Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Omar Hajji"'
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 18, Iss 4, Pp 329-334 (2017)
Background: The ATM gene encoding a large protein kinase is mutated in ataxia-telangiectasia (AT), an autosomale recessive disease characterized by neurological and immunological symptoms, and cancer predisposition. Previous studies suggest that hete
Externí odkaz:
https://doaj.org/article/e91f4587d37649188264be1a8caacedb
Autor:
Kari Hemminki, Sellama Nadifi, Chaymaa Marouf, Stella Göhler, Asta Försti, Miguel Inacio da Silva Filho, Omar Hajji
Publikováno v:
BMC Cancer
Background Breast cancer (BC) is the most prevalent cancer in women and a major public health problem in Morocco. Several Moroccan studies have focused on studying this disease, but more are needed, especially at the genetic and molecular levels. The
Autor:
Hassan Jouhadi, Chaymaa Marouf, Amal Tazzite, Sellama Nadifi, Brehima Diakite, Omar Hajji, Abdellatif Benider
Publikováno v:
SpringerPlus
Purpose The cell-cycle checkpoint kinase 2 (CHEK2) is an important signal transducer of cellular responses to DNA damage, whose defects has been associated with increased risk for breast cancer. The CHEK2 1100delC mutation has been reported to confer