A clinical perspective on muscle specific kinase antibody positive myasthenia gravis

Autor: Omar Keritam, Angela Vincent, Fritz Zimprich, Hakan Cetin

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

The discovery of autoantibodies directed against muscle-specific kinase (MuSK) in “seronegative” myasthenia gravis (MG) patients marked a milestone in MG research. In healthy muscle, MuSK regulates a phosphorylation pathway, which is essential fo

Externí odkaz: https://doaj.org/article/52c1ca63120c45dda5b9d36536fcee5f

Determination of Extravasation Effects of Nal-Iri and Trabectedin and Evaluation of Treatment Options for Trabectedin Extravasation in a Preclinical Animal Model

Autor: Omar Keritam, Viktoria Juhasz, Christian Schöfer, Christiane Thallinger, Marie-Bernadette Aretin, Gernot Schabbauer, Johannes Breuss, Matthias Unseld, Pavel Uhrin

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Background: Extravasation during chemotherapy administration can lead to dangerous adverse effects ranging from pain to tissue necrosis. Evidence-based data about prevention and treatment of extravasation injuries of some clinically used compounds st

Externí odkaz: https://doaj.org/article/40ce816895b94bfa9a70ea06deb5326f

Clinico‐genetic spectrum of limb‐girdle muscular weakness in Austria: A multicentre cohort study

Autor: Martin Krenn, Matthias Tomschik, Matias Wagner, Gudrun Zulehner, Rosa Weng, Jakob Rath, Sigrid Klotz, Ellen Gelpi, Gabriel Bsteh, Omar Keritam, Isabella Colonna, Chiara Paternostro, Fiona Jäger, Elisabeth Lindeck‐Pozza, Stephan Iglseder, Susanne Grinzinger, Martina Schönfelder, Christina Hohenwarter, Manfred Freimüller, Norbert Embacher, Julia Wanschitz, Raffi Topakian, Ana Töpf, Volker Straub, Stefan Quasthoff, Fritz Zimprich, Wolfgang N. Löscher, Hakan Cetin

Publikováno v: Eur. J. Neurol. 29, 1815-1824 (2022)

Hereditary myopathies with limb-girdle muscular weakness (LGW) are a genetically heterogeneous group of disorders, in which molecular diagnosis remains challenging. Our aim was to present a detailed clinical and genetic characterization of a large co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69fd628f4b40ca99a78490f29f9ef5c
https://doi.org/10.1111/ene.15306

The HSD17B13:TA (rs72613567) splice variant protects against severity of non-alcoholic fatty liver disease but not fibrosis

Autor: M. Trauner, P Munda, Stefan Traussnigg, Omar Keritam, Peter Ferenci, Judith Stift, Rafael Paternostro, Gerald W. Prager, Emina Halilbasic, Katharina Staufer, AF Stättermayer

Publikováno v: Zeitschrift für Gastroenterologie.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::abaa812c1433e160ff58be0fee23ddb6
https://doi.org/10.1055/s-0039-1691910

Clinical heterogeneity within the ALS‐FTD spectrum in a family with a homozygous optineurin mutation.

Autor: Parvizi, Tandis^1,2 (AUTHOR), Klotz, Sigrid^2,3 (AUTHOR), Keritam, Omar^1,2 (AUTHOR), Caliskan, Haluk¹ (AUTHOR), Imhof, Sophie^1,2 (AUTHOR), König, Theresa^1,2 (AUTHOR), Haider, Lukas^4,5 (AUTHOR), Traub‐Weidinger, Tatjana⁶ (AUTHOR), Wagner, Matias^7,8 (AUTHOR), Brunet, Theresa^8,9 (AUTHOR), Brugger, Melanie⁸ (AUTHOR), Zimprich, Alexander^1,2 (AUTHOR), Rath, Jakob^1,2 (AUTHOR), Stögmann, Elisabeth^1,2 (AUTHOR), Gelpi, Ellen^2,3 (AUTHOR) ellen.gelpi@meduniwien.ac.at, Cetin, Hakan^1,2 (AUTHOR) hakan.cetin@meduniwien.ac.at

Publikováno v: Annals of Clinical & Translational Neurology. Jun2024, Vol. 11 Issue 6, p1579-1589. 11p.