Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Omri Wolk"'
Autor:
Nataliia Stepanenko, Omri Wolk, Enrica Bianchi, Gavin James Wright, Natali Schachter-Safrai, Kiril Makedonski, Alberto Ouro, Assaf Ben-Meir, Yosef Buganim, Amiram Goldblum
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Combined hormone drugs are the basis for orally administered contraception. However, they are associated with severe side effects that are even more impactful for women in developing countries, where resources are limited. The risk of side effects ma
Externí odkaz:
https://doaj.org/article/f2cb5811de864636b916150553867994
Autor:
Omri Wolk, Amiram Goldblum
Publikováno v:
Journal of chemical information and modeling.
Targeting protein-protein interactions (PPIs) by small molecule modulators (iPPIs) is an attractive strategy for drug therapy, and some iPPIs have already been introduced into the clinic. Blocking PPIs is however considered to be a more difficult tas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7656d500f6785183b3c1b88738f39a
https://pubmed.ncbi.nlm.nih.gov/36512704
https://pubmed.ncbi.nlm.nih.gov/36512704
Autor:
Olga Kister, Carmil Azran, Arik Dahan, Moran Zur, Peter Langguth, Omri Wolk, David Czeiger, Noa Fine-Shamir, Gad Shaked, Gilbert Sebbag
Publikováno v:
Obesity Reviews. 17:1050-1066
Bariatric surgery is the most effective solution for severe obesity and obesity with comorbidities, and the number of patients going through bariatric surgery is rapidly and constantly growing. The modified gastrointestinal anatomy of the patient may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce9536c02ccc1ce00def2d086a4ee842
https://doi.org/10.1111/obr.12434
https://doi.org/10.1111/obr.12434
Autor:
Milica Markovic, Daniel Porat, Omri Wolk, Avital Beig, Arik Dahan, Moran Zur, Noa Fine-Shamir
Publikováno v:
Journal of pharmaceutical sciences. 108(1)
The goal of this work was to develop an in silico model that allows predicting segmental-dependent permeability throughout the small intestine (SI). In vivo permeability of 11 model drugs in 3 SI segments (jejunum, mid-SI, ileum) was studied in rats,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007e5423f0f8a0843212fa646024f072
https://pubmed.ncbi.nlm.nih.gov/30055228
https://pubmed.ncbi.nlm.nih.gov/30055228
Autor:
Arik Dahan, Jennifer B. Dressman, Omri Wolk, Vinod P. Shah, D.W. Groot, Bertil Abrahamsson, Peter Langguth, James E. Polli, Rodrigo Cristofoletti, Moran Zur, Sabine Kopp, Gordon L. Amidon
Publikováno v:
Journal of Pharmaceutical Sciences. 103:1592-1600
The present monograph reviews data relevant to applying the biowaiver procedure for the approval of immediate-release multisource solid dosage forms containing codeine phosphate. Both biopharmaceutical and clinical data of codeine were assessed. Solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f54b48821e8634cfa8da563b12f2696
https://doi.org/10.1002/jps.23977
https://doi.org/10.1002/jps.23977
Publikováno v:
Expert Opinion on Drug Delivery. 10:1275-1286
Inflammatory bowel disease (IBD) is an exceptional scenario with regard to drug targeting, as oral administration has the potential to deliver the drug directly to the site(s) of action. Consequently, retention of the drug within the intestinal lumen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bca48575041e40ce9f4769a45eb06787
https://doi.org/10.1517/17425247.2013.800480
https://doi.org/10.1517/17425247.2013.800480
Autor:
Carmil, Azran, Omri, Wolk, Moran, Zur, Noa, Fine-Shamir, Gad, Shaked, David, Czeiger, Gilbert, Sebbag, Olga, Kister, Peter, Langguth, Arik, Dahan
Publikováno v:
Obesity reviews : an official journal of the International Association for the Study of Obesity. 17(11)
Bariatric surgery is the most effective solution for severe obesity and obesity with comorbidities, and the number of patients going through bariatric surgery is rapidly and constantly growing. The modified gastrointestinal anatomy of the patient may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::122a9f77d19db0926dab5e8117389c9a
https://pubmed.ncbi.nlm.nih.gov/27335140
https://pubmed.ncbi.nlm.nih.gov/27335140
Autor:
Matilde Merino-Sanjuán, Omri Wolk, Isabel González-Álvarez, Avital Beig, Moran Zur, Marival Bermejo, Marta González-Álvarez, Arik Dahan, Isabel Lozoya-Agullo
Publikováno v:
International journal of pharmaceutics. 480(1-2)
Intestinal drug permeability has been recognized as a critical determinant of the fraction dose absorbed, with direct influence on bioavailability, bioequivalence and biowaiver. The purpose of this research was to compare intestinal permeability valu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c226eea02045637bc1aac044316acde
https://pubmed.ncbi.nlm.nih.gov/25595387
https://pubmed.ncbi.nlm.nih.gov/25595387
The low/high BCS permeability class boundary: physicochemical comparison of metoprolol and labetalol
Publikováno v:
Molecular pharmaceutics. 11(5)
Although recognized as overly conservative, metoprolol is currently the common low/high BCS permeability class boundary reference compound, while labetalol was suggested as a potential alternative. The purpose of this study was to identify the variou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a530eeffb46512ad3d2556251ab7851e
https://pubmed.ncbi.nlm.nih.gov/24735251
https://pubmed.ncbi.nlm.nih.gov/24735251
Autor:
Arik Dahan, Omri Wolk
Publikováno v:
Advances in Delivery Science and Technology ISBN: 9781461494331
The intestinal tract is a long and complex organ, with significantly variable characteristics throughout it. It is broadly divided to several segments: the small intestine, which is subdivided to duodenum, jejunum, and ileum, and the colon. Each segm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28a2efe91104d7cb82958b7a408d230b
https://doi.org/10.1007/978-1-4614-9434-8_16
https://doi.org/10.1007/978-1-4614-9434-8_16
