Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes

Autor: Carole Ober, Torben Hansen, Colin N. A. Palmer, Adalheidur Olafsdottir, Steinunn Thorlacius, Unnur Thorsteinsdottir, Muredach P. Reilly, Adam Baker, Eirikur Jonsson, Dorine W. Swinkels, Agnar Helgason, Thorarinn Blondal, Rafn Benediktsson, Erica Van Boven, Brian K. Suarez, Gudmundur V. Einarsson, M. Ruiz-Echarri, Lambertus A. Kiemeney, Dana Magnusdottir, Claus Christiansen, Charles N. Rotimi, Torben Jørgensen, John Cashy, Gitte Andersen, Birgitta Birgisdottir, Robert L. Wilensky, Margret Jakobsdottir, Maggie C.Y. Ng, Kari Stefansson, Kristleifur Kristjansson, Jie Zhou, Asgeir Sigurdsson, Kari T. Kristinsson, Jeffrey R. Gulcher, Andrei Manolescu, Yu Z. Bagger, Thorunn Rafnar, Julius Gudmundsson, Daniel J. Rader, Wing-Yee So, Steinunn Gunnarsdottir, Alejandro Tres, Gunnar Sigurdsson, Marten H. Hofker, Juliana C.N. Chan, Fernando Fuertes, Berta Saez, Charlotte H. Kimber, Siem M. Klaver, Andrew D. Morris, Laura Asín, Daniel F. Gudbjartsson, Gerdur Stefansdottir, William J. Catalona, Bjarni A. Agnarsson, Rosa B. Barkardottir, Kristrun R. Benediktsdottir, Onco Van Vierssen Trip, Jon Thor Bergthorsson, Adebowale Adeyemo, Shyamali Ghosh, Jose I. Mayordomo, Patrick Sulem, Michael L. Frigge, Valgerdur Steinthorsdottir, Theresa Graif, Augustine Kong, Katja K.H. Aben, Peter C.Y. Tong, Simon N. Stacey, Oluf Pedersen, Knut Borch-Johnsen, Yuanxiu Chen, Cisca Wijmenga, Gudmar Thorleifsson

Publikováno v: Nature Genetics, 39, 8, pp. 977-83
Nature Genetics, 39(8), 977-983. Nature Publishing Group
Nature Genetics, 39, 977-83

We performed a genome-wide association scan to search for sequence variants conferring risk of prostate cancer using 1,501 Icelandic men with prostate cancer and 11,290 controls. Follow-up studies involving three additional case-control groups replic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ccab1f92577c5798b028d0e2ddb5b4a
https://hdl.handle.net/2066/52115