Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Omar Abou Saada"'
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-27 (2021)
Abstract While genome sequencing and assembly are now routine, we do not have a full, precise picture of polyploid genomes. No existing polyploid phasing method provides accurate and contiguous haplotype predictions. We developed nPhase, a ploidy agn
Externí odkaz:
https://doaj.org/article/7af772ca27eb4665b8c30bce5f0d8b8d
Autor:
Emilien Peltier, Charlotte Vion, Omar Abou Saada, Anne Friedrich, Joseph Schacherer, Philippe Marullo
Publikováno v:
Frontiers in Fungal Biology, Vol 2 (2021)
The identification of natural allelic variations controlling quantitative traits could contribute to decipher metabolic adaptation mechanisms within different populations of the same species. Such variations could result from human-mediated selection
Externí odkaz:
https://doaj.org/article/5c4b230e3b334fca8ba0473ca382b0ea
Publikováno v:
eLife, Vol 8 (2019)
Genome-wide association studies (GWAS) allow to dissect complex traits and map genetic variants, which often explain relatively little of the heritability. One potential reason is the preponderance of undetected low-frequency variants. To increase th
Externí odkaz:
https://doaj.org/article/6aaf094c83824bf79f7af9647f9f8e55
Autor:
Samuel O’Donnell, Jia-Xing Yue, Omar Abou Saada, Nicolas Agier, Claudia Caradec, Thomas Cokelaer, Matteo De Chiara, Stéphane Delmas, Fabien Dutreux, Téo Fournier, Anne Friedrich, Etienne Kornobis, Jing Li, Zepu Miao, Lorenzo Tattini, Joseph Schacherer, Gianni Liti, Gilles Fischer
SUMMARYAs population genomics is transitioning from single reference genomes to pangenomes, major improvements in terms of genome contiguity, phylogenetic sampling, haplotype phasing and structural variant (SV) calling are required. Here, we generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fc9e59e202c5bd192e653daf3d837ec
https://doi.org/10.1101/2022.10.04.510633
https://doi.org/10.1101/2022.10.04.510633
Publikováno v:
Genome Research
Genome Research, 2021, 31 (12), pp.2316-2326. ⟨10.1101/gr.275380.121⟩
Genome Res
Genome Research, 2021, 31 (12), pp.2316-2326. ⟨10.1101/gr.275380.121⟩
Genome Res
Polyploidization events are observed across the tree of life and occur in many fungi, plant, and animal species. During evolution, polyploidy is thought to be an important source of speciation and tumorigenesis. However, the origin of polyploid popul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87a3ed0aa0cefce0d6c8b65e6b3375a
https://hal.inrae.fr/hal-03545955/file/2021-Eberlein.pdf
https://hal.inrae.fr/hal-03545955/file/2021-Eberlein.pdf
Publikováno v:
Genomics. 114(3)
Phasing, and in particular polyploid phasing, have been challenging problems held back by the limited read length of high-throughput short read sequencing methods which can't overcome the distance between heterozygous sites and labor high cost of alt
Autor:
Omar Abou Saada, Andreas Tsouris, Chris Large, Anne Friedrich, Maitreya J. Dunham, Joseph Schacherer
Publikováno v:
Current Biology. 32:1350-1361.e3
Yeasts, and in particular Saccharomyces cerevisiae, have been used for brewing beer for thousands of years. Population genomic surveys highlighted that beer yeasts are polyphyletic, with the emergence of different domesticated subpopulations characte
While genome sequencing and assembly are now routine, we still do not have a full and precise picture of polyploid genomes. Phasing these genomes, i.e. deducing haplotypes from genomic data, remains a challenge. Despite numerous attempts, no existing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e00193d2af1244b7fab0a60ab91a34cd
https://doi.org/10.1101/2020.07.24.219105
https://doi.org/10.1101/2020.07.24.219105
Autor:
Omar Abou Saada, Moreno-Habel Da, Yoichi Toyokawa, Maitreya J. Dunham, Andreas Tsouris, Preiss R, McConnellogue H, Noah A. Hanson, Hiroshi Takagi, Schmidlin T, Jirasin Koonthongkaew, Large Crl, Joseph Schacherer
Ale brewing yeast are the result of admixture between diverse strains ofSaccharomyces cerevisiae, resulting in a heterozygous tetraploid that has since undergone numerous genomic rearrangements. As a result, comparisons between the genomes of modern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::718cae969f61140143227b649b77fcd3
https://doi.org/10.1101/2020.06.26.166157
https://doi.org/10.1101/2020.06.26.166157