Novel Insights into the Effect of Pythium Strains on Rapeseed Metabolism

Autor: Kateřina Bělonožníková, Kateřina Vaverová, Tomáš Vaněk, Miroslav Kolařík, Veronika Hýsková, Radomíra Vaňková, Petre Dobrev, Tomáš Křížek, Ondřej Hodek, Kateřina Čokrtová, Adam Štípek, Helena Ryšlavá

Publikováno v: Microorganisms, Vol 8, Iss 10, p 1472 (2020)

Pythium oligandrum is a unique biological control agent. This soil oomycete not only acts as a mycoparasite, but also interacts with plant roots and stimulates plant defense response via specific elicitors. In addition, P. oligandrum can synthetize a

Externí odkaz: https://doaj.org/article/840f16e96b9e413aa1b233f5dea57b6d

Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells

Autor: Alanna C. Green, Petra Marttila, Nicole Kiweler, Christina Chalkiadaki, Elisée Wiita, Victoria Cookson, Antoine Lesur, Kim Eiden, François Bernardin, Karl S. A. Vallin, Sanjay Borhade, Maeve Long, Elahe Kamali Ghahe, Julio J. Jiménez-Alonso, Ann-Sofie Jemth, Olga Loseva, Oliver Mortusewicz, Marianne Meyers, Elodie Viry, Annika I. Johansson, Ondřej Hodek, Evert Homan, Nadilly Bonagas, Louise Ramos, Lars Sandberg, Morten Frödin, Etienne Moussay, Ana Slipicevic, Elisabeth Letellier, Jérôme Paggetti, Claus Storgaard Sørensen, Thomas Helleday, Martin Henriksson, Johannes Meiser

Cancer cells fuel their increased need for nucleotide supply by upregulating one-carbon (1C) metabolism, including the enzymes methylenetetrahydrofolate dehydrogenase-cyclohydrolase 1 and 2 (MTHFD1 and MTHFD2). TH9619 is a potent inhibitor of dehydro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef4c9b031ee478e94f3df8742d2401f
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-206656

Structural elucidation of 3-nitrophenylhydrazine derivatives of tricarboxylic acid cycle acids and optimization of their fragmentation to boost sensitivity in liquid chromatography-mass spectrometry

Autor: Ondřej Hodek, John Henderson, Lidia Argemi-Muntadas, Adnan Khan, Thomas Moritz

Publikováno v: Hodek, O, Henderson, J, Argemi-Muntadas, L, Khan, A & Moritz, T 2023, ' Structural elucidation of 3-nitrophenylhydrazine derivatives of tricarboxylic acid cycle acids and optimization of their fragmentation to boost sensitivity in liquid chromatography-mass spectrometry ', Journal of Chromatography-B, vol. 1222, 123719 . https://doi.org/10.1016/j.jchromb.2023.123719

Carboxylic acids participate in many metabolic pathways including tricarboxylic acid (TCA) cycle. Therefore,there have been ongoing attempts to develop sensitive liquid chromatography-mass spectrometry methods overthe last decades. Derivatization of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc3cf37a3899d69bad5990fb9dd5cbd0
https://doi.org/10.1016/j.jchromb.2023.123719

Lidocaine adsorption to ethylene-vinyl acetate infusion bags decreases its availability in del Nido cardioplegia solution

Autor: Karel Nesměrák, Tomáš Křížek, Petr Kozlík, Eva Štěpánová, Ondřej Hodek

Publikováno v: Monatshefte für Chemie - Chemical Monthly. 151:1217-1223

Del Nido cardioplegia solution (dNCS) is frequently used in cardiac surgery. As dNCS is often in-house prepared by hospital pharmacies, an appropriate preparation and storage conditions need to be found and validated. In this study, an 8-week (i.e.,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ac0d4da836227aa39a269e74e074e07
https://doi.org/10.1007/s00706-020-02602-9

Impact of packaging properties on the physical-chemical-microbiological-sensory characteristics of Ricotta cheese during storage

Autor: Anca Mihaly Cozmuta, Gianni Sagratini, Manuela Cano‐Galey, Antonio Peñas, Robert Apjok, Ondřej Hodek, Franks Kamgang Nzekoue, Antonio Jesús Calahorro, Stefania Silvi, Anca Peter, Goran Drazic, Xiaohui Huang, Camelia Nicula, Leonard Mihaly Cozmuta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58698b3c542eb45c87c71f9eb67bbbd7
http://hdl.handle.net/11581/429375