Blood Pressure Targets for Adults with Vasodilatory Shock - An Individual Patient Data Meta-Analysis.

Autor: Angriman F; Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto.; Interdepartmental Division of Critical Care Medicine, University of Toronto.; Department of Medicine, University of Toronto., Momenzade N; Department of Mathematics, Université de Sherbrooke, QC, Canada., Adhikari NKJ; Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto.; Interdepartmental Division of Critical Care Medicine, University of Toronto., Mouncey PR; Clinical Trials Unit, Intensive Care National Audit and Research Centre, London., Asfar P; Service de Médecine Intensive Réanimation, CHU Angers, Angers, France., Yarnell CJ; Interdepartmental Division of Critical Care Medicine, University of Toronto.; Department of Critical Care Medicine, Scarborough Health Network, Toronto., Ong SWX; National Centre for Infectious Diseases, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore.; Institute for Health Policy, Management and Evaluation, University of Toronto., Pinto R; Interdepartmental Division of Critical Care Medicine, University of Toronto., Doidge JC; Intensive Care National Audit and Research Centre, London.; Department of Medical Statistics, London School of Hygiene & Tropical Medicine, London., Shankar-Hari M; Institute for Regeneration and Repair, Centre for Inflammation Research, University of Edinburgh.; Department of Intensive Care Medicine, Royal Infirmary of Edinburgh., Harhay MO; Palliative and Advanced Illness Research (PAIR) Center, University of Pennsylvania, Philadelphia.; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia.; Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia., Masse MH; Research Centre of the Centre Hospitalier Universitaire de Sherbrooke, QC, Canada., Harrison DA; Clinical Trials Unit, Intensive Care National Audit and Research Centre, London., Rowan KM; Clinical Trials Unit, Intensive Care National Audit and Research Centre, London., Li F; Department of Biostatistics, Yale University School of Public Health, New Haven, CT., Carter F; Medicine and Health Sciences Faculty, Université de Sherbrooke, QC, Canada., Camirand-Lemyre F; Department of Mathematics, Université de Sherbrooke, QC, Canada., Lamontagne F; Research Centre of the Centre Hospitalier Universitaire de Sherbrooke, QC, Canada.; Department of Medicine, Université de Sherbrooke, QC, Canada.

Publikováno v: NEJM evidence [NEJM Evid] 2024 Nov 18, pp. EVIDoa2400359. Date of Electronic Publication: 2024 Nov 18.

Association Between Infectious Diseases Consultation and Mortality in Hospitalized Patients With Gram-negative Bloodstream Infection: A Retrospective Population-wide Cohort Study.

Autor: Ong SWX; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.; Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia.; Division of Infectious Diseases, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.; ICES, Toronto, Ontario, Canada., Luo J; ICES, Toronto, Ontario, Canada., Fridman DJ; ICES, Toronto, Ontario, Canada., Lee SM; ICES, Toronto, Ontario, Canada., Johnstone J; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.; Division of Infectious Diseases, Sinai Health, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Schwartz KL; ICES, Toronto, Ontario, Canada.; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.; Public Health Ontario, Toronto, Ontario, Canada.; Li Ka Shing Knowledge Institute, Unity Health Toronto, Toronto, Ontario, Canada., Diong C; ICES, Toronto, Ontario, Canada., Patel SN; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Public Health Ontario, Toronto, Ontario, Canada., MacFadden DR; Division of Infectious Diseases, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Langford BJ; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.; Public Health Ontario, Toronto, Ontario, Canada., Tong SYC; Department of Infectious Diseases, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.; Victorian Infectious Diseases Service, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Brown KA; ICES, Toronto, Ontario, Canada.; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.; Public Health Ontario, Toronto, Ontario, Canada., Daneman N; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.; Division of Infectious Diseases, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.; ICES, Toronto, Ontario, Canada.; Public Health Ontario, Toronto, Ontario, Canada.

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2024 Oct 15; Vol. 79 (4), pp. 855-863.

Variant-Specific IgA Protects Against Omicron Infection.

