Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Omidreza Firuzi"'
Autor:
Mohammad Hosein Sayahi, Bahareh Hassani, Maryam Mohammadi-Khanaposhtani, Navid Dastyafteh, Mohammad Reza Gohari, Mohammadreza Mohajeri Tehrani, Bagher Larijani, Mohammad Mahdavi, Omidreza Firuzi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract A new series of 2-amino-1,4-naphthoquinone-benzamides 5a-n was designed based on previously reported potent cytotoxic agents. These compounds were synthesized from the reaction of 1,4-naphthoquinone, 4-aminobenzoic acid, and appropriate amin
Externí odkaz:
https://doaj.org/article/8076120b24eb4b8190230698b5a80b7b
Autor:
Maryam Firouzi, Zahra Haghighijoo, Masoomeh Eskandari, Maryam Mohabbati, Ramin Miri, Mohammad Hasan Jamei, Alireza Poustforoosh, Somayeh Nazari, Omidreza Firuzi, Mehdi Khoshneviszadeh, Najmeh Edraki
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-16 (2024)
Abstract Two series of novel imidazo[1,2-a]pyridine-2-carbohydrazide derivatives have been designed, synthesized, and evaluated for cytotoxic activity. Target compounds were designed in two series: aryl hydrazone derivatives that were devoid of triaz
Externí odkaz:
https://doaj.org/article/b3857a4241ff4145bf0fa7257831487f
Autor:
Motahareh Mortazavi, Masoomeh Eskandari, Fatemeh Moosavi, Tahereh Damghani, Mehdi Khoshneviszadeh, Somayeh Pirhadi, Luciano Saso, Najmeh Edraki, Omidreza Firuzi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Oncogenic activation of receptor tyrosine kinases (RTKs) such as MET is associated with cancer initiation and progression. We designed and synthesized a new series of quinazoline derivatives bearing 1,2,3-triazole moiety as targeted anticanc
Externí odkaz:
https://doaj.org/article/c1443f8e9a85470f9474abe6d0ecf7b6
Autor:
Mina Saeedi, Aida Iraji, Yasaman Vahedi-Mazdabadi, Atiyeh Alizadeh, Najmeh Edraki, Omidreza Firuzi, Mahdieh Eftekhari, Tahmineh Akbarzadeh
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Cinnamomum verum J. Presl. (Lauraceae), Myrtus communis L. (Myrtaceae), Ruta graveolens L. (Rutaaceae), Anethum graveolens L. (Apiaceae), Myristica fragrans Houtt. (Myristicaceae), and Crocus sativus L. (Iridaceae) have been recom
Externí odkaz:
https://doaj.org/article/86a5b6f8cd8e46d4b73fdaa7cd3342c8
Autor:
Motahareh Mortazavi, Masoumeh Divar, Tahereh Damghani, Fatemeh Moosavi, Luciano Saso, Somayeh Pirhadi, Mehdi Khoshneviszadeh, Najmeh Edraki, Omidreza Firuzi
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
The advent of novel receptor tyrosine kinase inhibitors has provided an important therapeutic tool for cancer patients. In this study, a series of quinazolinone hydrazide triazole derivatives were designed and synthesized as novel MET (c-MET) recepto
Externí odkaz:
https://doaj.org/article/cf100fbfe3654206af7467a5ea561e43
Autor:
Tahereh Damghani, Fatemeh Moosavi, Mehdi Khoshneviszadeh, Motahareh Mortazavi, Somayeh Pirhadi, Zahra Kayani, Luciano Saso, Najmeh Edraki, Omidreza Firuzi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)
Abstract Aberrant activation of c-Met signalling plays a prominent role in cancer development and progression. A series of 12 imidazo [1,2-α] pyridine derivatives bearing 1,2,3-triazole moiety were designed, synthesized and evaluated for c-Met inhib
Externí odkaz:
https://doaj.org/article/e84ba50f01d64642a71fc85adbc1b611
Autor:
Fatemeh Heidary Jamebozorgi, Morteza Yousefzadi, Omidreza Firuzi, Melika Nazemi, Somayeh Zare, Jima N. Chandran, Bernd Schneider, Ian T. Baldwin, Amir Reza Jassbi
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 575-583 (2021)
Context Ircinia mutans Wilson (Irciniidae) is a sponge with antimicrobial and cytotoxic constituents. Objective Our objective was to characterise the cytotoxic constituents of two seasonal collections of I. mutans. Materials and methods The sponges w
Externí odkaz:
https://doaj.org/article/2b8ce94c77b7419f9a30d4cf09ed8ca7
Autor:
Hajar Karimi Askarani, Aida Iraji, Arezoo Rastegari, Syed Nasir Abbas Bukhari, Omidreza Firuzi, Tahmineh Akbarzadeh, Mina Saeedi
Publikováno v:
BMC Chemistry, Vol 14, Iss 1, Pp 1-13 (2020)
Abstract To discover multifunctional agents for the treatment of Alzheimer's disease (AD), a new series of 1,2,3-triazole-chromenone derivatives were designed and synthesized based on the multi target-directed ligands approach. The in vitro biologica
Externí odkaz:
https://doaj.org/article/3b7d0a77b06248d6b73f5fc662b21ba4
Autor:
Sara Ranjbar, Mohammad Reza Shabanpoor, Zahra Dehghani, Omidreza Firuzi, Najmeh Edraki, Mehdi Khoshneviszadeh
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 57 (2021)
Cathepsin B, an abundant expressed cysteine peptidase, plays a key role in cancer cell proliferation, tumor metastasis, apoptosis, angiogenesis, invasion and migration. Therefore, development of cathepsin B inhibitors to treat cancer is of great sign
Externí odkaz:
https://doaj.org/article/43af8306a5af4b6582977b4892da1566
Autor:
Mina Saeedi, Aida Iraji, Yasaman Vahedi-Mazdabadi, Atiyeh Alizadeh, Najmeh Edraki, Omidreza Firuzi, Mahdieh Eftekhari, Tahmineh Akbarzadeh
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 22, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/6e4db826627d4347951f8faf98635950