Recombinant human soluble domain of CD39L3 and ticagrelor: cardioprotective effects in experimental myocardial infarction.

Autor: Vilahur G; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain.; Centro de Investigación Biomédica en Red Cardiovascular (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain., Radike M; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain.; Radiology Department, Liverpool Heart and Chest Hospital NHS Foundation Trust, Liverpool, UK., Sutelman P; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain., Ben-Aicha S; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain., Gutiérrez M; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain., Casaní L; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain., Hovdal D; DMPK, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Ongstad EL; Bioscience Cardiovascular, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Gabrielsen A; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Hidalgo A; Radiology Department, Hospital Josep Trueta, Girona, Spain., Fjellström O; Projects, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Carlsson L; Bioscience Cardiovascular, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Badimon L; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain.; Centro de Investigación Biomédica en Red Cardiovascular (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.

Publikováno v: European heart journal [Eur Heart J] 2024 May 07; Vol. 45 (17), pp. 1553-1567.

Association of oxidized ApoB and oxidized ApoA-I with high-risk coronary plaque features in cardiovascular disease.

Autor: Sorokin AV; Section of Inflammation and Cardiometabolic Diseases, Cardiovascular Branch., Hong CG; Section of Inflammation and Cardiometabolic Diseases, Cardiovascular Branch., Aponte AM; Proteomics Core, and., Florida EM; Section of Inflammation and Cardiometabolic Diseases, Cardiovascular Branch., Tang J; Section of Lipoprotein Metabolism, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland, USA., Patel N; Section of Inflammation and Cardiometabolic Diseases, Cardiovascular Branch., Baranova IN; Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, Maryland, USA., Li H; Section of Inflammation and Cardiometabolic Diseases, Cardiovascular Branch., Parel PM; Section of Inflammation and Cardiometabolic Diseases, Cardiovascular Branch., Chen V; Bioinformatics/Integrated Data Sciences Section, Research Technology Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA., Wilson SR; Section of Lipoprotein Metabolism, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland, USA., Ongstad EL; Bioscience Cardiovascular, Research and Early Development, and., Collén A; Projects, Research and Early Development, Cardiovascular, Renal, and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA., Playford MP; Section of Inflammation and Cardiometabolic Diseases, Cardiovascular Branch., Eggerman TL; Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, Maryland, USA., Chen MY; Section of Inflammation and Cardiometabolic Diseases, Cardiovascular Branch., Kotani K; Division of Community and Family Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan., Bocharov AV; Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, Maryland, USA., Remaley AT; Section of Lipoprotein Metabolism, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland, USA.

Publikováno v: JCI insight [JCI Insight] 2023 Oct 23; Vol. 8 (20). Date of Electronic Publication: 2023 Oct 23.

High Plasma Levels of Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 Are Associated With Inflammation and Cardiometabolic Risk Profiles in Pediatric Overweight and Obesity.

Autor: Stinson SE; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark., Jonsson AE; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark., Andersen MK; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark., Lund MAV; The Children's Obesity Clinic, Accredited European Centre for Obesity Management, Department of Pediatrics Holbæk Hospital Holbæk Denmark.; Department of Biomedical Sciences, Faculty of Health and Medical Sciences University of Copenhagen Denmark., Holm LA; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark.; The Children's Obesity Clinic, Accredited European Centre for Obesity Management, Department of Pediatrics Holbæk Hospital Holbæk Denmark., Fonvig CE; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark.; The Children's Obesity Clinic, Accredited European Centre for Obesity Management, Department of Pediatrics Holbæk Hospital Holbæk Denmark.; Department of Pediatrics Kolding Hospital a part of Lillebælt Hospital Kolding Denmark., Huang Y; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark., Stankevič E; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark., Juel HB; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark., Ängquist L; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark., Sørensen TIA; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark.; Department of Public Health, Faculty of Health and Medical Sciences University of Copenhagen Denmark., Ongstad EL; Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD., Gaddipati R; Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD., Grimsby J; Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD.; Regeneron Pharmaceuticals, Inc. Tarrytown NY., Rhodes CJ; Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark., Christiansen M; The Children's Obesity Clinic, Accredited European Centre for Obesity Management, Department of Pediatrics Holbæk Hospital Holbæk Denmark.; Department for Congenital Disorders Statens Serum Institute Copenhagen Denmark., Holm JC; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark.; The Children's Obesity Clinic, Accredited European Centre for Obesity Management, Department of Pediatrics Holbæk Hospital Holbæk Denmark.; Faculty of Health and Medical Sciences University of Copenhagen Denmark., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark.

