Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Omer Mohamed Abdalla"'
Autor:
Achyut Adhikari, M. Ahmed Mesaik, Nayab Kanwal, Omer Mohamed Abdalla, Syed Ghulam Musharraf, Naveed Iqbal
Publikováno v:
Phytochemistry Letters. 14:203-208
Two new steroidal alkaloids, (20 S)-(bennzamido)-3β-(N,N-dimethyamino)-pregnane (1), and (20 S)-(bennzamido)-pregnane-3-one- (2), and two known steroidal alkaloids, pachysanaximine A (3) and 3β, 20α-diacetamido-5α-pregnane (4) were isolated from
Autor:
Achyut Adhikari, Syed Ghulam Musharraf, Naveed Iqbal, M. Ahmed Mesaik, Omer Mohamed Abdalla, Hamid Ali, Nurul Kabir
Publikováno v:
International Immunopharmacology. 28:235-243
Sarcococca saligna methanolic extract, fractions and isolated pure compounds saracocine (1), saracodine (2), pachyximine-A (3) and terminaline (4) were found to possess potent immunosuppressive activities. The fractions and compounds were tested in-v
Autor:
Sobia Ahsan Halim, M. Ahmed Mesaik, Omer Mohamed Abdalla, Maria Kontoyianni, Zaheer Ul-Haq, Abdul Wadood
Publikováno v:
Molecular Diversity. 17:345-355
Interleukin-2 (IL-2), is a 15.5-kDa cytokine that is now emerging as a target in drug discovery for novel therapeutic approaches in several autoimmune disorders. In an attempt to identify new inhibitors for the IL-2/IL-2R interaction, virtual screeni
Autor:
Abdul Majid Ayatollahi, Omer Mohamed Abdalla, Suleiman Afsharypour, M. Iqbal Choudhary, M. Ahmad Mesaik, Mustafa Ghanadian
Publikováno v:
Journal of Asian Natural Products Research. 15:22-29
Chloroform-acetone extract of the aerial parts of Euphorbia aellenii Rech. f. (Euphorbiaceae) was investigated for its diterpenoidal constituents. This led to the isolation of two new and one known cyclomyrsinol-type diterpenes 1-3. The structures we
Autor:
Suleiman Afsharypour, Syed Mustafa Ghanadian, M. Ahmed Mesaik, Omer Mohamed Abdalla, Mohammed Rabbani, Mohsen Shahlaei, Abdul Majid Ayatollahi
Publikováno v:
Medicinal Chemistry Research. 22:1795-1803
Currently, scientists are focused on developing drug-like compounds as an alternative to the available immunosuppressive drugs with less side effects. Therefore, in the current study we tried to generate derivatives of lupeol and investigate their pr
Autor:
Mohy El Din Abd El Fattah, Samreen Soomro, Almas Jabeen, Ahmed T. A. Boraei, El Sayed H. El Ashry, Beenish Fatima, Mohamed R. E. Aly, El Sayed H. El Tamany, Ahmed Shukrulla, Omer Mohamed Abdalla, M. Ahmed Mesaik
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 28:105-112
A series of S- and N-alkylated indolyloxadiazoles 2-7 were prepared. All compounds were tested for their immunomodulatory activity against T-cell proliferation, oxidative burst and cytokine analysis. Compounds 1, 2a, 2b, 2c and 2k demonstrated highly
Autor:
M. Ahmed Mesaik, Shahnaz Perveen, Wolfgang Voelter, Khalid Mohammed Khan, Fazal Rahim, Ahmed Shukralla Khalid, Syed Moazzam Haider, Muhammad Taha, Samreen Soomro, Omer Mohamed Abdalla
Publikováno v:
Bioorganic chemistry. 60
The synthetic indole Mannich bases 1-13 have been investigated for their ability to modulate immune responses measured in vitro. These activities were based on monitoring their affects on T-lymphocyte proliferation, reactive oxygen species (ROS), IL
Autor:
Johanna Raffetseder, Henrik Andersson, Sadaf Kalsum, Nadir Abuzeid, Marie Larsson, Elsje Pienaar, Mikaela Glader, Waleed S. Koko, Haidar A. AlGadir, Richin John Koshy, Maria Lerm, M. Ahmed Mesaik, Muddathir S. Alhassan, Thomas Schön, Omer Mohamed Abdalla, Asaad Khalid, Daniel Eklund
Publikováno v:
Journal of ethnopharmacology. 157
Ethnopharmacological relevance The emergence of multidrug-resistant strains of Mycobacterium tuberculosis underscores the need for continuous development of new and efficient methods to determine the susceptibility of isolates of Mycobacterium tuberc
Publikováno v:
Natural product research. 27(3)
Aceton: chloroform (1:2) extracts of the aerial parts of Euphorbia kopetdaghi Prokh. (Euphorbiaceae) were investigated for its diterpenoids and afforded three new five-membered ring, pentacyclic myrisinane polyester comprised of 3,5,10-O-triacetyl-8-
Autor:
Mohammad R. Amer, Omer Mohamed Abdalla, M. Ahmed Mesaik, Zaheer Ul-Haq, Samreen Soomro, Almas Jabeen, El Sayed H. El Ashry, Sobia Ahsan Halim, Aly A. Aly
Publikováno v:
Bioorganicmedicinal chemistry. 20(9)
The immunomodulating properties of functionalized [2-(arylamino)-4,4-dimethyl-6-oxo-cyclohex-1-ene] carbodithioates and 6,6-dimethyl-4-(2-(propan-2-ylidene)hydrazinyl)-6,7-dihydro-2H-indazole-3(5H)-thione compounds have been investigated. Four of the