Výsledky vyhledávání - "Omar, Lozano"

Akademický článek

Bioprospection of rattlesnake venom peptide fractions with anti-adipose and anti-insulin resistance activity in vitro

Autor: David Meléndez-Martínez, Erika Ortega-Hernández, Edwin Estefan Reza-Zaldívar, Alejandro Carbajal-Saucedo, Gustavo Arnaud-Franco, Ana Gatica-Colima, Luis Fernando Plenge-Tellechea, Marilena Antunes-Ricardo, Daniel A. Jacobo-Velázquez, Karla Mayolo-Deloisa, Omar Lozano, Marco Rito-Palomares, Jorge Benavides

Publikováno v: Toxicon: X, Vol 24, Iss , Pp 100209- (2024)

Animal venoms are natural products that have served as a source of novel molecules that have inspired novel drugs for several diseases, including for metabolic diseases such as type-2 diabetes and obesity. From venoms, toxins such as exendin-4 (Helod

Externí odkaz: https://doaj.org/article/4954f2d9a4744a718097a89fbafba981

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Akademický článek

Previous cardiovascular injury is a prerequisite for immune checkpoint inhibitor‐associated lethal myocarditis in mice

Autor: Nestor Rubio‐Infante, Elena Cristina Castillo, Hugo Alves‐Figueiredo, Martin Ramos‐González, Felipe Salazar‐Ramírez, Daniel Salas‐Treviño, Adolfo Soto‐Domínguez, Omar Lozano, Gerardo García‐Rivas, Guillermo Torre‐Amione

Publikováno v: ESC Heart Failure, Vol 11, Iss 2, Pp 1249-1257 (2024)

Abstract Aims Immune checkpoint inhibitors (ICIs) are antineoplastic drugs designed to activate the immune system's response against cancer cells. Evidence suggests that they may lead to immune‐related adverse events, particularly when combined (e.

Externí odkaz: https://doaj.org/article/a73fc44d8437499999922c4692b270e3

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Akademický článek

Advances in Light-Responsive Smart Multifunctional Nanofibers: Implications for Targeted Drug Delivery and Cancer Therapy

Autor: Ahmed M. Agiba, Nihal Elsayyad, Hala N. ElShagea, Mahmoud A. Metwalli, Amin Orash Mahmoudsalehi, Saeed Beigi-Boroujeni, Omar Lozano, Alan Aguirre-Soto, Jose Luis Arreola-Ramirez, Patricia Segura-Medina, Raghda Rabe Hamed

Publikováno v: Pharmaceutics, Vol 16, Iss 8, p 1017 (2024)

Over the last decade, scientists have shifted their focus to the development of smart carriers for the delivery of chemotherapeutics in order to overcome the problems associated with traditional chemotherapy, such as poor aqueous solubility and bioav

Externí odkaz: https://doaj.org/article/d98a3a422ff84260b811b7e9e1235747

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Akademický článek

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Akademický článek

Amorphous SiO2 nanoparticles promote cardiac dysfunction via the opening of the mitochondrial permeability transition pore in rat heart and human cardiomyocytes

Autor: Omar Lozano, Christian Silva-Platas, Héctor Chapoy-Villanueva, Baruc E. Pérez, Jarmon G. Lees, Chrishan J. A. Ramachandra, Flavio F. Contreras-Torres, Anay Lázaro-Alfaro, Estefanía Luna-Figueroa, Judith Bernal-Ramírez, Aldemar Gordillo-Galeano, Alfredo Benitez, Yuriana Oropeza-Almazán, Elena C. Castillo, Poh Ling Koh, Derek J. Hausenloy, Shiang Y. Lim, Gerardo García-Rivas

Publikováno v: Particle and Fibre Toxicology, Vol 17, Iss 1, Pp 1-16 (2020)

Abstract Background Silica nanoparticles (nanoSiO2) are promising systems that can deliver biologically active compounds to tissues such as the heart in a controllable manner. However, cardiac toxicity induced by nanoSiO2 has been recently related to

Externí odkaz: https://doaj.org/article/abb9fd431a344e3fa835135d83431615

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Akademický článek

A Systematic Review of the Mechanisms Involved in Immune Checkpoint Inhibitors Cardiotoxicity and Challenges to Improve Clinical Safety

Autor: Nestor Rubio-Infante, Yoel Adbel Ramírez-Flores, Elena Cristina Castillo, Omar Lozano, Gerardo García-Rivas, Guillermo Torre-Amione

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that block CTLA-4, PD-1, or PD-L1 and induce the activation of the immune system against cancer. Despite the efficacy of ICIs, which has improved the oncotherapy for patients with a variet

Externí odkaz: https://doaj.org/article/231882cb6f2d407680131544773c5223

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Akademický článek

Subchronic exposure to titanium dioxide nanoparticles modifies cardiac structure and performance in spontaneously hypertensive rats

Publikováno v: Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-18 (2019)

Abstract Background Non-communicable diseases, intended as the results of a combination of inherited, environmental and biological factors, kill 40 million people each year, equivalent to roughly 70% of all premature deaths globally. The possibility

Externí odkaz: https://doaj.org/article/ffd873d7d1bf46f0840221599f35a53f

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