Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Omolola Eniola‐Adefeso"'
Autor:
Alison L. Banka, M. Valentina Guevara, Emma R. Brannon, Nhien Q. Nguyen, Shuang Song, Gillian Cady, David J. Pinsky, Kathryn E. Uhrich, Reheman Adili, Michael Holinstat, Omolola Eniola-Adefeso
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract The combination of inflammation and thrombosis is a hallmark of many cardiovascular diseases. Under such conditions, platelets are recruited to an area of inflammation by forming platelet-leukocyte aggregates via interaction of PSGL-1 on leu
Externí odkaz:
https://doaj.org/article/caeda1dbe64e41b38302bf6fa0635e66
Autor:
Yun Chang, Xuechao Cai, Ramizah Syahirah, Yuxing Yao, Yang Xu, Gyuhyung Jin, Vijesh J. Bhute, Sandra Torregrosa-Allen, Bennett D. Elzey, You-Yeon Won, Qing Deng, Xiaojun Lance Lian, Xiaoguang Wang, Omolola Eniola-Adefeso, Xiaoping Bao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Glioblastoma (GBM) is one of the most aggressive and lethal solid tumors in human. While efficacious therapeutics, such as emerging chimeric antigen receptor (CAR)-T cells and chemotherapeutics, have been developed to treat various cancers,
Externí odkaz:
https://doaj.org/article/6d014b190d954c29a0b1699c22696334
Publikováno v:
Platelets, Vol 33, Iss 5, Pp 692-699 (2022)
In vitro flow assays utilizing microfluidic devices are often used to study human platelets as an alternative to the costly animal models of hemostasis and thrombosis that may not accurately represent human platelet behavior in vivo. Here, we present
Externí odkaz:
https://doaj.org/article/5ee871f8f4cc4c6ca4daa984c9142d5a
Autor:
Mario Gutierrez, Mark Shamoun, Katie Giger Seu, Tyler Tanski, Theodosia A. Kalfa, Omolola Eniola-Adefeso
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract In this work, we utilized a parameterization model of ektacytometry to quantify the bulk rigidity of the rigid red blood cell (RBC) population in sickle cell disease (SCD) patients. Current ektacytometry techniques implement laser diffractio
Externí odkaz:
https://doaj.org/article/b60ad72e48f943938f60ea1c478716f4
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 1018 (2022)
Vascular-targeted carriers (VTCs) have the potential to localize therapeutics and imaging agents to inflamed, diseased sites. Poly (lactic-co-glycolic acid) (PLGA) is a negatively charged copolymer commonly used to construct VTCs due to its biodegrad
Externí odkaz:
https://doaj.org/article/71dc9c88b60f4894a00551bba8160e59
Autor:
Benjamin Czaja, Mario Gutierrez, Gábor Závodszky, David de Kanter, Alfons Hoekstra, Omolola Eniola-Adefeso
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 3, p e1007716 (2020)
The influence of red blood cell (RBC) deformability in whole blood on platelet margination is investigated using confocal microscopy measurements of flowing human blood and cell resolved blood flow simulations. Fluorescent platelet concentrations at
Externí odkaz:
https://doaj.org/article/935e186df4a544448cbc72d9918c65f3
Autor:
Gautam Sule, William J. Kelley, Srilakshmi Yalavarthi, Omolola Eniola-Adefeso, Jason S. Knight
Publikováno v:
Journal of Clinical and Translational Science, Vol 3, Pp 14-14 (2019)
OBJECTIVES/SPECIFIC AIMS: While the role of antiphospholipid antibodies in activating endothelial cells has been extensively studied, the impact of these antibodies on the adhesive potential of leukocytes has received considerably less attention. Mac
Externí odkaz:
https://doaj.org/article/ff14209086cd4b1b99dde8da47f2d835
Autor:
Daniel J Sobczynski, Phapanin Charoenphol, Michael J Heslinga, Peter J Onyskiw, Katawut Namdee, Alex J Thompson, Omolola Eniola-Adefeso
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107408 (2014)
The nanoscale plasma protein interaction with intravenously injected particulate carrier systems is known to modulate their organ distribution and clearance from the bloodstream. However, the role of this plasma protein interaction in prescribing the
Externí odkaz:
https://doaj.org/article/03b8e8b9f75e45af8e4b25ef077ed09a
Autor:
Ryan B Huang, Omolola Eniola-Adefeso
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31874 (2012)
BackgroundEndothelial cells (ECs) are continuously exposed to hemodynamic forces imparted by blood flow. While it is known that endothelial behavior can be influenced by cytokine activation or fluid shear, the combined effects of these two independen
Externí odkaz:
https://doaj.org/article/fc88ab988fca48c9b826d56508f81d2f
Autor:
Martin T. Spang, Ryan Middleton, Miranda Diaz, Jervaughn Hunter, Joshua Mesfin, Alison Banka, Holly Sullivan, Raymond Wang, Tori S. Lazerson, Saumya Bhatia, James Corbitt, Gavin D’Elia, Gerardo Sandoval-Gomez, Rebecca Kandell, Maria A. Vratsanos, Karthikeyan Gnanasekaran, Takayuki Kato, Sachiyo Igata, Colin Luo, Kent G. Osborn, Nathan C. Gianneschi, Omolola Eniola-Adefeso, Pedro Cabrales, Ester J. Kwon, Francisco Contijoch, Ryan R. Reeves, Anthony N. DeMaria, Karen L. Christman
Publikováno v:
Nature Biomedical Engineering. 7:94-109
Decellularized extracellular matrix in the form of patches and locally injected hydrogels has long been used as therapies in animal models of disease. Here we report the safety and feasibility of an intravascularly infused extracellular matrix as a b