Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Ondřej Hrušák"'
Autor:
Barbora Vakrmanová, Michaela Nováková, Petr Říha, Markéta Žaliová, Eva Froňková, Ester Mejstříková, Jan Starý, Ondřej Hrušák, Lucie Šrámková
Publikováno v:
Pediatric Blood & Cancer. 69
Daratumumab, an anti-CD38 antibody, is used experimentally in the treatment of relapsed acute lymphoblastic leukemia (ALL). We treated five patients suffering from relapsed ALL with daratumumab. Four patients had T ALL, three of whom achieved complet
Autor:
Jan Starý, Ondřej Hrušák
Publikováno v:
F1000Research, Vol 5 (2016)
Acute lymphoblastic leukemia (ALL) is the most common malignancy in childhood. Despite enormous improvement of prognosis during the last half century, ALL remains a major cause of childhood cancer-related mortality. During the past decade, whole geno
Externí odkaz:
https://doaj.org/article/1e3ddd56b5d44d9f97de1d99a6199df0
Autor:
Michaela Nováková, Markéta Žaliová, Martina Suková, Marcin Wlodarski, Aleš Janda, Eva Froňková, Vít Campr, Kateřina Lejhancová, Ondřej Zapletal, Dagmar Pospíšilová, Zdeňka Černá, Tomáš Kuhn, Peter Švec, Vendula Pelková, Zuzana Zemanová, Gitte Kerndrup, Marry van den Heuvel-Eibrink, Vincent van der Velden, Charlotte Niemeyer, Tomáš Kalina, Jan Trka, Jan Starý, Ondřej Hrušák, Ester Mejstříková
Publikováno v:
Haematologica, Vol 101, Iss 6 (2016)
GATA-2 deficiency was recently described as common cause of overlapping syndromes of immunodeficiency, lymphedema, familiar myelodysplastic syndrome or acute myeloid leukemia. The aim of our study was to analyze bone marrow and peripheral blood sampl
Externí odkaz:
https://doaj.org/article/b1018ecb74424ae1bb1e55581f1bd0c2
Autor:
Jan Starý, Ondřej Hrušák, Ondřej Pelák, Martina Vaskova, Tomas Kalina, Herbert Stadler, Daniel Thurner, Kristian Stanar, Marie-Luise Kiene, Jan Stuchlý, Daniela Kužílková
Publikováno v:
Cytometry Part A. 91:62-72
In mass cytometry, the isolation of pure lymphocytes is very important to obtain reproducible results and to shorten the time spent on data acquisition. To prepare highly purified cell suspensions of peripheral blood lymphocytes for further analysis
Autor:
Renata Formankova, Jan Starý, Ondřej Pelák, Ondřej Hrušák, Petr Hubacek, Petra Keslova, Jan Stuchlý, Petr Sedlacek, Tomas Kalina, L. Krol
Publikováno v:
Cytometry Part B: Clinical Cytometry. 92:380-388
Background Cytomegalovirus (CMV) specific T-cells are known to provide long-term control of CMV reactivation, which is a frequent complication of hematopoietic stem cell transplantation. We have studied 58 pediatric patients after hematopoietic stem
Autor:
Jan Stuchlý, Veronika Kanderová, Marcela Vlková, Ivana Heřmanová, Lucie Slámová, Ondřej Pelák, Eli Taraldsrud, Dalibor Jílek, Pavlína Králíčková, Børre Fevang, Marie Trková, Ondřej Hrušák, Eva Froňková, Anna Šedivá, Jiří Litzman, Tomáš Kalina
Publikováno v:
Scientific Reports
Common variable immunodeficiency (CVID) is a heterogeneous group of diseases. Our aim was to define sub-groups of CVID patients with similar phenotypes and clinical characteristics. Using eight-color flow cytometry, we analyzed both B- and T-cell phe
Autor:
Ester Mejstříková, Martina Vaskova, Vendula Pelkova, Jan Starý, Tomas Kalina, Denisa Petráčková, Jaroslav Weiser, Ondřej Hrušák, Markéta Žaliová, Martin Kovac
Publikováno v:
European Cytokine Network. 25:8-13
Acute lymphoblastic leukemia (ALL) cells depend on the microenvironment of the host in vivo and do not survive in in vitro culture. Conversely, the suppression of non-malignant tissues is one of the leading characteristics of the course of ALL. Both
Autor:
Ondřej Hrušák, Jean-Pierre Bourquin, Tomas Kalina, Barbara Buldini, Ester Mejstříková, Giuseppe Gaipa, Richard Ratei, Michael Dworzak, Giuseppe Basso, Drorit Luria, Eti Rozenthal, Mary Sartor, Leonid Karawajew
Publikováno v:
Cytometry Part B: Clinical Cytometry. 86:288-291
Background Flow cytometry is a valuable part in the routine diagnostics of acute leukemia (AL). Although internationally recognized definitions of main AL subsets are available, there is currently no consensus format for the short summary of clinical
Autor:
Jana Volejnikova, Elena Vodickova, Jan Stary, Zuzana Zemanova, Jean-Pierre Bourquin, Karel Fiser, Kamila Polgárová, Julia Starkova, Tomas Kalina, Jan Trka, Maria E. Figueroa, Ondřej Hrušák, G Cario, Lucie Slamova, Jan Zuna, Ester Mejstrikova, F van Delft, Leona Reznickova, Eva Fronkova, Beat Bornhauser, Marketa Zaliova, Michael Dworzak
Publikováno v:
Leukemia
Switches from the lymphoid to myeloid lineage during B-cell precursor acute lymphoblastic leukemia (BCP-ALL) treatment are considered rare and thus far have been detected in MLL-rearranged leukemia. Here, we describe a novel BCP-ALL subset, switching
Autor:
Jan Stuchlý, Veronika Kanderová, Marcela Vlková, Ivana Heřmanová, Lucie Slámová, Ondřej Pelák, Eli Taraldsrud, Dalibor Jílek, Pavlína Králíčková, Børre Fevang, Marie Trková, Ondřej Hrušák, Eva Froňková, Anna Šedivá, Jiří Litzman, Tomáš Kalina
Publikováno v:
Scientific Reports
Common variable immunodeficiency (CVID) is a heterogeneous group of diseases. Our aim was to define sub-groups of CVID patients with similar phenotypes and clinical characteristics. Using eight-color flow cytometry, we analyzed both B- and T-cell phe