Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ondrej Stanek"'
Autor:
Giusto D. Badami, Marco P. La Manna, Paola Di Carlo, Ondrej Stanek, Irena Linhartova, Nadia Caccamo, Peter Sebo, Francesco Dieli
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTuberculosis (TB) remains the first cause of death from infection caused by a bacterial pathogen. Chemotherapy does not eradicate Mycobacterium tuberculosis (Mtb) from human lungs, and the pathogen causes a latent tuberculosis infection t
Externí odkaz:
https://doaj.org/article/b97de658564942e5b26be373ff2013cb
Autor:
Nela Klimova, Jana Holubova, Gaia Streparola, Jakub Tomala, Ludmila Brazdilova, Ondrej Stanek, Ladislav Bumba, Peter Sebo
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010577 (2022)
The adenylate cyclase (ACT) and the pertussis (PT) toxins of Bordetella pertussis exert potent immunomodulatory activities that synergize to suppress host defense in the course of whooping cough pathogenesis. We compared the mouse lung infection capa
Externí odkaz:
https://doaj.org/article/881f5b46d1f04874b1279ed1b9cd2ffd
Autor:
Jana Holubova, Ondrej Stanek, Attila Juhasz, Illiassou Hamidou Soumana, Peter Makovicky, Peter Sebo
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010402 (2022)
Pulmonary infections caused by Bordetella pertussis used to be the prime cause of infant mortality in the pre-vaccine era and mouse models of pertussis pneumonia served in characterization of B. pertussis virulence mechanisms. However, the biological
Externí odkaz:
https://doaj.org/article/5061be2846c0463c8a747164e5321cd1
Autor:
Ondrej Stanek, Irena Linhartova, Jana Holubova, Ladislav Bumba, Zdenko Gardian, Anna Malandra, Barbora Bockova, Shihono Teruya, Yasuhiko Horiguchi, Radim Osicka, Peter Sebo
Publikováno v:
Toxins, Vol 12, Iss 9, p 596 (2020)
Pathogenic Bordetella bacteria release a neurotropic dermonecrotic toxin (DNT) that is endocytosed into animal cells and permanently activates the Rho family GTPases by polyamination or deamidation of the glutamine residues in their switch II regions
Externí odkaz:
https://doaj.org/article/98ac1536e9904eb0a2b2fcb22602eb9c
Autor:
Cindy Bernelin-Cottet, Charlotte Deloizy, Ondrej Stanek, Céline Barc, Edwige Bouguyon, Céline Urien, Olivier Boulesteix, Jérémy Pezant, Charles-Adrien Richard, Mohammed Moudjou, Bruno Da Costa, Luc Jouneau, Christophe Chevalier, Claude Leclerc, Peter Sebo, Nicolas Bertho, Isabelle Schwartz-Cornil
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Externí odkaz:
https://doaj.org/article/c0ef98fc46f1421fb35a91e160ea2bac
Publikováno v:
Toxins, Vol 11, Iss 6, p 336 (2019)
Cytolytic leukotoxins of the repeat in toxin (RTX) family are large proteins excreted by gram-negative bacterial pathogens through the type 1 secretion system (T1SS). Due to low yields and poor stability in cultures of the original pathogens, it is u
Externí odkaz:
https://doaj.org/article/1dc05b4503764fa582bcba2113948f1d
Publikováno v:
Journal of Proteome Research. 19:3680-3696
Post-translational modifications of proteins enable swift physiological adaptation of cells to altered growth conditions and stress. Aside from protein phosphorylation, acetylation on e-amino group...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff315f61abbc3f353d571b93ef084774
https://doi.org/10.1021/acs.jproteome.0c00178
https://doi.org/10.1021/acs.jproteome.0c00178
Autor:
Humaira Khaliq, Adriana Osickova, Radovan Fišer, Radim Osicka, Jana Holubova, Anna Sukova, Ondrej Stanek, Peter Sebo, Jiri Masin, David Jurnecka
Publikováno v:
J Biol Chem
In a wide range of organisms, from bacteria to humans, numerous proteins have to be posttranslationally acylated to become biologically active. Bacterial r epeats in t o x in (RTX) cytolysins form a prominent group of proteins that are synthesized as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e3a3b613a1c36f1bf6a7d085427cc6
https://doi.org/10.1074/jbc.ra120.014122
https://doi.org/10.1074/jbc.ra120.014122
Autor:
Radim Osicka, Adriana Osickova, Peter Sebo, David Jurnecka, Attila Juhasz, Jiri Masin, Jana Holubova, Ondrej Stanek
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 11655, p 11655 (2021)
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11655, p 11655 (2021)
Volume 22
Issue 21
The whooping cough agent, Bordetella pertussis, secretes an adenylate cyclase toxin–hemolysin (CyaA, ACT, or AC-Hly) that catalyzes the conversion of intracellular ATP to cAMP and through its signaling annihilates the bactericidal activities of hos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b2bf2e4827ac2427426f6c900bad303
https://pubmed.ncbi.nlm.nih.gov/34769101
https://pubmed.ncbi.nlm.nih.gov/34769101
Autor:
Jana Holubova, Ondrej Stanek, Attila Juhasz, Illiassou Hamidou Soumana, Peter Makovicky, Peter Sebo
Publikováno v:
PLoS pathogens. 18(4)
Pulmonary infections caused by Bordetella pertussis used to be the prime cause of infant mortality in the pre-vaccine era and mouse models of pertussis pneumonia served in characterization of B. pertussis virulence mechanisms. However, the biological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0dfe762f34beb75639068832fa9f292
https://pubmed.ncbi.nlm.nih.gov/35395059
https://pubmed.ncbi.nlm.nih.gov/35395059