Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Omar, Jawdat"'
Autor:
Omar Jawdat, Jason Rucker, Tomoki Nakano, Kotaro Takeno, Jeffery Statland, Mamatha Pasnoor, Mazen M. Dimachkie, Carla Sabus, Yomna Badawi, Suzanne L. Hunt, Naoko H. Tomioka, Sumedha Gunewardena, Clark Bloomer, Heather M. Wilkins, Laura Herbelin, Richard J. Barohn, Hiroshi Nishimune
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) patients lack effective treatments to maintain motor and neuromuscular function. This study aimed to evaluate the effect of a home-based exercise program on muscle strength, ALS scores, and transcriptome i
Externí odkaz:
https://doaj.org/article/e3237184e1bb4c6f98062c0787594ebf
Autor:
Steven Perrin, Shafeeq Ladha, Nicholas Maragakis, Michael H Rivner, Jonathan Katz, Angela Genge, Nicholas Olney, Dale Lange, Daragh Heitzman, Cynthia Bodkin, Omar Jawdat, Namita A Goyal, Jeffrey D Bornstein, Carmen Mak, Stanley H Appel, Sabrina Paganoni
Publikováno v:
PLoS Medicine, Vol 21, Iss 10, p e1004469 (2024)
BackgroundThe interaction of CD40L and its receptor CD40 on activated T cells and B cells respectively control pro-inflammatory activation in the pathophysiology of autoimmunity and transplant rejection. Previous studies have implicated signaling pat
Externí odkaz:
https://doaj.org/article/bfaf649e6f014ac693adbf9dd52386e8
Autor:
Alexandra R. Brown, Byron J. Gajewski, Dinesh Pal Mudaranthakam, Mamatha Pasnoor, Mazen M. Dimachkie, Omar Jawdat, Laura Herbelin, Matthew S. Mayo, Richard J. Barohn
Publikováno v:
Contemporary Clinical Trials Communications, Vol 36, Iss , Pp 101220- (2023)
Background: Response adaptive randomization is popular in adaptive trial designs, but the literature detailing its execution is lacking. These designs are desirable for patients/stakeholders, particularly in comparative effectiveness research, due to
Externí odkaz:
https://doaj.org/article/b52e6d82e8a64ea2a96d8818dd50de39
Autor:
Sudheer K. Tungtur, Heather M. Wilkins, Robert S. Rogers, Yomna Badawi, Jessica M. Sage, Abdulbaki Agbas, Omar Jawdat, Richard J. Barohn, Russell H. Swerdlow, Hiroshi Nishimune
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Amyotrophic lateral sclerosis (ALS) remains a devastating motor neuron disease with limited treatment options. Oxaloacetate treatment has a neuroprotective effect in rodent models of seizure and neurodegeneration. Therefore, we treated the A
Externí odkaz:
https://doaj.org/article/38dec4f7c64841b98b4be34960b67c6f
Autor:
Alex G. Karanevich, Luke J. Weisbrod, Omar Jawdat, Richard J. Barohn, Byron J. Gajewski, Jianghua He, Jeffrey M. Statland
Publikováno v:
BMC Neurology, Vol 18, Iss 1, Pp 1-7 (2018)
Abstract Background To assess the feasibility of using automated capture of Electronic Medical Record (EMR) data to build predictive models for amyotrophic lateral sclerosis (ALS) outcomes. Methods We used an Informatics for Integrating Biology and t
Externí odkaz:
https://doaj.org/article/4e6a36e0d80343fca800074767fe6433
Autor:
Rasha Moussallem, Omar Jawdat, Duaa Jabari, Mamatha Pasnoor, Mazen Dimachkie, Jeffery Statland
Publikováno v:
Sunday, April 23.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76a26f8d99c2ef4fa304042f5209272d
https://doi.org/10.1212/wnl.0000000000204005
https://doi.org/10.1212/wnl.0000000000204005
Autor:
Swathy Chandrashekhar, Anai C. Hamasaki, Rebecca Clay, Ayla McCalley, Laura Herbelin, Mamatha Pasnoor, Omar Jawdat, Mazen M. Dimachkie, Richard J. Barohn, Jeffrey Statland
Publikováno v:
Muscle Nerve
INTRODUCTION/AIMS: Neuronal hyperexcitability (manifested by cramps) plays a pathological role in amyotrophic lateral sclerosis (ALS), and drugs affecting it may help symptomatic management and slow disease progression. We aimed to determine safety a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1044b76121d143949d50f49a2f4c5644
https://doi.org/10.1002/mus.27560
https://doi.org/10.1002/mus.27560
Autor:
Panying Rong, Omar Jawdat
Publikováno v:
Clinical Neurophysiology. 132:94-103
Objective To identify a novel physiologic marker of bulbar motor involvement in amyotrophic lateral sclerosis (ALS) based on jaw muscle synergies. Methods Muscle synergies were extracted from the surface electromyographic recordings of five jaw muscl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b587f34d76ecda0b466cbfee97147c3b
https://doi.org/10.1016/j.clinph.2020.09.030
https://doi.org/10.1016/j.clinph.2020.09.030
Autor:
Timothy R, Fullam, Swathy, Chandrashekhar, Constantine, Farmakidis, Omar, Jawdat, Mamatha, Pasnoor, Mazen M, Dimachkie, Jeffrey M, Statland
Publikováno v:
Musclenerve. 66(2)
Consistency of differences between non-dystrophic myotonias over time measured by standardized clinical/patient-reported outcomes is lacking. Evaluation of longitudinal data could establish clinically relevant endpoints for future research.Data from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cf75605a1a0e7cffea530c468cf8a6
https://pubmed.ncbi.nlm.nih.gov/35644941
https://pubmed.ncbi.nlm.nih.gov/35644941
Autor:
Richard J. Barohn, Omar Jawdat, Melanie Glenn, Sandra Camelo-Piragua, Barbara Distad, Mazen M. Dimachkie, Anai Hamasaki, Ryan Jacobson, Laura Herbelin, Mamatha Pasnoor, Andrew Heim, Michael D. Weiss, Gary Gallagher, Jeffrey Statland
Publikováno v:
RRNMF Neuromuscular Journal. 1:28-32
Introduction: Amyloid myopathy is a rare presentation of systemic amyloidosis. Amyloid myopathy can be initially misdiagnosed as sporadic inclusion body myositis (IBM). Methods: We report 4 cases of amyloid myopathy clinically mimicking inclusion bod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4371cd115da9ce58a927582d5dd3ce1
https://doi.org/10.17161/rrnmf.v1i4.13699
https://doi.org/10.17161/rrnmf.v1i4.13699