Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Omar Francone"'
Autor:
Hugo E. Tobar, Luis R. Cataldo, Trinidad González, Ricardo Rodríguez, Valentina Serrano, Antonio Arteaga, Ana Álvarez-Mercado, Carlos F. Lagos, Lucas Vicuña, José P. Miranda, Ana Pereira, Carolina Bravo, Concepción M. Aguilera, Susana Eyheramendy, Ricardo Uauy, Álvaro Martínez, Ángel Gil, Omar Francone, Attilio Rigotti, José L. Santos
Publikováno v:
Lipids in Health and Disease, Vol 18, Iss 1, Pp 1-10 (2019)
Abstract Background Lecithin-cholesterol acyltransferase (LCAT) is a plasma enzyme that esterifies cholesterol in high- and low-density lipoproteins (HDL and LDL). Mutations in LCAT gene causes familial LCAT deficiency, which is characterized by very
Externí odkaz:
https://doaj.org/article/08593db270244f0995b5209d4d00e7b3
Autor:
Huei-Mei Chen, Rachel Resendes, Azita Ghodssi, Danielle Sookiasian, Michael Tian, Serena Dollive, Laura Adamson-Small, Nancy Avila, Cagdas Tazearslan, John F Thompson, Jeff L Ellsworth, Omar Francone, Albert Seymour, Jason B Wright
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233373 (2020)
Targeted gene integration via precise homologous recombination (HR)-based gene editing has the potential to correct genetic diseases. AAV (adeno-associated virus) can mediate nuclease-free gene integration at a disease-causing locus. Therapeutic appl
Externí odkaz:
https://doaj.org/article/f8a88c5666bb403d9b0cc2f575ccb6c7
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 3, Pp 428-437 (2002)
Previous studies have indicated that LCAT may play a role in the generation of cholesteryl esters (CE) in plasma apolipoprotein B (apoB) lipoproteins. The purpose of the present study was to examine the quantitative importance of LCAT on apoB lipopro
Externí odkaz:
https://doaj.org/article/b538bedb04524c2f9eabf8e04bfd3607
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 10, Pp 1626-1635 (2001)
We have previously identified a single amino acid mutation (hE149A) in human LCAT that increases its in vitro reactivity with phosphatidylcholine species containing sn-2 arachidonate (Wang et al. 1997. J. Biol. Chem. 272: 280–286). The purpose of t
Externí odkaz:
https://doaj.org/article/144c722941194bf2afea53f30d2b51d9
Autor:
Jacinthe Gingras, Thia St Martin, Katie Gall, Jennifer Newman, Donald E. Selby, Samuel Adjei, Terrence Hanscom, Jaime Prout, Dariusz S. Przybylski, Alice Zheng, Nancy Avila, Jason Lotterhand, Israel Rivas, Teresa Wright, Omar Francone, Albert Seymour
Publikováno v:
Molecular Genetics and Metabolism. 138:107112
Autor:
Tania Seabrook, Kruti Patel, Laura J. Smith, Thia St-Martin, Liana Behmoiras, Monicah Kivaa, Katherine Gall, Meghan Scarpatti, Lindsay Schulman, Victor Zhivich, Minglun Wang, Daisy Huynh, Jeffrey Ellsworth, Jingyan Zhao, Shiva Krupa, Omar Francone, Albert Seymour, Jacinthe Gingras
Publikováno v:
Molecular Genetics and Metabolism. 135:S110