Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Omar M Beleh"'
Publikováno v:
Journal of the American Chemical Society. 145:9951-9958
Publikováno v:
J Am Chem Soc
The defined structure of molecules bearing multiple stereogenic axes is of increasing relevance to materials science, pharmaceuticals, and catalysis. However, catalytic enantioselective approaches to control multiple stereogenic axes remain synthetic
Autor:
Jie Gao, Skalitzky Donald James, Bing Yang, Junping Zhang, Charles A Lesch, Xiaolong Tian, Chenxi Qiao, Chad A. Van Huis, Clarke Taylor, Laura L. Carter, Tao Zheng, Weiping Zou, Rodney W. Morgan, Peter L. Toogood, Yahong Wang, Kellie Demock, Gary D. Glick, Xiao Hu, Jacques Moisan, Chrystal M. Paulos, JoAnn Scatina, Changxin Huo, Thomas Daniel Aicher, Alexander R. Hurd, Omar M Beleh, Ling-Yang Hao
Publikováno v:
Journal of medicinal chemistry. 64(18)
Retinoic acid receptor-related orphan receptor γ (RORc, RORγ, or NR1F3) is the nuclear receptor master transcription factor that drives the function and development of IL-17-producing T helper cells (Th17), cytotoxic T cells (Tc17), and subsets of
Autor:
Omar M. Beleh, Markus A. Seeliger, Kristoffer R. Brandvold, Taylor K. Johnson, Sameer Phadke, Jeanne A. Stuckey, Frank E. Kwarcinski, Matthew B. Soellner, Jennifer L. Meagher
Publikováno v:
ACS Chem Biol
In the kinase field, there are many widely held tenets about conformation-selective inhibitors that have yet to be validated using controlled experiments. We have designed, synthesized, and characterized a series of kinase inhibitor analogues of dasa