Zobrazeno 1 - 10
of 437
pro vyhledávání: '"Oncogenomics"'
Autor:
Gabriel Arantes dos Santos, Kasit Chatsirisupachai, Roberto A. Avelar, João Pedro de Magalhães
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Introduction Understanding changes in cell identity in cancer and ageing is of great importance. In this work, we analyzed how gene expression changes in human tissues are associated with tissue specificity during cancer and ageing using tra
Externí odkaz:
https://doaj.org/article/3bf8913d93d947f090dcb06299fb0d6e
Autor:
Rosie O’Shea, Ashley Crook, Chris Jacobs, Maira Kentwell, Margaret Gleeson, Katherine M. Tucker, Heather Hampel, Alanna Kulchak Rahm, Natalie Taylor, Sarah Lewis, Nicole M. Rankin
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Introduction“Mainstreaming” is a proposed strategy to integrate genomic testing into oncology. The aim of this paper is to develop a mainstreaming oncogenomics model by identifying health system interventions and implementation strategies for mai
Externí odkaz:
https://doaj.org/article/42a7b5f256154dbda012c9e160b6e65c
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Triple-negative breast cancer (TNBC) is a rare variant of breast cancer (BC) known to be aggressive and refractory. TNBC lacks effective early diagnostic and therapeutic options leading to poorer outcomes. The genomic landscape and alterations leadin
Externí odkaz:
https://doaj.org/article/f1bf314b5a1e4404b6d670e7c4365516
Autor:
Giulia Maria Stella, Sara Lettieri, Davide Piloni, Ilaria Ferrarotti, Fabio Perrotta, Angelo Guido Corsico, Chandra Bortolotto
Publikováno v:
Pharmaceuticals, Vol 16, Iss 7, p 1042 (2023)
Background and rationale. The therapeutic interventions against lung cancer are currently based on a fully personalized approach to the disease with considerable improvement of patients’ outcome. Alongside continuous scientific progresses and resea
Externí odkaz:
https://doaj.org/article/cd95c8f0e0f844bfad37e751be292981
Autor:
N. Ari Wijetunga, Carlos H. dos Anjos, W. Iris Zhi, Mark Robson, C. Jillian Tsai, Yoshiya Yamada, Laura Dover, Erin F. Gillespie, Amy J. Xu, Jonathan T. Yang
Publikováno v:
Cancer Medicine, Vol 10, Iss 15, Pp 5163-5174 (2021)
Abstract Purpose We examined the characteristics of breast cancer patients with oligometastases (OM) treated with stereotactic ablative body radiotherapy (SABR) to identify factors associated with local progression, distant metastasis progression, ti
Externí odkaz:
https://doaj.org/article/cd43f585124e4b7c9181d4a756d81078
Akademický článek
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Autor:
Heidelinde Sammallahti, Virinder Kaur Sarhadi, Arto Kokkola, Reza Ghanbari, Sama Rezasoltani, Hamid Asadzadeh Aghdaei, Pauli Puolakkainen, Sakari Knuutila
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 652 (2022)
Pancreatic cancer (PC) is an aggressive malignancy with a dismal prognosis. To improve patient survival, the development of screening methods for early diagnosis is pivotal. Oncogenomic alterations present in tumor tissue are a suitable target for no
Externí odkaz:
https://doaj.org/article/5899769943704ca0ab84dc4a5396ca37
Akademický článek
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Autor:
Marco Chierici, Nicole Bussola, Alessia Marcolini, Margherita Francescatto, Alessandro Zandonà, Lucia Trastulla, Claudio Agostinelli, Giuseppe Jurman, Cesare Furlanello
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Recent technological advances and international efforts, such as The Cancer Genome Atlas (TCGA), have made available several pan-cancer datasets encompassing multiple omics layers with detailed clinical information in large collection of samples. The
Externí odkaz:
https://doaj.org/article/b72d458651dc48dfac3b3f6a5129cd79
Autor:
Heidelinde Sammallahti, Arto Kokkola, Sama Rezasoltani, Reza Ghanbari, Hamid Asadzadeh Aghdaei, Sakari Knuutila, Pauli Puolakkainen, Virinder Kaur Sarhadi
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12978 (2021)
Pancreatic cancer (PC) is an aggressive disease with a high mortality and poor prognosis. The human microbiome is a key factor in many malignancies, having the ability to alter host metabolism and immune responses and participate in tumorigenesis. Gu
Externí odkaz:
https://doaj.org/article/7d00e8275b534c0688fb993150aa4147