxylic acid 39 that are inhibitors of the KDM4 (JMJD2) family of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169f1f983c8269e73c78cea4fff0100e
https://pubmed.ncbi.nlm.nih.gov/26771107
https://pubmed.ncbi.nlm.nih.gov/26771107
Publikováno v:
European Journal of Biochemistry. 5/15/81, Vol. 116 Issue 2, p311-316. 6p.
Autor:
Francisco-Javier Gamo, Onkar M. P. Singh, Maria J. Lafuente-Monasterio, Dyann F. Wirth, Leila S. Ross, Paul Rowland, Roger C. Wiegand
Publikováno v:
The Journal of Biological Chemistry
'Journal of Biological Chemistry ', vol: 289, pages: 17980-17995 (2014)
'Journal of Biological Chemistry ', vol: 289, pages: 17980-17995 (2014)
Background: Inhibiting PfDHODH kills malaria parasites, but the potential for drug resistance is unknown. Results: Selections gave several categories of resistance mutations. Several mutants were hypersensitive to other drugs. Conclusion: Resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76d166f8ab850e7cb81a5af36c0b1a9
https://pubmed.ncbi.nlm.nih.gov/24782313
https://pubmed.ncbi.nlm.nih.gov/24782313