Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Omar K. Sial"'
Autor:
Astrid M. Cardona-Acosta, Omar K. Sial, Lyonna F. Parise, Tamara Gnecco, Giselle Enriquez Marti, Carlos A. Bolaños-Guzmán
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Increased use of benzodiazepines in adolescents have been reported, with alprazolam (ALP) being the most abused. Drug abuse during adolescence can induce changes with lasting consequences. This study investigated the neurobiological conseque
Externí odkaz:
https://doaj.org/article/47b1e9c9e84b44a29d3fbe166c3f5c79
Publikováno v:
Chronic Stress, Vol 6 (2022)
Background Individuals who experience emotional, physical, or sexual abuse as children suffer from higher rates of major depressive disorder, drug abuse, and suicide. Early life interventions such as peer support groups can be beneficial to adolescen
Externí odkaz:
https://doaj.org/article/2b663c5a40e14f468cdf5d93e6d71713
Autor:
Omar K. Sial, Tamara Gnecco, Astrid M. Cardona-Acosta, Emily Vieregg, Ernesto A. Cardoso, Lyonna F. Parise, Carlos A. Bolaños-Guzmán
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
A dramatic increase in the prevalence of major depression and diet-related disorders in adolescents has been observed over several decades, yet the mechanisms underlying this comorbidity have only recently begun to be elucidated. Exposure to western-
Externí odkaz:
https://doaj.org/article/1abac8781ffc453fbcb155efa80501aa
Autor:
Carley R Sattler, Omar K. Sial, Brandon L. Warren, Lyonna F. Parise, Eric M. Parise, Jacqueline C. Duperrouzel, Carlos A. Bolaños-Guzmán
Publikováno v:
Psychopharmacology (Berl)
Early life stress influences adult psychopathology and is associated with an increase in the propensity for drug use/seeking throughout the lifespan. Animal models corroborate that stress exposure exacerbates maladaptive reactivity to stressful stimu
Autor:
Lyonna F. Parise, Emily Vieregg, Ernesto A Cardoso, Tamara Gnecco, Omar K. Sial, Carlos A. Bolaños-Guzmán, Astrid M. Cardona-Acosta
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience
Frontiers in Neuroscience
A dramatic increase in the prevalence of major depression and diet-related disorders in adolescents has been observed over several decades, yet the mechanisms underlying this comorbidity have only recently begun to be elucidated. Exposure to western-
Autor:
Nycole Maza, Dandan Wang, Cody Kowalski, Hannah M. Stoveken, Maria Dao, Omar K. Sial, Andrew C. Giles, Brock Grill, Kirill A. Martemyanov
Publikováno v:
Nat Neurosci
Repeated exposure to opioids causes tolerance, which limits their analgesic utility and contributes to overdose and abuse liability. However, the molecular mechanisms underpinning tolerance are not well understood. Here, we used a forward genetic scr
Autor:
Barbara Juarez, Astrid M. Cardona-Acosta, Ming-Hu Han, Eric M. Parise, Trevonn M. Gyles, Dipesh Chaudhury, Eric J. Nestler, Carlos A. Bolaños-Guzmán, Omar K. Sial, Lyonna F. Parise
Publikováno v:
Biol Psychiatry
Background Major depressive disorder is prevalent in children and adolescents and is associated with a high degree of morbidity throughout life, with potentially devastating personal consequences and public health impact. The efficacy of ketamine (KE
Publikováno v:
Behav Brain Res
Two decades ago, the observation of a rapid and sustained antidepressant response after ketamine administration provided an exciting new avenue in the search for more effective therapeutics for the treatment of clinical depression. Research elucidati
Autor:
Lyonna F. Alcantara, Carlos A. Bolaños-Guzmán, Kyle G. Kroeck, Brandon L. Warren, Roey Hadad, Sergio D. Iñiguez, Omar K. Sial, Katherine N. Wright, Eric M. Parise
Publikováno v:
Biological Psychiatry. 74:750-759
Background Major depressive disorder afflicts up to 10% of adolescents. However, nearly 50% of those afflicted are considered nonresponsive to available treatments. Ketamine, a noncompetitive N -methyl-D-aspartate receptor antagonist has shown potent
Autor:
Lyonna F. Alcantara, Carlos A. Bolaños-Guzmán, Brandon L. Warren, Eric M. Parise, Omar K. Sial
Publikováno v:
Journal of neuroscience methods. 258
Background Animal models capable of differentiating the neurobiological intricacies between physical and emotional stress are scarce. Current models rely primarily on physical stressors (e.g., chronic unpredictable or mild stress, social defeat, lear