Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Oncology/Genitourinary Cancers"'
Autor:
Janine Senz, Malachi Griffith, Sohrab P. Shah, Alireza Heravi Moussavi, David G. Huntsman, Torsten O. Nielsen, Marina Pacheco, Gavin Ha, Martin Hirst, Marco A. Marra, Nataliya Melnyk, Mark G. F. Sun, S. Cenk Sahinalp, Ryan Giuliany, Fereydoun Hormozdiari, Abdalnasser Zayed, Andrew McPherson
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 5, p e1001138 (2011)
PLoS Computational Biology
PLoS Computational Biology
Gene fusions created by somatic genomic rearrangements are known to play an important role in the onset and development of some cancers, such as lymphomas and sarcomas. RNA-Seq (whole transcriptome shotgun sequencing) is proving to be a useful tool f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54bfa6c8a8abd670bc8ddc4900713674
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21625565/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21625565/?tool=EBI
Autor:
John K. Wiencke, Angeline S. Andrew, Heather H. Nelson, Brock C. Christensen, Margaret R. Karagas, E. Andres Houseman, Margaret Wrensch, Luc Gagne, Karl T. Kelsey, Alan R. Schned, Carmen J. Marsit, Shichun Zheng, Joseph L. Wiemels
Publikováno v:
PloS one, vol 5, iss 8
PLoS ONE
PLoS ONE, Vol 5, Iss 8, p e12334 (2010)
PLoS ONE
PLoS ONE, Vol 5, Iss 8, p e12334 (2010)
Approximately 500,000 individuals diagnosed with bladder cancer in the U.S. require routine cystoscopic follow-up to monitor for disease recurrences or progression, resulting in over $2 billion in annual expenditures. Identification of new diagnostic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5686720952a670aa99769273100521
https://escholarship.org/uc/item/3gs6g0kf
https://escholarship.org/uc/item/3gs6g0kf
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10857 (2010)
PLoS ONE
PLoS ONE
Background Carbonic anhydrase IX (CAIX) is a membrane spanning protein involved in the enzymatic regulation of tumor acid-base balance. CAIX has been shown to be elevated in a number of hypoxic tumor types. The purpose of this study was to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2b07298112e94760f2d124b15a70ab
http://europepmc.org/articles/PMC2877709?pdf=render
http://europepmc.org/articles/PMC2877709?pdf=render
Autor:
Kim Anh Do, William A. Murphy, Wei Qiao, Evan M. Johnson, Vikas Kundra, Dianna D. Cody, Charles R. Sikes, Nora M. Navone, Chaan Ng, Murali Ravoori, Aneta J. Czaplinska, Lin Han
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9854 (2010)
PLoS ONE
PLoS ONE
BACKGROUND To compare nondestructive in vivo and ex vivo micro-computed tomography (muCT) and ex vivo dual-energy-X-ray-absorptiometry (DXA) in characterizing mineralized cortical and trabecular bone response to prostate cancer involving the skeleton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4239d44fa42ea3a2ebb8faacde9ff6da
http://europepmc.org/articles/PMC2847943?pdf=render
http://europepmc.org/articles/PMC2847943?pdf=render
Autor:
Charles J. Bieberich, Chi V. Dang, Angelo M. De Marzo, Matthew T. Lotz, Tamara L. Lotan, William G. Nelson, Jessica L. Hicks, Denise Schultz, Uzoma A. Anele, Cheryl M. Koh, Laura N. Mutton, Gretchen K. Hubbard, Carlise R. Bethel, Tsuyoshi Iwata, Srinivasan Yegnasubramanian, Meng Meng Xu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 2, p e9427 (2010)
PLoS ONE, Vol 5, Iss 2, p e9427 (2010)
Lo-MYC and Hi-MYC mice develop prostatic intraepithelial neoplasia (PIN) and prostatic adenocarcinoma as a result of MYC overexpression in the mouse prostate[1]. However, prior studies have not determined precisely when, and in which cell types, MYC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9addcfec018982d358ef22b035b50bb7
https://pubmed.ncbi.nlm.nih.gov/20195545
https://pubmed.ncbi.nlm.nih.gov/20195545
Autor:
Chana Palmer, Patrick O. Brown
Publikováno v:
PLoS Medicine, Vol 6, Iss 7, p e1000114 (2009)
PLoS Medicine
PLoS Medicine
Pat Brown and colleagues carry out a modeling study and define what properties a biomarker-based screening test would require in order to be clinically useful.
