Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ondrej Bugos"'
Autor:
Lenka Koklesova, Alena Liskova, Marek Samec, Kevin Zhai, Mariam Abotaleb, Milad Ashrafizadeh, Aranka Brockmueller, Mehdi Shakibaei, Kamil Biringer, Ondrej Bugos, Masoud Najafi, Olga Golubnitschaja, Dietrich Büsselberg, Peter Kubatka
Publikováno v:
Biomolecules, Vol 10, Iss 12, p 1653 (2020)
Metastasis represents a major obstacle in cancer treatment and the leading cause of cancer-related deaths. Therefore, the identification of compounds targeting the multi-step and complex process of metastasis could improve outcomes in the management
Externí odkaz:
https://doaj.org/article/06ab10d59ece4ebe800cbcc3dd0406b0
Autor:
Karin Jasek, Peter Kubatka, Marek Samec, Alena Liskova, Karel Smejkal, Desanka Vybohova, Ondrej Bugos, Kristina Biskupska-Bodova, Tibor Bielik, Pavol Zubor, Jan Danko, Marian Adamkov, Taeg Kyu Kwon, Dietrich Büsselberg
Publikováno v:
Biomolecules, Vol 9, Iss 7, p 289 (2019)
The modulation of the activity of DNA methyltransferases (DNMTs) represents a crucial epigenetic mechanism affecting gene expressions or DNA repair mechanisms in the cells. Aberrant modifications in the function of DNMTs are a fundamental event and p
Externí odkaz:
https://doaj.org/article/119160cd92f84e0dbd1c87c10f3c89a2
Autor:
Luis Rodrigo, Kamil Biringer, Marek Samec, Karel Šmejkal, Martin Caprnda, Dietrich Büsselberg, Mariam Abotaleb, Ondrej Bugos, Dana Blahútová, Marian Adamkov, Samson Mathews Samuel, M Petras, Peter Kubatka, Elizabeth Varghese, Mariusz Adamek, Martin Péč, Lenka Koklesova, Alena Liskova, Peter Kruzliak, Rachele Ciccocioppo
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 146:3079-3096
The formation of new blood vessels from previous ones, angiogenesis, is critical in tissue repair, expansion or remodeling in physiological processes and in various pathologies including cancer. Despite that, the development of anti-angiogenic drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2160e25e3f9a59a30539f28fad7fc1e0
https://doi.org/10.1007/s00432-020-03383-8
https://doi.org/10.1007/s00432-020-03383-8
Autor:
Kevin Zhai, Ondrej Bugos, Miroslava Šudomová, Sherif T. S. Hassan, Olga Golubnitschaja, Raghad Khalid Al-Ishaq, Martin Péč, Kamil Biringer, Frank A. Giordano, Lenka Koklesova, Alena Liskova, Marek Samec, Luciano Saso, Peter Kubatka, Marian Adamkov, Dietrich Büsselberg
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8649, p 8649 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Multi-factorial mitochondrial damage exhibits a “vicious circle” that leads to a progression of mitochondrial dysfunction and multi-organ adverse effects. Mitochondrial impairments (mitochondriopathies) are associated with severe pathologies incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a585696ffc162eefa4052f564ba3731
https://www.mdpi.com/1422-0067/22/16/8649
https://www.mdpi.com/1422-0067/22/16/8649
Autor:
Mehdi Shakibaei, Ondrej Bugos, Masoud Najafi, Kamil Biringer, Milad Ashrafizadeh, Marek Samec, Dietrich Büsselberg, Mariam Abotaleb, Lenka Koklesova, Alena Liskova, Kevin Zhai, Peter Kubatka, Aranka Brockmueller, Olga Golubnitschaja
Publikováno v:
Biomolecules, Vol 10, Iss 1653, p 1653 (2020)
Biomolecules
Biomolecules
Metastasis represents a major obstacle in cancer treatment and the leading cause of cancer-related deaths. Therefore, the identification of compounds targeting the multi-step and complex process of metastasis could improve outcomes in the management
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::154e179f2cf6c42da89a66e4bc75000d
https://www.mdpi.com/2218-273X/10/12/1653
https://www.mdpi.com/2218-273X/10/12/1653
Autor:
Karel Šmejkal, Kristina Biskupska-Bodova, Marian Adamkov, Tibor Bielik, Karin Jasek, Alena Liskova, Pavol Zubor, Peter Kubatka, Dietrich Büsselberg, Taeg Kyu Kwon, Desanka Vybohova, Ondrej Bugos, Jan Danko, Marek Samec
Publikováno v:
Biomolecules, Vol 9, Iss 7, p 289 (2019)
Biomolecules
Biomolecules
The modulation of the activity of DNA methyltransferases (DNMTs) represents a crucial epigenetic mechanism affecting gene expressions or DNA repair mechanisms in the cells. Aberrant modifications in the function of DNMTs are a fundamental event and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eabd968ea78571c6101a110b035e703b
https://www.mdpi.com/2218-273X/9/7/289
https://www.mdpi.com/2218-273X/9/7/289
Autor:
Norbert Zilka, Juraj Kucerak, Petr Novak, Peter Filipcik, Ondrej Bugos, Peter Koson, Michal Novak
Publikováno v:
Neurobiology of Aging. 33:1448-1456
Neurofibrillary degeneration induced by misfolded protein tau is considered to be one of the key pathological hallmarks of Alzheimer's disease (AD). In the present study, we have introduced a novel transgenic rat model expressing a human truncated ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866c18ad38fa4446a6092c358dc24b3e
https://doi.org/10.1016/j.neurobiolaging.2010.10.015
https://doi.org/10.1016/j.neurobiolaging.2010.10.015
Publikováno v:
Journal of Neuroimmunology. 209:16-25
It has been hypothesized that misfolded tau protein could be a mediator of the inflammatory response in human tauopathies. Here we show that neurodegenerative lesions caused by human truncated tau promote inflammatory response manifested by upregulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ccfb2fb7f39f6594decb63e2b07722d
https://doi.org/10.1016/j.jneuroim.2009.01.013
https://doi.org/10.1016/j.jneuroim.2009.01.013
Publikováno v:
Cellular and Molecular Neurobiology. 29:859-869
The rat is a model of choice in biomedical research for over a century. Currently, the rat presents the best "functionally" characterized mammalian model system. Despite this fact, the transgenic rats have lagged behind the transgenic mice as an expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fa676ccd7dc21f0f11e1c9242a2826
https://doi.org/10.1007/s10571-009-9367-5
https://doi.org/10.1007/s10571-009-9367-5
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 7, Iss 1, p 64 (2010)
Journal of Neuroinflammation, Vol 7, Iss 1, p 64 (2010)
Background Numerous epidemiological studies demonstrate that genetic background modifies the onset and the progression of Alzheimer's disease and related neurodegenerative disorders. The efficacious influence of genetic background on the disease path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1058a54246bce770900f7786363943
https://pubmed.ncbi.nlm.nih.gov/20937161
https://pubmed.ncbi.nlm.nih.gov/20937161