Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Omprakash Tanwar"'
Autor:
Omprakash Tanwar, Aastha Soni, Pawan Prajapat, Tanu Shivhare, Pooja Pandey, Puneet Kumar Samaiya, Sharad Prakash Pandey, Parimal Kar
Publikováno v:
ACS Omega, Vol 6, Iss 11, Pp 7754-7760 (2021)
Externí odkaz:
https://doaj.org/article/e20b0ccf436d4a84a5101eeaa30bc537
Autor:
Saloni Yadav, Aastha Soni, Omprakash Tanwar, Rajendra Bhadane, Gurdyal S. Besra, Neha Kawathekar
Publikováno v:
ChemMedChem.
Publikováno v:
Molecular diversity.
To fight against the devastating coronavirus disease 2019 (COVID-19), identifying robust anti-SARS-CoV-2 therapeutics from all possible directions is necessary. To contribute to this effort, we selected a human metabolites database containing waters
Autor:
Puneet Kumar Samaiya, Aastha Soni, Sharad Prakash Pandey, Tanu Shivhare, Omprakash Tanwar, Pooja Pandey, Pawan Prajapat, Parimal Kar
Publikováno v:
ACS Omega, Vol 6, Iss 11, Pp 7754-7760 (2021)
ACS Omega
ACS Omega
COVID-19 is a deadly pandemic and has resulted in a huge loss of money and life in the past few months. It is well known that the SARS-CoV-2 gene mutates relatively slowly as compared to other viruses but still may create hurdles in developing vaccin
Autor:
Kalicharan Sharma, Dharmarajan Sriram, Shakir Ali, Vagolu Siva Krishna, Omprakash Tanwar, M. S. Zaman, Mymoona Akhter, Girdhar Singh Deora, Mohammad Mumtaz Alam
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:1421-1429
A series of 1-(1-benzyl-2-methyl-5-((1-phenyl-1H-1,2,3-triazol-4-yl)methoxy)-1H-indol-3-yl)ethanone and ethyl 1-benzyl-2-methyl-5-((1-phenyl-1H-1,2,3-triazol-4-yl)methoxy)-1H-indole-3-carboxylate derivatives were designed based on bioisosteric replac
Autor:
Mymoona Akhter, Omprakash Tanwar, Kalicharan Sharma, M. S. Zaman, Shakir Ali, Shweta Sharma, Mohammad Mumtaz Alam
Publikováno v:
Bioorganic Chemistry. 80:319-333
Tuberculosis is an infectious disease that affects millions of population every year. Mtb-DHFR is a validated target that is vital for nucleic acids biosynthesis and therefore DNA formation and cell replication. This paper report identification and s
Autor:
Gautam Kumar, Mymoona Akhter, M S Zama, Mumtaz Alam, Omprakash Tanwar, Supriya Sharma, C R Pillai, Jitender Kumar
Publikováno v:
European Journal of Medicinal Chemistry. 149:139-147
A series of pyrazole-pyrazoline substituted with benzenesulfonamide were synthesized and evaluated for their antimalarial activity in vitro and in vivo. The compounds were active against both chloroquine (CQ) sensitive (3D7) and CQ resistant (RKL-9)
Autor:
Garima Verma, Akranth Marella, Mohammad Mumtaz Alam, Mymoona Akhter, Mohammad Shaquiquzzaman, Omprakash Tanwar
Publikováno v:
Medicinal Chemistry Research. 24:1018-1037
The paper herein describes the synthesis of pyrimidine nitrile-pyrazoline hybrid molecules as potential agents to treat malaria. The synthesized compounds were found active against the 3D7 strain of P. falciparum. Compounds 25, 26, 45 and 46 exhibite
Publikováno v:
Medicinal Chemistry Research. 24:879-890
3-[(2-Chloroquinolin-3-yl) methylene]-5-phenylfuran-2(3H)-one derivatives (6a–j and 7a–j) have been synthesized and evaluated for their antimalarial activity. Three compounds 7d, 7f, and 7g showed excellent activity (0.50–0.72 µg/mL). In addit
Autor:
Syed Ovais, Kalim Javed, H. Pushpalatha, Mymoona Akthar, Rafia Bashir, Pooja Rathore, Omprakash Tanwar, G. Bhanuprakash Reddy, Alhamza Dheyaa, Shafiya Yaseen, Mohammed Samim, Raed Yaseen
Publikováno v:
European Journal of Medicinal Chemistry. 80:209-217
Seventeen new pyrazoline substituted benzenesulfonylurea/thiourea derivatives (2a–q) were synthesized and characterized by elemental analysis and various spectroscopic techniques viz; IR, 1H NMR, 13C NMR, and MS data. Thirteen compounds showed mode