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pro vyhledávání: '"Omid M. Gulban"'
Autor:
Omid M. Gulban, Yoshihide Hayashizaki, Michael A. Quail, Paul A. Lyons, James K. Bonfield, John A. Todd, Jayne S. Danska, Jane Rogers, Robert L. Davies, Tim Hubbard, Bob Plumb, Jen Harrow, Thomas M. Keane, Charles A. Steward, Michael Nefedov, David J. Adams, Stephen Rice, Tony Cox, Matthew C. Jones, Linda S. Wicker, Pieter J. de Jong, Sean Humphray
Publikováno v:
Genomics
Non-obese diabetic (NOD) mice spontaneously develop type 1 diabetes (T1D) due to the progressive loss of insulin-secreting β-cells by an autoimmune driven process. NOD mice represent a valuable tool for studying the genetics of T1D and for evaluatin
Autor:
Omid M. Gulban, Charles A. Steward, Vinicius Motta, Jeremy Mogridge, Steven M. Mortin-Toth, Kuo Chien Liao, Jayne S. Danska, Janet Markle
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 194(12)
Type 1 diabetes in the NOD mouse model has been linked to >30 insulin-dependent diabetes (Idd) susceptibility loci. Idd4 on chromosome 11 consists of two subloci, Idd4.1 and Idd4.2. Using congenic analysis of alleles in NOD and NOD-resistant (NOR) mi
Autor:
Omid M. Gulban, Jayne S. Danska, Evgueni A. Ivakine, Aneta Valova, Angelo J. Canty, Steven M. Mortin-Toth, C.A. Scott
Publikováno v:
Diabetes. 55(12)
The nonobese diabetic (NOD) mouse recapitulates many aspects of the pathogenesis of type 1 diabetes in humans, including inheritance as a complex trait. More than 20 Idd loci have been linked to type 1 diabetes susceptibility in NOD mice. Previously,
Autor:
Omid M. Gulban, Steven M. Mortin-Toth, Ellen Wankiewicz, Jayne S. Danska, Angelo J. Canty, Evgueni A. Ivakine, C.A. Scott, David R. Spurrell
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 176(5)
High-resolution mapping and identification of the genes responsible for type 1 diabetes (T1D) has proved difficult because of the multigenic etiology and low penetrance of the disease phenotype in linkage studies. Mouse congenic strains have been use