Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ondřej Rychecký"'
Autor:
Jakub Petřík, Ondřej Rychecký, Tereza Krejčí, Lucia Becherová, Dan Trunov, Maximilián Prachár, Ondřej Navrátil, Pavel Žvátora, Lukáš Krejčík, Ondřej Dammer, Josef Beránek, Petr Kozlík, Tomáš Křížek, Miroslav Šoóš, Jakub Heřt, Samuele Bissola, Simone Berto, František Štěpánek
Publikováno v:
AAPS PharmSciTech. 23(7)
The present study investigates the physicochemical properties and stability of a novel lipid-based formulation-surfactant-enriched oil marbles containing abiraterone acetate. While the biopharmaceutical performance of this formulation has been report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650917d865d60252c82210401e555b57
https://pubmed.ncbi.nlm.nih.gov/36207549
https://pubmed.ncbi.nlm.nih.gov/36207549
Autor:
Martin Krov, Ondřej Rychecký, Maximilián Prachár, Aleš Zadražil, Rudolf Šrámek, František Štěpánek
Publikováno v:
Powder Technology. 411:117944
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d418c53b497deaad0850205c142a7f3
https://doi.org/10.1016/j.powtec.2022.117944
https://doi.org/10.1016/j.powtec.2022.117944
Autor:
Jaroslava Roušarová, Ondřej Dammer, Tereza Boleslavská, Josef Beranek, Ondřej Slanař, Petr Kozlík, Martin Krov, Pavel Žvátora, Ondřej Rychecký, Jana Hořínková, František Štěpánek, Tomáš Křížek, Pavel Ryšánek, Martin Šíma, Nikolina Kutinová Canová
Publikováno v:
The AAPS journal. 22(6)
Abiraterone acetate has limited bioavailability in the fasted state and exhibits a strong positive food effect. We present a novel formulation concept based on the so-called oil marbles (OMs) and show by in vitro and in vivo experiments that the food
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5f84fafaf949c3edce24dea3849c0f
https://pubmed.ncbi.nlm.nih.gov/32978690
https://pubmed.ncbi.nlm.nih.gov/32978690
Publikováno v:
Chemical Papers. 71:1055-1063
The ability to simulate the 3D structure of a human body is essential to increase the efficiency of drug development. In vivo conditions are significantly different in comparison to in vitro conditions. A standardly used cell monolayer on tissue cult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ba41a3df82f23a03ecf6052c5094592
https://doi.org/10.1007/s11696-016-0026-2
https://doi.org/10.1007/s11696-016-0026-2
Publikováno v:
Journal of pharmaceutical sciences. 108(6)
Many new therapeutic candidates and active pharmaceutical ingredients (APIs) are poorly soluble in an aqueous environment, resulting in their reduced bioavailability. A promising way of enhancing the release of an API and, thus, its bioavailability s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5188a223191200166358d284cdc59b4
https://pubmed.ncbi.nlm.nih.gov/30721711
https://pubmed.ncbi.nlm.nih.gov/30721711