Background Ovarian cancer kills approximately 15,000 women in the United States every
Background Ovarian cancer kills approximately 15,000 women in the United States every
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4efd8747d00ccf5ce654ae3fed718fe6
http://europepmc.org/articles/PMC2711307?pdf=render
http://europepmc.org/articles/PMC2711307?pdf=render
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13266 (2010)
PLoS ONE
PLoS ONE
We conducted studies in Vanuatu to evaluate potential screening and treatment strategies to assist with control of cervical cancer. In a pilot study of 496 women, visual inspection and cytology were evaluated as screening tests for detection of CIN 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a02e4d9e7e6bf94b0650297a0b77cf
https://doi.org/10.1371/journal.pone.0013266
https://doi.org/10.1371/journal.pone.0013266
Autor:
Madeleine S.Q. Kortenhorst, Luigi Marchionni, Nadine Rosmus, Theodore L. DeWeese, Spencer J. Collis, Justin Deangelis, Hans J. Hammers, Michael A. Carducci, Janet Mendonca, Johan W.R. Nortier, Mohammad Hedayati, Sushant Kachhap, Michel D. Wissing, Shabana Shabbeer, Jianqing Lin, Naseruddin Höti
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 6, p e11208 (2010)
PLoS ONE, Vol 5, Iss 6, p e11208 (2010)
Background Histone deacetylase inhibitors (HDACis) re-express silenced tumor suppressor genes and are currently undergoing clinical trials. Although HDACis have been known to induce gene expression, an equal number of genes are downregulated upon HDA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfca2c2e66287bd8ef3ddc5a133d79e
https://doi.org/10.1371/journal.pone.0011208
https://doi.org/10.1371/journal.pone.0011208
Autor:
Angelita G. Utleg, Gilbert S. Omenn, Daehee Hwang, Xiaowei Yan, Xuefeng Fang, Ji-Hoon Cho, Biaoyang Lin, Dustin E. Schones, Danielle Yi, Leroy Hood, Keji Zhao, Xu Hong, Jun Wang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 8, p e6589 (2009)
PLoS ONE, Vol 4, Iss 8, p e6589 (2009)
Background The androgen receptor (AR) plays important roles in the development of male phenotype and in different human diseases including prostate cancers. The AR can act either as a promoter or a tumor suppressor depending on cell types. The AR pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5dc0b8df6fa24f43508b53506305deb
https://doi.org/10.1371/journal.pone.0006589
https://doi.org/10.1371/journal.pone.0006589
Autor:
Si Brask Sonne, Henrik Leffers, John E. Nielsen, Marlene Danner Dalgaard, Christina E. Hoei-Hansen, Ewa Rajpert-De Meyts, Lise Mette Rahbek Gjerdrum
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5536 (2009)
Sonne, S B, Dalgaard, M D, Nielsen, J E, Hoei-Hansen, C E, Rajpert-De Meyts, E, Gjerdrum, L M & Leffers, H 2009, ' Optimizing Staining Protocols for Laser Microdissection of Specific Cell Types from the Testis Including Carcinoma In Situ ', PLoS ONE, vol. 4, no. 5, pp. e5536 . https://doi.org/10.1371/journal.pone.0005536
PLoS ONE
Sonne, S B, Dalgaard, M D, Nielsen, J E, Hoei-Hansen, C E, Rajpert-De Meyts, E, Gjerdrum, L M & Leffers, H 2009, ' Optimizing Staining Protocols for Laser Microdissection of Specific Cell Types from the Testis Including Carcinoma In Situ ', PLoS ONE, vol. 4, no. 5, pp. e5536 . https://doi.org/10.1371/journal.pone.0005536
PLoS ONE
Udgivelsesdato: May 2009 Microarray and RT-PCR based methods are important tools for analysis of gene expression; however, in tissues containing many different cells types, such as the testis, characterization of gene expression in specific cell type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777aa64e49df3a5981670026ff0af556
https://doi.org/10.1371/journal.pone.0005536
https://doi.org/10.1371/journal.pone.0005536