Zobrazeno 1 - 10
of 350
pro vyhledávání: '"Onconase"'
Autor:
Gotte, Giovanni a, ⁎, 1, Campagnari, Rachele a, 1, Loreto, Domenico b, Bettin, Ilaria a, Calzetti, Federica c, Menegazzi, Marta a, ⁎, Merlino, Antonello b, ⁎
Publikováno v:
In International Journal of Biological Macromolecules 30 November 2021 191:560-571
Autor:
Yesuf Adem Siraj
Publikováno v:
Translational Medicine Communications, Vol 7, Iss 1, Pp 1-17 (2022)
Abstract Background Following an increasing interest in exploration of anticancer chemotherapeutic agents, ribonucleases are currently under investigations for alternative anticancer chemotherapy. Objective The current review scrutinizes information
Externí odkaz:
https://doaj.org/article/d9a2b5c4049746ce96d43a8de6577b95
Publikováno v:
In Biochemical Pharmacology September 2019 167:173-181
Publikováno v:
Cancer Cell International, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Immunotoxins are typical therapeutic drugs that can target cancer cells. They exploit the affinity of specific monoclonal antibodies or ligands to cancer cells to deliver a conjugated protein toxin to target sites, thus, attacking
Externí odkaz:
https://doaj.org/article/2239b5ed61d24adcbc2070349c9de389
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1998 Sep 01. 95(18), 10407-10412.
Externí odkaz:
https://www.jstor.org/stable/45903
Publikováno v:
The Journal of Physical Chemistry B. 126:7934-7942
The unfolded state of proteins presents many challenges to elucidate the structural basis for biological function. This state is characterized by a large degree of structural heterogeneity which makes it difficult to generate structural models. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9d22d61dcb5082980d5e548544a984
https://doi.org/10.1021/acs.jpcb.2c04770
https://doi.org/10.1021/acs.jpcb.2c04770
Autor:
Antonello Merlino, Giovanni Gotte, Rachele Campagnari, Domenico Loreto, Federica Calzetti, Ilaria Bettin, Marta Menegazzi
Publikováno v:
International Journal of Biological Macromolecules. 191:560-571
Onconase (ONC) is a monomeric amphibian "pancreatic-type" RNase endowed with remarkable anticancer activity. ONC spontaneously forms traces of a dimer (ONC-D) in solution, while larger amounts can be formed when ONC is lyophilized from mildly acidic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81b626f9f74eb3c1ea0c88d19a6aefb
https://doi.org/10.1016/j.ijbiomac.2021.09.095
https://doi.org/10.1016/j.ijbiomac.2021.09.095
Autor:
Fiorini, Claudia a, Cordani, Marco a, Gotte, Giovanni a, Picone, Delia b, Donadelli, Massimo a, ⁎
Publikováno v:
In BBA - Molecular Cell Research March 2015 1853(3):549-560
Autor:
Kiesgen, Stefan a, Arndt, Michaela A.E. a, b, Körber, Christoph c, Arnold, Ulrich d, Weber, Tobias a, Halama, Niels a, Keller, Armin a, Bötticher, Benedikt a, Schlegelmilch, Anne a, Liebers, Nora a, Cremer, Martin a, Herold-Mende, Christel e, f, Dyckhoff, Gerhard f, Federspil, Philippe A. g, Jensen, Alexandra D. h, i, Jäger, Dirk a, Kontermann, Roland E. j, Mier, Walter k, Krauss, Jürgen a, *
Publikováno v:
In Cancer Letters 1 February 2015 357(1):364-373