Publikováno v: Journal of the American Heart Association [J Am Heart Assoc] 2023 Feb 07; Vol. 12 (3), pp. e8145. Date of Electronic Publication: 2023 Jan 25.

MEDI6012: Recombinant Human Lecithin Cholesterol Acyltransferase, High-Density Lipoprotein, and Low-Density Lipoprotein Receptor-Mediated Reverse Cholesterol Transport.

Autor: George RT; Early Clinical Development Research and Early Development Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D AstraZeneca Gaithersburg MD., Abuhatzira L; Early Clinical Development Research and Early Development Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D AstraZeneca Gaithersburg MD., Stoughton SM; Early Clinical Development Research and Early Development Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D AstraZeneca Gaithersburg MD., Karathanasis SK; Bioscience Research and Early Development Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D AstraZeneca Gaithersburg MD., She D; Early CVRM Biometrics Research and Early Development Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D AstraZeneca Gaithersburg MD., Jin C; Integrated Bioanalysis Clinical Pharmacology and Quantitative Pharmacology Clinical Pharmacology & Safety Sciences R&D AstraZeneca South San Francisco CA., Buss NAPS; Cardiovascular, Renal and Metabolism Safety Clinical Pharmacology & Safety Sciences R&D AstraZeneca Gaithersburg MD., Bakker-Arkema R; Tanglewood Clinical Consulting Ann Arbor MI., Ongstad EL; Bioscience Research and Early Development Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D AstraZeneca Gaithersburg MD., Koren M; Jacksonville Center for Clinical Research Jacksonville FL., Hirshberg B; Early Clinical Development Research and Early Development Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D AstraZeneca Gaithersburg MD.

Publikováno v: Journal of the American Heart Association [J Am Heart Assoc] 2021 Jul 06; Vol. 10 (13), pp. e014572. Date of Electronic Publication: 2021 Jun 14.

Targeted drug delivery via caveolae-associated protein PV1 improves lung fibrosis.

Autor: Marchetti GM; Antibody Discovery & Protein Engineering, MedImmune, Gaithersburg, MD, 20878, USA.; Cardiovascular & Metabolic Diseases, MedImmune, Gaithersburg, MD, 20878, USA., Burwell TJ; Respiratory, Inflammation and Autoimmune Diseases, MedImmune, Gaithersburg, MD, 20878, USA., Peterson NC; Translational Sciences, MedImmune, Gaithersburg, MD, 20878, USA., Cann JA; Pathology, MedImmune, Gaithersburg, MD, 20878, USA., Hanna RN; Respiratory, Inflammation and Autoimmune Diseases, MedImmune, Gaithersburg, MD, 20878, USA., Li Q; Antibody Discovery & Protein Engineering, MedImmune, Gaithersburg, MD, 20878, USA., Ongstad EL; Cardiovascular & Metabolic Diseases, MedImmune, Gaithersburg, MD, 20878, USA., Boyd JT; Microbial Sciences, MedImmune, Gaithersburg, MD, 20878, USA., Kennedy MA; Pathology, MedImmune, Gaithersburg, MD, 20878, USA., Zhao W; Pathology, MedImmune, Gaithersburg, MD, 20878, USA., Rickert KW; Antibody Discovery & Protein Engineering, MedImmune, Gaithersburg, MD, 20878, USA., Grimsby JS; Cardiovascular & Metabolic Diseases, MedImmune, Gaithersburg, MD, 20878, USA., Dall'Acqua WF; Antibody Discovery & Protein Engineering, MedImmune, Gaithersburg, MD, 20878, USA., Wu H; Antibody Discovery & Protein Engineering, MedImmune, Gaithersburg, MD, 20878, USA., Tsui P; Antibody Discovery & Protein Engineering, MedImmune, Gaithersburg, MD, 20878, USA., Borrok MJ; Antibody Discovery & Protein Engineering, MedImmune, Gaithersburg, MD, 20878, USA. borrokm@medimmune.com., Gupta R; Cardiovascular & Metabolic Diseases, MedImmune, Gaithersburg, MD, 20878, USA.

Publikováno v: Communications biology [Commun Biol] 2019 Mar 07; Vol. 2, pp. 92. Date of Electronic Publication: 2019 Mar 07 (Print Publication: 2019).