Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Ondřej, Šeda"'
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 627 (2024)
Menopause brings about profound physiological changes, including the acceleration of insulin resistance and other abnormalities, in which adipose tissue can play a significant role. This study analyzed the effect of ovariectomy and estradiol substitu
Externí odkaz:
https://doaj.org/article/768b7a49f78c4bcabab8cecc7d5212be
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Quercetin, a flavonoid present in many fruits and vegetables, exhibits beneficial effects toward abnormalities related to metabolic syndrome. In this study, to further investigate metabolic and transcriptomic responses to quercetin supplementation, w
Externí odkaz:
https://doaj.org/article/9bbff0ece51243268b12e37dcc69f3eb
Autor:
Aleš Žák, Marie Jáchymová, Michal Burda, Barbora Staňková, Miroslav Zeman, Adolf Slabý, Marek Vecka, Ondřej Šeda
Publikováno v:
Metabolites, Vol 12, Iss 6, p 568 (2022)
Long-chain polyunsaturated fatty acids (LC-PUFAs) play important roles in human health, from controlling inflammation to lipid and glucose homeostasis. In our previous study, which employed a cluster analysis of a plasma fatty acid (FA) pattern, we i
Externí odkaz:
https://doaj.org/article/551dec8948fd48018e5e5f692ff2e108
Autor:
Elena Školníková, Lucie Šedová, Blanka Chylíková, Adéla Kábelová, František Liška, Ondřej Šeda
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Overnutrition in pregnancy and lactation affects fetal and early postnatal development, which can result in metabolic disorders in adulthood. We tested a hypothesis that variation of the Zbtb16 gene, a significant energy metabolism regulator, modulat
Externí odkaz:
https://doaj.org/article/caf731c25a99432e8d892b53851c2f52
Single-Gene Congenic Strain Reveals the Effect of Zbtb16 on Dexamethasone-Induced Insulin Resistance
Autor:
Michaela Krupková, František Liška, Ludmila Kazdová, Lucie Šedová, Adéla Kábelová, Drahomíra Křenová, Vladimír Křen, Ondřej Šeda
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
BackgroundGlucocorticoids (GCs) are potent therapeutic agents frequently used for treatment of number of conditions, including hematologic, inflammatory, and allergic diseases. Both their therapeutic and adverse effects display significant interindiv
Externí odkaz:
https://doaj.org/article/9c7cdc0d50c44b5db42f54f46828053e
Autor:
Ondřej Šeda, Kristýna Junková, Hana Malinska, Adéla Kábelová, Martina Hüttl, Michaela Krupková, Irena Markova, František Liška, Lucie Šedová
Publikováno v:
Nutrients; Volume 14; Issue 16; Pages: 3428
Several corresponding regions of human and mammalian genomes have been shown to affect sensitivity to the manifestation of metabolic syndrome via nutrigenetic interactions. In this study, we assessed the effect of sucrose administration in a newly es
Autor:
Lucie Šedová, Michal Pravenec, Drahomíra Křenová, Ludmila Kazdová, Václav Zídek, Michaela Krupková, František Liška, Vladimír Křen, Ondřej Šeda
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152708 (2016)
Metabolic syndrome is a highly prevalent human disease with substantial genomic and environmental components. Previous studies indicate the presence of significant genetic determinants of several features of metabolic syndrome on rat chromosome 16 (R
Externí odkaz:
https://doaj.org/article/0157da71515941e68e4923ba903ef77c
Autor:
Aleš Hořínek, Ondřej Šeda, Eva Pazourkova, Iveta Zednikova, Miroslava Krkavcová, Blanka Chylíková, Pavel Calda, Marie Korabecna, Miroslav Břešťák
Publikováno v:
Molecular Biology Reports
Down syndrome (DS) is one of the most common causes of intellectual disability and new approaches allowing its rapid and effective prenatal detection are being explored. In this study, we investigated the diagnostic potential of plasma microRNAs (miR
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134424 (2015)
Externí odkaz:
https://doaj.org/article/54c0ee9c4132426a940d36621adf093b
Autor:
Lucie Šedová, Jan Prochazka, Dagmar Zudová, Běla Bendlová, Josef Včelák, Radislav Sedlacek, Ondřej Šeda
Publikováno v:
Genes
Volume 12
Issue 7
Genes, Vol 12, Iss 1087, p 1087 (2021)
Volume 12
Issue 7
Genes, Vol 12, Iss 1087, p 1087 (2021)
Complex metabolic conditions such as type 2 diabetes and obesity result from the interaction of numerous genetic and environmental factors. While the family of Nme proteins has been connected so far mostly to development, proliferation, or ciliary fu