Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Omar, de Faria"'
Autor:
Helena Pivoňková, Sergey Sitnikov, Yasmine Kamen, An Vanhaesebrouck, Moritz Matthey, Sonia Olivia Spitzer, Yan Ting Ng, Chenyue Tao, Omar de Faria, Jr., Balazs Viktor Varga, Ragnhildur Thóra Káradóttir
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114873- (2024)
Summary: Oligodendrocyte precursor cells (OPCs) generate myelinating oligodendrocytes and are the main proliferative cells in the adult central nervous system. OPCs are a heterogeneous population, with proliferation and differentiation capacity varyi
Externí odkaz:
https://doaj.org/article/0d65a74473834585b61377c365526130
Autor:
Yasmine Kamen, Kimberley Anne Evans, Sergey Sitnikov, Sonia Olivia Spitzer, Omar de Faria, Mert Yucel, Ragnhildur Thóra Káradóttir
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract In the central nervous system, oligodendrocyte precursor cells (OPCs) proliferate and differentiate into myelinating oligodendrocytes throughout life, allowing for ongoing myelination and myelin repair. With age, differentiation efficacy dec
Externí odkaz:
https://doaj.org/article/5cdd2304d6d44fcfbf53b010079547e3
Autor:
Sebastian Timmler, Helena Pivonkova, Balazs V. Varga, Kimberley A. Evans, Ragnhildur Thóra Káradóttir, Omar de Faria
Publikováno v:
Nature Neuroscience. 24:1508-1521
Myelin, a lipid membrane that wraps axons, enabling fast neurotransmission and metabolic support to axons, is conventionally thought of as a static structure that is set early in development. However, recent evidence indicates that in the central ner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61612daf5a189873c70254fc833230a3
https://doi.org/10.1038/s41593-021-00917-2
https://doi.org/10.1038/s41593-021-00917-2
Akademický článek
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Autor:
Yusei Miyazaki, Rui Li, Ayman Rezk, Hétoum Misirliyan, Craig Moore, Nasr Farooqi, Mayra Solis, Lorna Galleguillos Goiry, Omar de Faria Junior, Van Duc Dang, David Colman, Ajit Singh Dhaunchak, Jack Antel, Jennifer Gommerman, Alexandre Prat, Simon Fillatreau, Amit Bar-Or, CIHR/MSSC New Emerging Team Grant in Clinical Autoimmunity, MSSRF Canadian B cells in MS Team
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105421 (2014)
Clinical trial results demonstrating that B-cell depletion substantially reduces new relapses in patients with multiple sclerosis (MS) have established that B cells play a role in the pathophysiology of MS relapses. The same treatment appears not to
Externí odkaz:
https://doaj.org/article/d0ba6ea0eb514d9ea1dbcb02442d3e4d
Autor:
Omar, de Faria, Helena, Pivonkova, Balazs, Varga, Sebastian, Timmler, Kimberley Anne, Evans, Ragnhildur Thóra, Káradóttir
Publikováno v:
Nature neuroscience. 24(11)
Myelin, a lipid membrane that wraps axons, enabling fast neurotransmission and metabolic support to axons, is conventionally thought of as a static structure that is set early in development. However, recent evidence indicates that in the central ner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ba88956d0f0474b7a3149c33e212944
https://pubmed.ncbi.nlm.nih.gov/34711959
https://pubmed.ncbi.nlm.nih.gov/34711959
Autor:
Doyeun Kim, Samuel Clemot, Abbas F. Sadikot, Susan L. Ackerman, Edwin W. Wong, Omar de Faria, Diane S. Nakamura, Roland Pilgram, Timothy E. Kennedy, Mihai Victor Mocanu, Jenea M. Bin, Amir Shmuel
Netrins are secreted proteins that direct cell migration and axon extension in the developing CNS and are essential for normal neural development. In the mature CNS, netrin-1 is expressed by neurons and oligodendrocytes and implicated in the stabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb0b1227e438b2e2f56983ece6d60ed9
https://doi.org/10.1101/2020.08.06.234906
https://doi.org/10.1101/2020.08.06.234906
Publikováno v:
Journal of Neurochemistry
Myelin, the multilayered membrane surrounding many axons in the nervous system, increases the speed by which electrical signals travel along axons and facilitates neuronal communication between distant regions of the nervous system. However, how neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd69ac7b29152d9ce6190703171b11ba
https://doi.org/10.1111/jnc.14592
https://doi.org/10.1111/jnc.14592
Autor:
Kimberley A. Evans, Ragnhildur Thóra Káradóttir, Omar de Faria, Ewa Anastazia Claudia Pama, A. Luzhynskaya
Publikováno v:
Developmental Neurobiology. 78:93-107
The CNS is extremely responsive to an ever-changing environment. Studies of neural circuit plasticity focus almost exclusively on functional and structural changes of neuronal synapses. In recent years, however, myelin plasticity has emerged as a pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::472169c62c5986e38f95058b89ea4045
https://doi.org/10.1002/dneu.22539
https://doi.org/10.1002/dneu.22539
Autor:
Omar de Faria, Damla Khan, Jean-David Gothié, Heidi M. McBride, Yun Hsuan Lin, Jack P. Antel, James Andrew Dixon, Timothy E. Kennedy, Diane S. Nakamura
Publikováno v:
GliaREFERENCES. 69(2)
Mitochondria are dynamic organelles that produce energy and molecular precursors that are essential for myelin synthesis. Unlike in neurons, mitochondria in oligodendrocytes increase intracellular movement in response to glutamatergic activation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf65c4d42179780584c129e9977823f0
https://pubmed.ncbi.nlm.nih.gov/32910475
https://pubmed.ncbi.nlm.nih.gov/32910475