Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Omari J Bandele"'
Autor:
Maher A Noureddine, Daniel Menendez, Michelle R Campbell, Omari J Bandele, Monica M Horvath, Xuting Wang, Gary S Pittman, Brian N Chorley, Michael A Resnick, Douglas A Bell
Publikováno v:
PLoS Genetics, Vol 5, Iss 5, p e1000462 (2009)
The p53 tumor suppressor regulates its target genes through sequence-specific binding to DNA response elements (REs). Although numerous p53 REs are established, the thousands more identified by bioinformatics are not easily subjected to comparative f
Externí odkaz:
https://doaj.org/article/c25bbce90e3945b88637a8ae0d552b94
Publikováno v:
Nucleic Acids Research
p53 coordinates the expression of an intricate network of genes in response to stress signals. Sequence-specific DNA binding is essential for p53-mediated tumor suppression. We evaluated the impact of single-nucleotide polymorphisms (SNPs) in p53 res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73875b04a793af6b4f1756e5e39e94e0
https://doi.org/10.1093/nar/gkq764
https://doi.org/10.1093/nar/gkq764
Autor:
Neil Osheroff, Omari J. Bandele
Publikováno v:
Biochemistry. 47:11900-11908
Type II topoisomerases are enzymes that modulate the topological structure of DNA by generating transient double-stranded breaks in the backbone of the double helix (1-6). In order to maintain genomic integrity during this process, the enzymes form c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f89972761c5125473af7b3a0cc7384
https://doi.org/10.1021/bi800981j
https://doi.org/10.1021/bi800981j
Publikováno v:
Chemical Research in Toxicology. 21:1253-1260
Dietary polyphenols are a diverse and complex group of compounds that are linked to human health. Many of their effects have been attributed to the ability to poison (i.e., enhance DNA cleavage by) topoisomerase II. Polyphenols act against the enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900221669dd0df20c853d3cdae746882
https://doi.org/10.1021/tx8000785
https://doi.org/10.1021/tx8000785
Autor:
Omari J. Bandele, Neil Osheroff
Publikováno v:
Biochemistry. 46:6097-6108
Bioflavonoids are human dietary components that have been linked to the prevention of cancer in adults and the generation of specific types of leukemia in infants. While these compounds have a broad range of cellular activities, many of their genotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81a7805bbfb61b4feeeb78c1b087ce27
https://doi.org/10.1021/bi7000664
https://doi.org/10.1021/bi7000664
Autor:
Xuting Wang, Gary S. Pittman, Omari J. Bandele, Jason J. Bischof, Gang Liu, John F. Brothers, Avrum Spira, Douglas A. Bell
Publikováno v:
Human genetics. 133(12)
Chronic cigarette smoking exposes airway epithelial cells to thousands of carcinogens, oxidants and DNA damaging agents, creating a field of molecular injury in the airway and altering gene expression. Studies of cytologically normal bronchial epithe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7053eec63c248e14ccc2b71a82d40972
https://pubmed.ncbi.nlm.nih.gov/25179167
https://pubmed.ncbi.nlm.nih.gov/25179167
Autor:
Josiann Perron, Luc Gaudreau, Jean-François Millau, Douglas A. Bell, Éric F. Bouchard, Régen Drouin, Nathalie Bastien, Omari J. Bandele
Publikováno v:
Nucleic Acids Research
The p53 protein is crucial for adapting programs of gene expression in response to stress. Recently, we revealed that this occurs partly through the formation of stress-specific p53 binding patterns. However, the mechanisms that generate these bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a81ca69de40f7a508cf60cd968a82f3
https://pubmed.ncbi.nlm.nih.gov/21177650
https://pubmed.ncbi.nlm.nih.gov/21177650
Autor:
Douglas A. Bell, Brian N. Chorley, Michael A. Resnick, Maher A. Noureddine, Michelle R. Campbell, Gary S. Pittman, Monica M. Horvath, Daniel Menendez, Omari J. Bandele, Xuting Wang
Publikováno v:
PLoS Genetics, Vol 5, Iss 5, p e1000462 (2009)
PLoS Genetics
PLoS Genetics
The p53 tumor suppressor regulates its target genes through sequence-specific binding to DNA response elements (REs). Although numerous p53 REs are established, the thousands more identified by bioinformatics are not easily subjected to comparative f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe76948862e0c265f7519336f9f3793f
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19424414/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19424414/?tool=EBI
Autor:
Neil Osheroff, Omari J. Bandele
Publikováno v:
Methods in Molecular Biology ISBN: 9781607613398
Topoisomerase II is an essential enzyme that is required for a number of critical nuclear processes. All of the catalytic functions of topoisomerase II require the enzyme to generate a transient double-stranded break in the backbone of the double hel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eaf73566db177588437dbe39f39e12e
https://europepmc.org/articles/PMC2893727/
https://europepmc.org/articles/PMC2893727/
Autor:
Neil Osheroff, Omari J. Bandele
(-)-Epigallocatechin gallate (EGCG) is the most abundant and biologically active polyphenol in green tea, and many of the therapeutic benefits of the beverage have been attributed to this compound. High concentrations of EGCG are cytotoxic and trigge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::447ab0c3f76871046eb10145955b416f
https://europepmc.org/articles/PMC2893035/
https://europepmc.org/articles/PMC2893035/