Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Omar Vélez-López"'
Autor:
Omar Vélez-López, Kelvin Carrasquillo-Carrión, Yadira M. Cantres-Rosario, Eraysy Machín-Martínez, Manuel E. Álvarez-Ríos, Abiel Roche-Lima, Eduardo L. Tosado-Rodríguez, Loyda M. Meléndez
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 1934 (2024)
HIV-1 infects monocyte-derived macrophages (MDM) that migrate into the brain and secrete virus and neurotoxic molecules, including cathepsin B (CATB), causing cognitive dysfunction. Cocaine potentiates CATB secretion and neurotoxicity in HIV-infected
Externí odkaz:
https://doaj.org/article/d244f6bbf6654cb6a256face6ac49479
Autor:
Annabell C. Segarra, María C. Andino Norat, Loyda M. Meléndez, Omar Vélez López, Manuel Álvarez, Richard L. Skolasky, Santhi Gorantla
Publikováno v:
Journal of Neuroimmune Pharmacology
Pathogenesis of HIV-associated neurocognitive disorders (HAND) is mediated through the infiltration of perivascular macrophages into the brain with the secretion of viral, neurotoxic and inflammatory proteins. One of these proteins is cathepsin B (CA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa72fcb214a42fd93ae7d190fbec8629
https://doi.org/10.1007/s11481-018-9807-4
https://doi.org/10.1007/s11481-018-9807-4