Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Oncolytic herpes simplex virus"'
Autor:
Jing Wang, Lei Tian, Tasha Barr, Lewei Jin, Yuqing Chen, Zhiyao Li, Ge Wang, Jian-Chang Liu, Li-Shu Wang, Jianying Zhang, David Hsu, Mingye Feng, Michael A. Caligiuri, Jianhua Yu
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 3, Pp 200824- (2024)
Limited therapeutic options are available for patients with breast cancer brain metastases (BCBM), and thus there is an urgent need for novel treatment approaches. We previously engineered an effective oncolytic herpes simplex virus 1 (oHSV) expressi
Externí odkaz:
https://doaj.org/article/b03901e2c0404d4bafa98fbbe8c6c84b
Autor:
Lei Wang, Xusha Zhou, Xiaoqing Chen, Yuanyuan Liu, Yue Huang, Yuan Cheng, Peigen Ren, Jing Zhao, Grace Guoying Zhou
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 2, Pp 200799- (2024)
Glioblastoma is the most common and aggressive malignant brain tumor and has limited treatment options. Hence, innovative approaches are urgently needed. Oncolytic virus therapy is emerging as a promising modality for cancer treatment due to its tumo
Externí odkaz:
https://doaj.org/article/cd4ea2c7d88b48ed9a3cac689ad4b62d
Autor:
Andrea Vannini, Federico Parenti, Cristina Forghieri, Catia Barboni, Anna Zaghini, Gabriella Campadelli-Fiume, Tatiana Gianni
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/7a56846e59814393a6d271683d73d840
Autor:
Yeaseul Kim, Uksha Saini, Doyeon Kim, Ilse Hernandez-Aguirre, Jack Hedberg, Alexia Martin, Xiaokui Mo, Timothy P. Cripe, James Markert, Kevin A. Cassady, Ravi Dhital
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionMalignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas with unacceptably low cure rates occurring often in patients with neurofibromatosis 1 defects. To investigate oncolytic Herpes Simplex Virus (oHSV) as an immunother
Externí odkaz:
https://doaj.org/article/5f74ff6d85764633914ea8330bf8e162
Autor:
Hyun-Yoo Joo, Hyunjung Baek, Chun-Seob Ahn, Eun-Ran Park, Youngju Lee, Sujung Lee, Mihee Han, Bora Kim, Yong-Hoon Jang, Heechung Kwon
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 1, Pp 200778- (2024)
To retarget oncolytic herpes simplex virus (oHSV) to cancer-specific antigens, we designed a novel, double-retargeted oHSV platform that uses single-chain antibodies (scFvs) incorporated into both glycoprotein H and a bispecific adapter expressed fro
Externí odkaz:
https://doaj.org/article/41a1e3c9070c4974806af9d7cf604660
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/144f671383554818b2132632bc890ec3
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Recurrent glioma treatment is challenging due to molecular heterogeneity and treatment resistance commonly observed in these tumors. Researchers are actively pursuing new therapeutic strategies. Oncolytic viruses have emerged as a promising option. O
Externí odkaz:
https://doaj.org/article/313f064c1cc741e5afaa29d5bebef84e
Akademický článek
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Akademický článek
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Autor:
Defeng Kong, Zhenrong Yang, Guoliang Li, Quanyou Wu, Zhaoru Gu, Duo Wan, Qi Zhang, Xiaoli Zhang, Shujun Cheng, Binlei Liu, Kaitai Zhang, Wen Zhang
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background The combination of oncolytic viruses (OVs) with immune checkpoint blockades is a research hotspot and has shown good efficacy. Here, we present the first attempt to combine oncolytic herpes simplex virus 2 (OH2) with an anti-SIRP
Externí odkaz:
https://doaj.org/article/45d1220f7b74487f9c17dc77eb752da0