Avoidance of apoptotic death via a hyperploid salvage survival pathway after platinum treatment in high grade serous carcinoma cell line models

Autor: John M. S. Bartlett, Arian Khandani, Alexandra Wudwud, Oliver Fung, Omar Subedar, Mikhail Bashkurov, Andras Kapus, Blaise A. Clarke, Patricia Shaw, Robert Rottapel, Tony Yeung

Publikováno v: Oncotarget
Yeung, T, Fung, O, Bashkurov, M, Khandani, A, Subedar, O, Wudwud, A, Shaw, P, Clarke, B, Bartlett, J, Rottapel, R & Kapus, A 2019, ' Avoidance of apoptotic death via a hyperploid salvage survival pathway after platinum treatment in high grade serous carcinoma cell line models ', Oncotarget, vol. 10, no. 62, pp. 6691-6712 . https://doi.org/10.18632/oncotarget.27330
Scopus-Elsevier

The alkylating agent platinum is first-line chemotherapy treatment for high-grade serous carcinomas (HGSC) of tubal-ovarian origin. Platinum compounds cause DNA damage and induce apoptotic cell death in the bulk tumor population. However, subpopulati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f12923a6b294f39950f1ee33d68119
http://europepmc.org/articles/PMC6877103