Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Ondřej Hrušák"'
Autor:
Jan Starý, Ondřej Hrušák
Publikováno v:
F1000Research, Vol 5 (2016)
Acute lymphoblastic leukemia (ALL) is the most common malignancy in childhood. Despite enormous improvement of prognosis during the last half century, ALL remains a major cause of childhood cancer-related mortality. During the past decade, whole geno
Externí odkaz:
https://doaj.org/article/1e3ddd56b5d44d9f97de1d99a6199df0
Autor:
Michaela Nováková, Markéta Žaliová, Martina Suková, Marcin Wlodarski, Aleš Janda, Eva Froňková, Vít Campr, Kateřina Lejhancová, Ondřej Zapletal, Dagmar Pospíšilová, Zdeňka Černá, Tomáš Kuhn, Peter Švec, Vendula Pelková, Zuzana Zemanová, Gitte Kerndrup, Marry van den Heuvel-Eibrink, Vincent van der Velden, Charlotte Niemeyer, Tomáš Kalina, Jan Trka, Jan Starý, Ondřej Hrušák, Ester Mejstříková
Publikováno v:
Haematologica, Vol 101, Iss 6 (2016)
GATA-2 deficiency was recently described as common cause of overlapping syndromes of immunodeficiency, lymphedema, familiar myelodysplastic syndrome or acute myeloid leukemia. The aim of our study was to analyze bone marrow and peripheral blood sampl
Externí odkaz:
https://doaj.org/article/b1018ecb74424ae1bb1e55581f1bd0c2
Autor:
Barbora Vakrmanová, Michaela Nováková, Petr Říha, Markéta Žaliová, Eva Froňková, Ester Mejstříková, Jan Starý, Ondřej Hrušák, Lucie Šrámková
Publikováno v:
Pediatric Blood & Cancer. 69
Daratumumab, an anti-CD38 antibody, is used experimentally in the treatment of relapsed acute lymphoblastic leukemia (ALL). We treated five patients suffering from relapsed ALL with daratumumab. Four patients had T ALL, three of whom achieved complet
Autor:
Libuse Lizcova, Eva Prihodova, Lenka Pavlistova, Karla Svobodova, Ester Mejstrikova, Ondrej Hrusak, Pavla Luknarova, Iveta Janotova, Lucie Sramkova, Jan Stary, Zuzana Zemanova
Publikováno v:
Molecular Cytogenetics, Vol 17, Iss 1, Pp 1-10 (2024)
Abstract Background T-cell acute lymphoblastic leukemia (T-ALL) represents a rare and clinically and genetically heterogeneous disease that constitutes 10–15% of newly diagnosed pediatric ALL cases. Despite improved outcomes of these children, the
Externí odkaz:
https://doaj.org/article/dd9bf69a7ebc4b1da84c61d75b2dbb82
Autor:
Adam Klocperk, Marketa Bloomfield, Zuzana Parackova, Ludovic Aillot, Jiri Fremuth, Lumir Sasek, Jan David, Filip Fencl, Aneta Skotnicova, Katerina Rejlova, Martin Magner, Ondrej Hrusak, Anna Sediva
Publikováno v:
Molecular and Cellular Pediatrics, Vol 10, Iss 1, Pp 1-8 (2023)
Abstract Background Multisystem inflammatory syndrome in children associated with COVID-19 (MIS-C) is a late complication of pediatric COVID-19, which follows weeks after the original SARS-CoV-2 infection, regardless of its severity. It is characteri
Externí odkaz:
https://doaj.org/article/f4b3704c1d504e8e8d58f03fbe2f9fa3
Autor:
Jan Starý, Ondřej Hrušák, Ondřej Pelák, Martina Vaskova, Tomas Kalina, Herbert Stadler, Daniel Thurner, Kristian Stanar, Marie-Luise Kiene, Jan Stuchlý, Daniela Kužílková
Publikováno v:
Cytometry Part A. 91:62-72
In mass cytometry, the isolation of pure lymphocytes is very important to obtain reproducible results and to shorten the time spent on data acquisition. To prepare highly purified cell suspensions of peripheral blood lymphocytes for further analysis
Autor:
Barbora Vakrmanova, Ester Mejstrikova, Jakub Jonas, Petr Pavlicek, Marketa Zaliova, Marek Turnovec, Livia Molcanyova, Eva Fronkova, Ondrej Hrusak, Lucie Sramkova
Publikováno v:
EJC Paediatric Oncology, Vol 2, Iss , Pp 100097- (2023)
Externí odkaz:
https://doaj.org/article/f1d3a468adbf424eb4f3915dbbb7214b
Autor:
Renata Formankova, Jan Starý, Ondřej Pelák, Ondřej Hrušák, Petr Hubacek, Petra Keslova, Jan Stuchlý, Petr Sedlacek, Tomas Kalina, L. Krol
Publikováno v:
Cytometry Part B: Clinical Cytometry. 92:380-388
Background Cytomegalovirus (CMV) specific T-cells are known to provide long-term control of CMV reactivation, which is a frequent complication of hematopoietic stem cell transplantation. We have studied 58 pediatric patients after hematopoietic stem
Autor:
Jan Stuchlý, Veronika Kanderová, Marcela Vlková, Ivana Heřmanová, Lucie Slámová, Ondřej Pelák, Eli Taraldsrud, Dalibor Jílek, Pavlína Králíčková, Børre Fevang, Marie Trková, Ondřej Hrušák, Eva Froňková, Anna Šedivá, Jiří Litzman, Tomáš Kalina
Publikováno v:
Scientific Reports
Common variable immunodeficiency (CVID) is a heterogeneous group of diseases. Our aim was to define sub-groups of CVID patients with similar phenotypes and clinical characteristics. Using eight-color flow cytometry, we analyzed both B- and T-cell phe
Autor:
Ester Mejstříková, Martina Vaskova, Vendula Pelkova, Jan Starý, Tomas Kalina, Denisa Petráčková, Jaroslav Weiser, Ondřej Hrušák, Markéta Žaliová, Martin Kovac
Publikováno v:
European Cytokine Network. 25:8-13
Acute lymphoblastic leukemia (ALL) cells depend on the microenvironment of the host in vivo and do not survive in in vitro culture. Conversely, the suppression of non-malignant tissues is one of the leading characteristics of the course of ALL. Both