Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Omar J. Michel"'
Autor:
Walter Paulus, Ankie Poutsma, Pieter Koolwijk, Marie van Dijk, Omar J. Michel, Cees B.M. Oudejans, Anouk Bokslag, Joyce Mulders, Tessa Nauta, Allerdien Visser, Andreas de Haas, Christianne J.M. de Groot
Publikováno v:
Oudejans, C, Poutsma, A, Michel, O, Mulders, J, Visser, A, van Dijk, M, Nauta, T, Bokslag, A, Paulus, W, de Haas, A, Koolwijk, P & de Groot, C J M 2016, ' Genome-Wide Identification of Epigenetic Hotspots Potentially Related to Cardiovascular Risk in Adult Women after a Complicated Pregnancy ', PLoS ONE, vol. 11, no. 2, e0148313 . https://doi.org/10.1371/journal.pone.0148313
PLoS ONE, Vol 11, Iss 2, p e0148313 (2016)
PLoS ONE
PLoS ONE, 11(2):e0148313. Public Library of Science
PLoS ONE, Vol 11, Iss 2, p e0148313 (2016)
PLoS ONE
PLoS ONE, 11(2):e0148313. Public Library of Science
Background The physiological demands of pregnancy on the maternal cardiovascular system can catapult women into a metabolic syndrome that predisposes to atherosclerosis in later life. We sought to identify the nature of the epigenomic changes associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18829e7886090caa02b99e3816625585
https://research.vumc.nl/en/publications/2a2953b6-04b9-446c-ac5f-cb94e335de77
https://research.vumc.nl/en/publications/2a2953b6-04b9-446c-ac5f-cb94e335de77
Autor:
Joyce Mulders, Marie van Dijk, Daoud Sie, Hari K. Thulluru, Ankie Poutsma, Gunilla Kleiverda, Omar J. Michel, Cees B.M. Oudejans, Augusta M. A. Lachmeijer, Sandra Windhorst
Publikováno v:
van Dijk, M, Thulluru, H K, Mulders, J, Michel, O J, Poutsma, A, Windhorst, S, Kleiverda, G, Sie, D L S, Lachmeijer, A M A & Oudejans, C B M 2012, ' HELLP babies link a novel lincRNA to the trophoblast cell cycle ', Journal of Clinical Investigation, vol. 122, no. 11, pp. 4003-4011 . https://doi.org/10.1172/JCI65171
Journal of Clinical Investigation, 122(11), 4003-4011. The American Society for Clinical Investigation
Journal of Clinical Investigation, 122(11), 4003-4011. The American Society for Clinical Investigation
The HELLP syndrome is a pregnancy-associated disease inducing hemolysis, elevated liver enzymes, and low platelets in the mother. Although the HELLP symptoms occur in the third trimester in the mother, the origin of the disease can be found in the fi
Autor:
Ankie Poutsma, Marjan M. Weiss, Marie van Dijk, Rob Janssen, Erik A. Sistermans, Omar J. Michel, Danny Incarnato, Gunilla Kleiverda, Cees B.M. Oudejans, Rob Habets, Salvatore Oliviero, Reynir Arngrímsson
Publikováno v:
Oudejans, C B M, Michel, O J, Janssen, R, Habets, R, Poutsma, A, Sistermans, E A, Weiss, M M, Incarnato, D, Oliviero, S, Kleiverda, G, van Dijk, M & Arngrimsson, R 2015, ' Susceptibility allele-specific loss of miR-1324-mediated silencing of the INO80B chromatin-assembly complex gene in pre-eclampsia ', Human Molecular Genetics, vol. 24, no. 1, pp. 118-127 . https://doi.org/10.1093/hmg/ddu423
Human Molecular Genetics, 24(1), 118-127. Oxford University Press
Human Molecular Genetics, 24(1), 118-127. Oxford University Press
In humans, the elucidation of the genetics underlying multifactorial diseases such as pre-eclampsia remains complex. Given the current day availability of genome-wide linkage- and expression data pools, we applied pathway-guided genome-wide meta-anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3525953b19ca67512f46c684413685e
https://research.vumc.nl/en/publications/44f793d4-cc9d-4491-a8ed-3809ff40a527
https://research.vumc.nl/en/publications/44f793d4-cc9d-4491-a8ed-3809ff40a527
Publikováno v:
Placenta, 36(4), 345-349. W.B. Saunders Ltd
Thulluru, H K, Michel, O J, Oudejans, C B M & van Dijk, M 2015, ' ACVR2A promoter polymorphism rs1424954 in the Activin-A signaling pathway in trophoblasts ', Placenta, vol. 36, no. 4, pp. 345-349 . https://doi.org/10.1016/j.placenta.2015.01.010
Thulluru, H K, Michel, O J, Oudejans, C B M & van Dijk, M 2015, ' ACVR2A promoter polymorphism rs1424954 in the Activin-A signaling pathway in trophoblasts ', Placenta, vol. 36, no. 4, pp. 345-349 . https://doi.org/10.1016/j.placenta.2015.01.010
Introduction Pre-eclampsia is a pregnancy-specific disorder and characterized by reduced trophoblast invasion and reduced spiral artery remodeling in the first trimester placenta. A polymorphism located in the promoter region of ACVR2A (rs1424954 (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6b41371435d54de721505c636d5e95
https://research.vumc.nl/en/publications/03a95c81-cebd-459a-bb5a-e746c09808a5
https://research.vumc.nl/en/publications/03a95c81-cebd-459a-bb5a-e746c09808a5
Publikováno v:
Placenta. 45:108
Autor:
Marie van Dijk, Omar J. Michel, Cees B.M. Oudejans, Daan van Abel, R. Veerhuis, Marlies Jacobs
Publikováno v:
Journal of Alzheimer's Disease, 31(4), 793-800. IOS Press
van Abel, D, Michel, O, Veerhuis, R, Jacobs, M, van Dijk, M & Oudejans, C B M 2012, ' Direct Downregulation of CNTNAP2 by STOX1A is Associated with Alzheimer's Disease ', Journal of Alzheimer's Disease, vol. 31, no. 4, pp. 793-800 . https://doi.org/10.3233/JAD-2012-120472
van Abel, D, Michel, O, Veerhuis, R, Jacobs, M, van Dijk, M & Oudejans, C B M 2012, ' Direct Downregulation of CNTNAP2 by STOX1A is Associated with Alzheimer's Disease ', Journal of Alzheimer's Disease, vol. 31, no. 4, pp. 793-800 . https://doi.org/10.3233/JAD-2012-120472
STOX1A is a transcription factor which is functionally and structurally similar to the forkhead box protein family. STOX1A has been shown to be associated with pre-eclampsia, a pregnancy associated disease, and to have potential implications in late
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749bbd5931a2c2ea5f58a4bdcc2bfc87
https://research.vumc.nl/en/publications/a2fd90f2-0af1-40d9-862d-e946b58d0f82
https://research.vumc.nl/en/publications/a2fd90f2-0af1-40d9-862d-e946b58d0f82