Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Omer Donmez"'
Autor:
Tareian A Cazares, Faiz W Rizvi, Balaji Iyer, Xiaoting Chen, Michael Kotliar, Anthony T Bejjani, Joseph A Wayman, Omer Donmez, Benjamin Wronowski, Sreeja Parameswaran, Leah C Kottyan, Artem Barski, Matthew T Weirauch, V B Surya Prasath, Emily R Miraldi
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 1, p e1010863 (2023)
Transcription factors read the genome, fundamentally connecting DNA sequence to gene expression across diverse cell types. Determining how, where, and when TFs bind chromatin will advance our understanding of gene regulatory networks and cellular beh
Externí odkaz:
https://doaj.org/article/47ad65dfdd1a46f0b5c46cc8a247f53a
Autor:
Xiaoming Lu, Xiaoting Chen, Carmy Forney, Omer Donmez, Daniel Miller, Sreeja Parameswaran, Ted Hong, Yongbo Huang, Mario Pujato, Tareian Cazares, Emily R. Miraldi, John P. Ray, Carl G. de Boer, John B. Harley, Matthew T. Weirauch, Leah C. Kottyan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Thousands of genetic variants have been associated with lupus, but causal variants and mechanisms are unknown. Here, the authors combine a massively parallel reporter assay with genome-wide ChIP experiments to identify risk variants with allelic enha
Externí odkaz:
https://doaj.org/article/aad49cc516be41898af7df55bb543c1e
Autor:
Amy A Eapen, Sreeja Parameswaran, Carmy Forney, Lee E Edsall, Daniel Miller, Omer Donmez, Katelyn Dunn, Xiaoming Lu, Marissa Granitto, Hope Rowden, Adam Z Magier, Mario Pujato, Xiaoting Chen, Kenneth Kaufman, David I Bernstein, Ashley L Devonshire, Marc E Rothenberg, Matthew T Weirauch, Leah C Kottyan
Publikováno v:
PLoS Genetics, Vol 18, Iss 5, p e1009973 (2022)
Atopic dermatitis (AD) is one of the most common skin disorders among children. Disease etiology involves genetic and environmental factors, with 29 independent AD risk loci enriched for risk allele-dependent gene expression in the skin and CD4+ T ce
Externí odkaz:
https://doaj.org/article/5aaedcdbf87f4cd6875c58bb569fc698
Autor:
Matthew R Hass, Daniel Brissette, Sreeja Parameswaran, Mario Pujato, Omer Donmez, Leah C Kottyan, Matthew T Weirauch, Raphael Kopan
Publikováno v:
PLoS Genetics, Vol 17, Iss 6, p e1009574 (2021)
Runt-related transcription factor 1 (Runx1) can act as both an activator and a repressor. Here we show that CRISPR-mediated deletion of Runx1 in mouse metanephric mesenchyme-derived mK4 cells results in large-scale genome-wide changes to chromatin ac
Externí odkaz:
https://doaj.org/article/a61e659e34d045a0b33e892800ee2cb9
Autor:
Shemshat Kerimova, Omer Donmez, Mustafa Gunes, Furkan Kuruoglu, Mustafa Aydın, Cebrail Gumus, Ayse Erol
Publikováno v:
Materials Science and Engineering: B. 290:116349
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e631650c2fef3ceb4e837612045d578
https://doi.org/10.1016/j.mseb.2023.116349
https://doi.org/10.1016/j.mseb.2023.116349
Autor:
Omer Donmez, Mustafa Aydın, Selman Mutlu, Janne Puustinen, Joonas Hilska, Mircea Guina, Ayse Erol
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc08cbf33697bcbac3ebd0167c94ab70
https://doi.org/10.2139/ssrn.4157153
https://doi.org/10.2139/ssrn.4157153
Autor:
Omer Donmez, Mustafa Aydın, Selman Mutlu, Janne Puustinen, Joonas Hilska, Mircea Guina, Ayse Erol
Publikováno v:
Materials Science in Semiconductor Processing. 154:107227
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::209d6927f251f97dd50b141ec46163d1
https://doi.org/10.1016/j.mssp.2022.107227
https://doi.org/10.1016/j.mssp.2022.107227
Autor:
Amy A. Eapen, Sreeja Parameswaran, Carmy Forney, Lee E. Edsall, Daniel Miller, Omer Donmez, Katelyn Dunn, Xiaoming Lu, Marissa Granitto, Hope Rowden, Adam Z. Magier, Mario Pujato, Xiaoting Chen, Kenneth Kaufman, David I Bernstein, Ashley L. Devonshire, Marc E. Rothenberg, Matthew T. Weirauch, Leah Kottyan
Atopic dermatitis (AD) is one of the most common skin disorders in children. Disease etiology involves genetic and environmental factors, with the 29 independent AD risk loci enriched for risk allele-dependent gene expression in the skin and CD4+ T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5219fea294ab70e0be54f39546ad608d
https://doi.org/10.1101/2021.12.03.471059
https://doi.org/10.1101/2021.12.03.471059
Autor:
Carl G. de Boer, Carmy Forney, Matthew T. Weirauch, Emily R. Miraldi, Daniel Miller, Omer Donmez, Xiaoming Lu, Xiaoting Chen, John B. Harley, John P. Ray, Leah C. Kottyan, Mario Pujato, Ted Hong, Tareian Cazares, Yongbo Huang, Sreeja Parameswaran
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Genome-wide association studies of Systemic Lupus Erythematosus (SLE) nominate 3073 genetic variants at 91 risk loci. To systematically screen these variants for allelic transcriptional enhancer activity, we construct a massively parallel reporter as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab5b9ea43351f626b30f7f10bb029ea
https://doi.org/10.1038/s41467-021-21854-5
https://doi.org/10.1038/s41467-021-21854-5