Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Omar M E Albagha"'
Autor:
Jamil Alenbawi, Yasser A. Al-Sarraj, Umm-Kulthum I. Umlai, Ayat Kadhi, Nagham N. Hendi, Georges Nemer, Omar M. E. Albagha
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-12 (2024)
Abstract Sitosterolemia is a rare inherited disorder caused by mutations in the ABCG5/ABCG8 genes. These genes encode proteins involved in the transport of plant sterols. Mutations in these genes lead to decreased excretion of phytosterols, which can
Externí odkaz:
https://doaj.org/article/4b41350d245544dabc97274275caff03
Autor:
Asma A Elashi, Salman M Toor, Umm-Kulthum Ismail Umlai, Yasser A Al-Sarraj, Shahrad Taheri, Karsten Suhre, Abdul Badi Abou-Samra, Omar M E Albagha
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-12 (2024)
Abstract Background The genetic basis of type 2 diabetes (T2D) is under-investigated in the Middle East, despite the rapidly growing disease prevalence. We aimed to define the genetic determinants of T2D in Qatar. Methods Using whole genome sequencin
Externí odkaz:
https://doaj.org/article/c774abd0646240a2b405daad8348f9b2
Autor:
Usama Aliyu, Umm-Kulthum Ismail Umlai, Salman M. Toor, Asma A. Elashi, Yasser A. Al-Sarraj, Abdul Badi Abou−Samra, Karsten Suhre, Omar M. E. Albagha
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Insulin resistance (IR) and beta cell dysfunction are the major drivers of type 2 diabetes (T2D). Genome-Wide Association Studies (GWAS) on IR have been predominantly conducted in European populations, while Middle Eastern populations remain largely
Externí odkaz:
https://doaj.org/article/bc21fd641a684049950681181649ca07
Autor:
Yasser Al-Sarraj, Rowaida Z. Taha, Eman Al-Dous, Dina Ahram, Somayyeh Abbasi, Eman Abuazab, Hibah Shaath, Wesal Habbab, Khaoula Errafii, Yosra Bejaoui, Maryam AlMotawa, Namat Khattab, Yasmin Abu Aqel, Karim E. Shalaby, Amina Al-Ansari, Marios Kambouris, Adel Abouzohri, Iman Ghazal, Mohammed Tolfat, Fouad Alshaban, Hatem El-Shanti, Omar M. E. Albagha
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Introduction: Autism spectrum disorder (ASD) is characterized by aberrations in social interaction and communication associated with repetitive behaviors and interests, with strong clinical heterogeneity. Genetic factors play an important role in ASD
Externí odkaz:
https://doaj.org/article/1cb66fb1f0d64cfb9ab254e423381745
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background T2D is of high prevalence in the middle east and thus studying its mechanisms is of a significant importance. Using 1026 Qatar BioBank samples, epigenetics, whole genome sequencing and metabolomics were combined to further elucida
Externí odkaz:
https://doaj.org/article/dd40fe7719a44abc9ffe5f560a43e254
Autor:
Asma A Elashi, Salman M Toor, Umm-Kulthum Ismail Umlai, Yasser A. Al-Sarraj, Shahrad Taheri, Karsten Suhre, Abdul Badi Abou-Samra, Omar M. E. Albagha
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/3d7da35c5cfd40b79cb786a33c499a5f
Autor:
Ramesh Elango, Sameera Rashid, Radhakrishnan Vishnubalaji, Reem Al-Sarraf, Mohammed Akhtar, Khalid Ouararhni, Julie Decock, Omar M. E. Albagha, Nehad M. Alajez
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-14 (2023)
Abstract Previous studies have suggested that breast cancer (BC) from the Middle East and North Africa (MENA) is presented at younger age with advanced tumor stage, indicating underlying biological differences. Given the scant transcriptomic data on
Externí odkaz:
https://doaj.org/article/46de994f3f8943249fb29316d5144ad2
Autor:
Shaza B. Zaghlool, Anna Halama, Nisha Stephan, Valborg Gudmundsdottir, Vilmundur Gudnason, Lori L. Jennings, Manonanthini Thangam, Emma Ahlqvist, Rayaz A. Malik, Omar M. E. Albagha, Abdul Badi Abou‑Samra, Karsten Suhre
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Four T2D subtypes were previously identified: severe insulin deficient, severe insulin resistant, mild obesity-related, and mild age-related diabetes. Here, the authors show that these subtypes can be translated to an Arabic population and identify d
Externí odkaz:
https://doaj.org/article/024c4ed8cecf48589549684338878032
Autor:
Salman M. Toor, Eman K. Aldous, Aijaz Parray, Naveed Akhtar, Yasser Al-Sarraj, Essam M. Abdelalim, Abdelilah Arredouani, Omar El-Agnaf, Paul J. Thornalley, Sajitha V. Pananchikkal, Ghulam Jeelani Pir, Raheem Ayadathil Thazhhe Kuni, Ashfaq Shuaib, Nehad M. Alajez, Omar M. E. Albagha
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Stroke is the second leading cause of global mortality and continued efforts aim to identify predictive, diagnostic, or prognostic biomarkers to reduce the disease burden. Circulating microRNAs (miRNAs) have emerged as potential biomarkers in stroke.
Externí odkaz:
https://doaj.org/article/14182f8bb886419da0388089a89ec258
Autor:
Ilhame Diboun, Yasser Al-Sarraj, Salman M. Toor, Shaban Mohammed, Nadeem Qureshi, Moza S. H. Al Hail, Amin Jayyousi, Jassim Al Suwaidi, Omar M. E. Albagha
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Familial hypercholesterolemia (FH) is an inherited disease characterized by reduced efficiency of low-density lipoprotein-cholesterol (LDL-C) removal from the blood and, consequently, an increased risk of life-threatening early cardiovascular complic
Externí odkaz:
https://doaj.org/article/24e107776a2c4f2a8e333ab37ad49833