Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Omar F, Khan"'
Publikováno v:
Current Oncology, Vol 29, Iss 7, Pp 4768-4778 (2022)
Breast cancer is the most commonly diagnosed malignancy in women, with triple-negative breast cancer (TNBC) accounting for 10–20% of cases. Historically, fewer treatment options have existed for this subtype of breast cancer, with cytotoxic chemoth
Externí odkaz:
https://doaj.org/article/c9a000f787dd4429a3b60d1fee6d1067
Autor:
Omar F. Khan, Ellen Cusano, Soundouss Raissouni, Mica Pabia, Johanna Haeseker, Nicholas Bosma, Jenny J. Ko, Haocheng Li, Aalok Kumar, Michael M. Vickers, Patricia A. Tang
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Cognitive impairment is commonly reported in patients receiving chemotherapy, but the acuity of onset is not known. This study utilized the psychomotor vigilance test (PVT) and trail-making test B (TMT-B) to assess cognitive impai
Externí odkaz:
https://doaj.org/article/3f4fb44aa70342b4bd91d45cea37b857
Autor:
Grayson Tilstra, Julien Couture-Senécal, Yan Ming Anson Lau, Alanna M. Manning, Daniel S. M. Wong, Wanda W. Janaeska, Titobioluwa A. Wuraola, Janice Pang, Omar F. Khan
Publikováno v:
Journal of the American Chemical Society. 145:2294-2304
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::792bdec38f6456e08d34a8637ca9db06
https://doi.org/10.1021/jacs.2c10670
https://doi.org/10.1021/jacs.2c10670
Autor:
Malia McAvoy, Joshua C. Doloff, Omar F. Khan, Joseph Rosen, Robert Langer, Daniel G. Anderson
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
The success of devices delivering functional electrical stimulation (FES) has been hindered by complications related to implants including skin breakdown and subsequent wound dehiscence. Our hypothesis was that a vascularized muscle flap along the do
Externí odkaz:
https://doaj.org/article/fad17336c5584ea5918b2b0032798660
Autor:
Michael J. Mitchell, Jamie Webster, Amanda Chung, Pedro P. G. Guimarães, Omar F. Khan, Robert Langer
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Fluid shear stress plays a critical role in receptor-mediated signalling and has been shown to sensitize cancer cells to apoptosis. Here, Mitchellet al. introduce polymer micro- and nanoparticles tethered to tumour cells to amplify fluid shear stress
Externí odkaz:
https://doaj.org/article/d730205456884197a323e8fe7afb2487
Autor:
Jasdave S. Chahal, Tao Fang, Andrew W. Woodham, Omar F. Khan, Jingjing Ling, Daniel G. Anderson, Hidde L. Ploegh
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract The Zika virus (ZIKV) outbreak in the Americas and South Pacific poses a significant burden on human health because of ZIKV’s neurotropic effects in the course of fetal development. Vaccine candidates against ZIKV are coming online, but im
Externí odkaz:
https://doaj.org/article/f7a59228dbcc45f49fb90892d8c11545
Autor:
Shriya Srinivasan, Keval Vyas, Malia McAvoy, Peter Calvaresi, Omar F. Khan, Robert Langer, Daniel G. Anderson, Hugh Herr
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Given the increasing use of regenerative free muscle flaps for various reconstructive procedures and neuroprosthetic applications, there is great interest and value in their enhanced regeneration, revascularization, and reinnervation for improved fun
Externí odkaz:
https://doaj.org/article/3b48da6d42f44d73879378ac533bc5f9
Autor:
RaeAnna Wilson, Cristina Espinosa-Diez, Nathan Kanner, Namita Chatterjee, Rebecca Ruhl, Christina Hipfinger, Sunil J. Advani, Jie Li, Omar F. Khan, Aleksandra Franovic, Sara M. Weis, Sushil Kumar, Lisa M. Coussens, Daniel G. Anderson, Clark C. Chen, David A. Cheresh, Sudarshan Anand
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
The tumour microenvironment can be modulated to sensitize tumours to the effects of therapy. Here the authors show that radiation induced miR-103 downregulates TREX1 in endothelial cells, decreases angiogenesis and leads to the secretion of proinflam
Externí odkaz:
https://doaj.org/article/a01c9f15bea14236bb83264f01ebc409
Autor:
Irinna Papangeli, Jongmin Kim, Inna Maier, Saejeong Park, Aram Lee, Yujung Kang, Keiichiro Tanaka, Omar F. Khan, Hyekyung Ju, Yoko Kojima, Kristy Red-Horse, Daniel G. Anderson, Arndt F. Siekmann, Hyung J. Chun
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
G protein-coupled receptors APLNR and CXCR4 are crucial for vascular development. Here, the authors show that these two signaling pathways communicate and that in response to blood flow APLNR signaling induces a decrease in CXCR4 expression via miR-1
Externí odkaz:
https://doaj.org/article/f8d99b3209af438b97ff65e526d3b632
Autor:
Kevin White, Yu Lu, Sofia Annis, Andrew E Hale, B Nelson Chau, James E Dahlman, Craig Hemann, Alexander R Opotowsky, Sara O Vargas, Ivan Rosas, Mark A Perrella, Juan C Osorio, Kathleen J Haley, Brian B Graham, Rahul Kumar, Rajan Saggar, Rajeev Saggar, W Dean Wallace, David J Ross, Omar F Khan, Andrew Bader, Bernadette R Gochuico, Majed Matar, Kevin Polach, Nicolai M Johannessen, Haydn M Prosser, Daniel G Anderson, Robert Langer, Jay L Zweier, Laurence A Bindoff, David Systrom, Aaron B Waxman, Richard C Jin, Stephen Y Chan
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 6, Pp 695-713 (2015)
Abstract Iron–sulfur (Fe‐S) clusters are essential for mitochondrial metabolism, but their regulation in pulmonary hypertension (PH) remains enigmatic. We demonstrate that alterations of the miR‐210‐ISCU1/2 axis cause Fe‐S deficiencies in v
Externí odkaz:
https://doaj.org/article/2ba2fa97eac5474ab7e2db24f409a724