Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Omkar B, Ijare"'
Autor:
Nourhan Abdelfattah, Parveen Kumar, Caiyi Wang, Jia-Shiun Leu, William F. Flynn, Ruli Gao, David S. Baskin, Kumar Pichumani, Omkar B. Ijare, Stephanie L. Wood, Suzanne Z. Powell, David L. Haviland, Brittany C. Parker Kerrigan, Frederick F. Lang, Sujit S. Prabhu, Kristin M. Huntoon, Wen Jiang, Betty Y. S. Kim, Joshy George, Kyuson Yun
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Glioblastoma (GBM) is an immune cold tumour that is refractory to immunotherapy. Here, the authors identify molecular phenotypes of immune-suppressive and -promoting myeloid cells in GBM through single cell RNA sequencing and propose S100A4 as a regu
Externí odkaz:
https://doaj.org/article/8729e15cfe464e098e0bc6e28aafb086
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Electromagnetic fields (EMF) raise intracellular levels of reactive oxygen species (ROS) that can be toxic to cancer cells. Because weak magnetic fields influence spin state pairing in redox-active radical electron pairs, we hypothesize that they dis
Externí odkaz:
https://doaj.org/article/94fb975157344b4393de38b79e10c8c6
Autor:
Wolfgang Bogner, Omkar B. Ijare, Martyn A. Sharpe, David S. Baskin, Santosh A. Helekar, Sophie Lopez, Fabio Henrique Brasil da Costa, Gilbert Hangel, Robert Bachoo, Shashank Hambarde, Kumar Pichumani, Georg Widhalm
Publikováno v:
Neuro Oncol
Background We postulate that meningiomas undergo distinct metabolic reprogramming in tumorigenesis and unraveling their metabolic phenotypes provide new therapeutic insights. Glutamine catabolism is key to the growth and proliferation of tumors. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff95e62a4c8077b8f8ad60febf17037
https://doi.org/10.1093/neuonc/noab219
https://doi.org/10.1093/neuonc/noab219
Autor:
Omkar B. Ijare, Santosh A. Helekar, Martyn A. Sharpe, David S. Baskin, Kumar Pichumani, Shashank Hambarde
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 147:3577-3589
The mechanisms underlying anticancer effects of electromagnetic fields are poorly understood. An alternating electric field-generating therapeutic device called Optune™ device has been approved for the treatment of glioblastoma (GBM). We have devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::714671e6e7db69658214a023c62ac517
https://doi.org/10.1007/s00432-021-03787-0
https://doi.org/10.1007/s00432-021-03787-0
Autor:
Nourhan Abdelfattah, Parveen Kumar, Caiyi Wang, Jia-Shiun Leu, William W. Flynn, Ruli Gao, David S. Baskin, Kumar Pichumani, Omkar B. Ijare, Stephanie Wood, Suzanne Powell, David Haviland, Frederick F. Lang, Sujit Prabhu, Kristin Huntoon, Brittany C. Parker Kerrigan, Wen Jiang Jiang, Betty Y. Kim, Joshy George, Kyuson Yun
Publikováno v:
Cancer Research. 82:2540-2540
Glioblastoma (GBM) is the most prevalent primary brain malignancy in adults. The current standard of care includes maximal surgical resection followed by radio- and chemotherapy with temozolomide. Yet Citation Format: Nourhan Abdelfattah, Parveen Kum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bd2e446b906c489195d2e381eda8ee8
https://doi.org/10.1158/1538-7445.am2022-2540
https://doi.org/10.1158/1538-7445.am2022-2540
Autor:
Jonathan Hebert, Cole Holan, Kumar Pichumani, David S. Baskin, Martyn A. Sharpe, Omkar B. Ijare
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
The diagnosis of various histological subtypes of pituitary tumors is made using serum based hormone panel test. However, certain subtypes secrete more than one hormone, making the diagnosis ambiguous. Here, we performed 1H-NMR based metabolomic anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce40379df4c607d4a600c82aceb4a383
http://link.springer.com/article/10.1038/s41598-020-58244-8
http://link.springer.com/article/10.1038/s41598-020-58244-8
Autor:
Santosh A, Helekar, Shashank, Hambarde, Omkar B, Ijare, Kumar, Pichumani, David S, Baskin, Martyn A, Sharpe
Publikováno v:
Journal of cancer research and clinical oncology. 147(12)
The mechanisms underlying anticancer effects of electromagnetic fields are poorly understood. An alternating electric field-generating therapeutic device called Optune™ device has been approved for the treatment of glioblastoma (GBM). We have devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f81a794db459c308012657768b18b116
https://pubmed.ncbi.nlm.nih.gov/34477946
https://pubmed.ncbi.nlm.nih.gov/34477946
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Pituitary adenomas (PAs) are benign growths arising from epithelial cells in the adenohypophysis of the pituitary gland. To date, there has been no detailed metabolic characterization of PAs of various subtypes. In this study, we report nuclear magne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b150d3cd4e5f9d9a735603e15ffc9b75
http://link.springer.com/article/10.1038/s41598-019-38542-6
http://link.springer.com/article/10.1038/s41598-019-38542-6
Autor:
Omkar B. Ijare, Alexandra M. Baskin, Brianna N. Baskin, Martyn A. Sharpe, Kumar Pichumani, David S. Baskin
Publikováno v:
Cancers
Volume 13
Issue 8
Cancers, Vol 13, Iss 1815, p 1815 (2021)
Volume 13
Issue 8
Cancers, Vol 13, Iss 1815, p 1815 (2021)
Simple Summary Proliferation of glioblastoma (GBM) depends on access to extracellular nutrients. Inadequate tumor perfusion creates a short supply of the most common nutrients, such as glucose (Glc) and glutamine. As a result, GBMs undergo metabolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f5c1e8085d88154b972e701ae39fb3b
Autor:
Nourhan, Abdelfattah, Parveen, Kumar, Caiyi, Wang, Jia-Shiun, Leu, William F, Flynn, Ruli, Gao, David S, Baskin, Kumar, Pichumani, Omkar B, Ijare, Stephanie L, Wood, Suzanne Z, Powell, David L, Haviland, Brittany C, Parker Kerrigan, Frederick F, Lang, Sujit S, Prabhu, Kristin M, Huntoon, Wen, Jiang, Betty Y S, Kim, Joshy, George, Kyuson, Yun
Publikováno v:
Nature communications. 13(1)
A major rate-limiting step in developing more effective immunotherapies for GBM is our inadequate understanding of the cellular complexity and the molecular heterogeneity of immune infiltrates in gliomas. Here, we report an integrated analysis of 201
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4401808d85f7b9e5644528ba794152b
https://pubmed.ncbi.nlm.nih.gov/35140215
https://pubmed.ncbi.nlm.nih.gov/35140215