Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Om Parkash Suri"'
Autor:
Kunal Nepali, Mukunda Sudhakar Rao Bande, Vikas Thakur, Preet Mohinder Singh Bedi, Jyotsna Suri, Rohit Goyal, Ramji Das Budhiraja, Om Parkash Suri, Kanaya Lal Dhar
Publikováno v:
Medicinal Chemistry Research. 21:4158-4167
In the present study, the antiasthmatic activity of a 7,8,9,10-tetrahydro azepino[2,1-b]-quinazolin-12(6H)-one (TAZQ) and established mucolytic agent ambroxol, alone and in combination, in ovalbumin induced asthma in guinea pigs. TAZQ turned to be a
Autor:
Raj Kumar, Tandeep Kour, Kanahya Lal Dhar, Surrinder Koul, Manish K. Gupta, Sameer Sapra, Ajit Kumar Saxena, Sunil Kumar, Om Parkash Suri
Publikováno v:
Medicinal Chemistry Research. 21:3720-3729
This study is based on the synthesis of a series of combretastatin analogs with different substitutions on one aryl moiety and a carboxylic group in connecting chain. Cis-configuration with respect to aryl groups was established by X-ray crystal anal
Autor:
Raj Kumar, Amit Agarwal, Manish K. Gupta, Kunal Nepali, Sameer Sapra, Naresh Kumar Satti, Om Parkash Suri, Vineet Mittal, Kanaya Lal Dhar, Uttam Chand Banerjee
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:5569-5576
A series of forty two N-(1,3-diaryl-3-oxopropyl)amides were synthesized via an efficient, modified Dakin-West reaction and were evaluated for in vitro xanthine oxidase inhibitory activity for the first time. Structure-activity relationship analyses h
Autor:
Kunal Nepali, Abhishek Budhiraja, Vikas Aggarwal, Om Parkash Suri, Mandeep Kaur, Kanika Kadian, K. L. Dhar, Atul Garg, Sameer Sapra
Publikováno v:
Medicinal Chemistry Research. 21:2133-2140
Chalcone is an aromatic ketone that forms the central core for a variety of important biological compounds, which are collectively known as chalcones. These show antibacterial, antifungal, antitumour and anti-inflammatory properties, and also are int
Autor:
Rohit Goyal, Sameer Sapra, Atul Garg, Sunil Kumar, Kanaya Lal Dhar, Punita Sharma, Om Parkash Suri, Mukunda Sudhakar Rao Bande, Naresh Kumar Satti, Kunal Nepali
Publikováno v:
Medicinal Chemistry Research. 21:1271-1277
A series of azepino[2,1-b]quinazolones (C-1–C-16) have been synthesized and evaluated for their antitussive activity using citric acid-induced cough model in Guinea pigs. The compounds C-1–C-16 caused notable decrease in cough frequency and incre
Autor:
Prashant Singh Chauhan, Punita Sharma, Kanaya Lal Dhar, Prabhu Dutt, Naresh Kumar Satti, Vivek K. Gupta, Musarat Amina, Om Parkash Suri, Deepak Sharma, Bishan Datt Gupta, Krishan Avtar Suri
Publikováno v:
Steroids. 76:358-364
A new steroidal sapogenin molecule 1 having unique characteristics, 21-nor and unusual C19 carboxylic acid has been isolated from the roots of Asparagus racemosus. On the basis of chemical evidence, extensive spectroscopic analysis including two dime
Autor:
Sameer Sapra, Kunal Nepali, Om Parkash Suri, Kanaya Lal Dhar, Naveen Kumar, Raj Kumar, Krishna Reddy V. Bijjem
Publikováno v:
Medicinal Chemistry Research. 21:531-537
Aromatic vapors of monoterpenoids such as menthol and camphor are known to possess antitussive effects for the symptomatic relief of upper respiratory tract. The lactams 10 and 11 of menthol and camphor, respectively, have been synthesised and evalua
Autor:
B. B. Singh, Naresh Kumar Satti, Om Parkash Suri, K. A. Suri, Neelam Sharma, Vikram Bhardwaj, V. N. Gupta, B. D. Gupta, B.K. Chandan
Publikováno v:
Phytotherapy Research. 20:831-839
The bioassay guided fractionation of the dried aerial part of Indigofera tinctoria Linn. led to the identification of an active fraction labelled as indigotin. On further chemical analysis, a compound isolated from indigotin was identified and charac
Autor:
S. C. Puri, A.K. Kalsotra, Abdul S. Shawl, Om Parkash Suri, Gulam Nabi Qazi, G. Handa, Vinay Gupta
Publikováno v:
Journal of Chromatographic Science. 44:177-180
St. John's Wort (Hypericum perforatum), a perennial flowering plant, has been used medicinally for thousands of years and has most recently been identified as an effective treatment for mild to moderate depression and neuralgic disorders. This work p
Autor:
B. D. Gupta, M.S. Youssouf, G.D. Singh, Gulam Nabi Qazi, A. Zabeer, Om Parkash Suri, Kanaya Lal Dhar, Naresh Kumar Satti, Gupta Op, K. A. Suri, Asha Bhagat
Publikováno v:
European Journal of Medicinal Chemistry. 41:429-434
Taking lead from a naturally occurring quinazolin vasicine, a number of compounds were developed and evaluated for bronchodilator and anti-allergic activities. One of these compounds was 2,4-diethoxy-6,7,8,9,10,12-hexahydroazepino[2,1-b]quinazolin-12