Effects of plasma concentrations of 5-fluorouracil on long-term survival after treatment with a definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma

Autor: Nishiguchi Kohshi, Kadoyama Kaori, Yamamori Motohiro, Kuwahara Akiko, Nakamura Tsutomu, Miki Ikuya, Tamura Takao, Okuno Tatsuya, Omatsu Hideaki, Sakaeda Toshiyuki

Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 30, Iss 1, p 94 (2011)

Abstract Background A substantial body of literature has accumulated during the past 20 years showing the plasma concentrations of 5-fluorouracil (5-FU) to correlate with clinical response and/or toxicity in colorectal cancer, and head and neck cance

Externí odkaz: https://doaj.org/article/aef75011700a49d695fc6764e9837874

Induction of Human P-Glycoprotein in Caco-2 cells: Development of a Highly Sensitive Assay System for P-Glycoprotein-Mediated Drug Transport

Autor: Shirasaka, Yoshiyuki ^*, Kawasaki, Masae, Sakane, Toshiyasu, Omatsu, Hideaki, Moriya, Yuka, Nakamura, Tsutomu, Sakaeda, Toshiyuki, Okumura, Katsuhiko, Langguth, Peter, Yamashita, Shinji

Publikováno v: In Drug Metabolism and Pharmacokinetics 2006 21(5):414-423

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Differentially expressed genes throughout the cellular immortalization processes are quite different between normal human fibroblasts and endothelial cells.

Autor: Hiyama K; Department of Translational Cancer Research, Research Institute for Radiation Biology and Medicine, Hiroshima University, Minami-ku, Japan. khiyama@hiroshima-u.ac.jp, Otani K, Ohtaki M, Satoh K, Kumazaki T, Takahashi T, Mitsui Y, Okazaki Y, Hayashizaki Y, Omatsu H, Noguchi T, Tanimoto K, Nishiyama M

Publikováno v: International journal of oncology [Int J Oncol] 2005 Jul; Vol. 27 (1), pp. 87-95.