Autor: Goh YS; A*STAR Infectious Diseases Labs, Agency for Science, Technology and Research, Singapore, Singapore., Fong SW; A*STAR Infectious Diseases Labs, Agency for Science, Technology and Research, Singapore, Singapore., Hor PX; A*STAR Infectious Diseases Labs, Agency for Science, Technology and Research, Singapore, Singapore., Loh CY; A*STAR Infectious Diseases Labs, Agency for Science, Technology and Research, Singapore, Singapore., Wang B; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore., Salleh SNM; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore., Ngoh EZX; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore., Lee RTC; Bioinformatics Institute, Agency for Science, Technology and Research, Singapore, Singapore.; GISAID Global Data Science Initiative, Munich, Germany., Poh XY; National Centre for Infectious Diseases, Singapore, Singapore., Rao S; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore., Chia PY; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Ong SWX; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore., Lee TH; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore., Lim C; National Centre for Infectious Diseases, Singapore, Singapore., Teo J; National Centre for Infectious Diseases, Singapore, Singapore., Pada S; Division of Infectious Diseases, Ng Teng Fong General Hospital, Singapore, Singapore., Sun LJ; Infectious Diseases, Alexandra Hospital, Singapore, Singapore., Ong DLS; National University Polyclinic, Singapore, Singapore., Somani J; Division of Infectious Diseases, Department of Medicine, National University Hospital, National University Health System, Singapore, Singapore., Lee ES; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; National Healthcare Group Polyclinics, Singapore, Singapore., Maurer-Stroh S; A*STAR Infectious Diseases Labs, Agency for Science, Technology and Research, Singapore, Singapore.; Bioinformatics Institute, Agency for Science, Technology and Research, Singapore, Singapore.; GISAID Global Data Science Initiative, Munich, Germany.; National Public Health Laboratory, Singapore, Singapore.; Department of Biological Sciences, National University of Singapore, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Wang CI; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore., Leo YS; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lye DC; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Young BE; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Ng LFP; A*STAR Infectious Diseases Labs, Agency for Science, Technology and Research, Singapore, Singapore.; Health Protection Research Unit in Emerging and Zoonotic Infections, National Institute of Health Research, University of Liverpool, Liverpool, United Kingdom.; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom., Renia L; A*STAR Infectious Diseases Labs, Agency for Science, Technology and Research, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.

Publikováno v: The Journal of infectious diseases [J Infect Dis] 2024 Aug 16; Vol. 230 (2), pp. e287-e291.

Follow-up blood cultures do not reduce mortality in hospitalized patients with Gram-negative bloodstream infection: a retrospective population-wide cohort study.

Autor: Ong SWX; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada; Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia; Division of Infectious Diseases, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; ICES, Toronto, Ontario, Canada. Electronic address: s.ong@mail.utoronto.ca., Luo J; ICES, Toronto, Ontario, Canada., Fridman DJ; ICES, Toronto, Ontario, Canada., Lee SM; ICES, Toronto, Ontario, Canada., Johnstone J; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada; Division of Infectious Diseases, Sinai Health, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Schwartz KL; ICES, Toronto, Ontario, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada; Public Health Ontario, Toronto, Ontario, Canada; St. Joseph's Health Centre, Unity Health Toronto, Toronto, Ontario, Canada., Diong C; ICES, Toronto, Ontario, Canada., Patel SN; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Public Health Ontario, Toronto, Ontario, Canada., MacFadden D; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Langford B; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada; Public Health Ontario, Toronto, Ontario, Canada., Tong SYC; Department of Infectious Diseases, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Victorian Infectious Diseases Service, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Brown KA; ICES, Toronto, Ontario, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada; Public Health Ontario, Toronto, Ontario, Canada., Daneman N; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada; Division of Infectious Diseases, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; ICES, Toronto, Ontario, Canada; Public Health Ontario, Toronto, Ontario, Canada.

Publikováno v: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Clin Microbiol Infect] 2024 Jul; Vol. 30 (7), pp. 890-898. Date of Electronic Publication: 2024 Mar 27.

Choosing the right outcomes in infectious diseases clinical research-putting patients front and centre.

Autor: Ong SWX; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia; Division of Infectious Diseases, Sunnybrook Health Sciences Centre, Toronto, ON, Canada., Patel D; Faculty of Medicine and Health Sciences, McGill University, Montréal, QC, Canada., Reinblatt S; Patient representative, Canada., Tong SYC; Department of Infectious Diseases, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Victorian Infectious Diseases Service, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., Lee TC; Clinical Practice Assessment Unit, McGill University Health Centre, Montréal, QC, Canada; Division of Infectious Diseases, McGill University Health Centre, Montréal, QC, Canada., McDonald EG; Clinical Practice Assessment Unit, McGill University Health Centre, Montréal, QC, Canada; Division of General Internal Medicine, McGill University Health Centre, Montréal, QC, Canada., Daneman N; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; Division of Infectious Diseases, Sunnybrook Health Sciences Centre, Toronto, ON, Canada. Electronic address: nick.daneman@sunnybrook.ca.

Publikováno v: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Clin Microbiol Infect] 2024 Jan; Vol. 30 (1), pp. 10-14. Date of Electronic Publication: 2023 Oct 31.