Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Omar de Faria Junior"'
Autor:
Yusei Miyazaki, Rui Li, Ayman Rezk, Hétoum Misirliyan, Craig Moore, Nasr Farooqi, Mayra Solis, Lorna Galleguillos Goiry, Omar de Faria Junior, Van Duc Dang, David Colman, Ajit Singh Dhaunchak, Jack Antel, Jennifer Gommerman, Alexandre Prat, Simon Fillatreau, Amit Bar-Or, CIHR/MSSC New Emerging Team Grant in Clinical Autoimmunity, MSSRF Canadian B cells in MS Team
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105421 (2014)
Clinical trial results demonstrating that B-cell depletion substantially reduces new relapses in patients with multiple sclerosis (MS) have established that B cells play a role in the pathophysiology of MS relapses. The same treatment appears not to
Externí odkaz:
https://doaj.org/article/d0ba6ea0eb514d9ea1dbcb02442d3e4d
Autor:
Omar de Faria Junior, James Andrew Dixon, Jack P. Antel, Heidi M. McBride, Yun Hsuan Lin, Timothy E. Kennedy, Diane Sumie Nakamura
Publikováno v:
SSRN Electronic Journal.
Mitochondria produce energy and molecular precursors essential for myelin synthesis by oligodendrocytes. In multiple sclerosis, mitochondria become dysfunctional leaving oligodendrocytes more susceptible to oxidative damage than neurons. Despite such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b541a268ee3972b2d6102b412252dc30
https://doi.org/10.2139/ssrn.3420371
https://doi.org/10.2139/ssrn.3420371
Autor:
Marc Charabati, Nicolas Paradis-Isler, Omar de Faria Junior, Sienna S. Drake, Alyson E. Fournier, Camille A. Juźwik, Alexandre Prat, Aline Dumas, Craig S. Moore, Marc-André Lécuyer, Barbara Morquette, Stephanie Zandee, Dylan A. Galloway, Yang Zhang, Amit Bar-Or, Isabel Rambaldi, Mardja Bueno, Luc Vallières
Publikováno v:
Brain : a journal of neurology. 142(10)
Multiple sclerosis is a chronic inflammatory, demyelinating, and neurodegenerative disease affecting the brain, spinal cord and optic nerves. Neuronal damage is triggered by various harmful factors that engage diverse signalling cascades in neurons;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ef16cf3f6c3594fd34705967758e58
https://pubmed.ncbi.nlm.nih.gov/31412103
https://pubmed.ncbi.nlm.nih.gov/31412103
Autor:
Luc Vallières, Julia Zhang, Marc Charabati, Barbara Morquette, Camille A. Juźwik, Aline Dumas, Alexandre Prat, Dylan A. Galloway, Alyson E. Fournier, Amit Bar-Or, Sienna S. Drake, Craig S. Moore, Omar de Faria Junior, Isabel Rambaldi, Mardja Bueno, Marc-André Lécuyer
Multiple sclerosis (MS) is an autoimmune disease characterized by demyelination and neurodegeneration in the brain, spinal cord and optic nerve. Neuronal degeneration and death underlie progressive forms of MS and cognitive dysfunction. Neuronal dama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ff327c66d82e720b08d59181c77c30
Autor:
Ajit S. Dhaunchak, Alejandro D. Roth, Amit Bar-Or, Liliana Pedraza, Jack P. Antel, David R. Colman, Jeffrey K. Huang, Omar de Faria Junior
Publikováno v:
Glia. 58(16)
Compact myelin, the paranode, and the juxtaparanode are discrete domains that are formed on myelinated axons. In humans, neurological disorders associated with loss of myelin, including Multiple Sclerosis, often also result in disassembly of the node
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fde27d36fe5b8e8e3d1b815b1e52752
https://pubmed.ncbi.nlm.nih.gov/20830807
https://pubmed.ncbi.nlm.nih.gov/20830807