Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Oluyomi A. Okunola"'
Autor:
Muzamil Olamide Hassan, Fatiu Abiola Arogundade, Stephen Adebayo Osasan, Babajide A Gbadegesin, Bolanle Aderonke Omotoso, Oluyomi Oluseun Okunola, Abubakr Abefe Sanusi, Kayode A Adelusola, Norah O Akinola, Adewale Akinsola
Publikováno v:
Nigerian Postgraduate Medical Journal, Vol 31, Iss 1, Pp 53-61 (2024)
Background: Improvements in sickle cell disease (SCD) care have resulted in the survival of many patients into adulthood, although this is accompanied by the increased incidence of end-organ damage, including chronic kidney disease (CKD). Objectives:
Externí odkaz:
https://doaj.org/article/ac70990060274cf1a8de3635b23b41e3
Autor:
Ayoola Odeyemi, Adeola O. Ajibare, Olalekan E. Ojo, Oluwafemi T. Ojo, Boma Paul-Odo, Oluyomi O. Okunola, Fatiu A. Arogundade, Abubakr A. Sanusi
Publikováno v:
Journal of Advances in Medicine and Medical Research. :247-254
Introduction: Sickle cell disease (SCD) is a common cause of Chronic kidney disease (CKD) and microalbuminuria is a predictor of CKD. Aims: To determine the prevalence of microalbuminuria (MA) in SCD patients as well as the clinical correlates of MA
Autor:
Olutoyin Morenike Lawal, Michael Olabode Balogun, Anthony Olubunmi Akintomide, Oluwagbemiga Oluwole Ayoola, Tuoyo Omasan Mene-Afejuku, Oluwadare Ogunlade, Oluyomi Oluseun Okunola, Adekunle Oyeyemi Lawal, Adewale Akinsola
Publikováno v:
Clinical Medicine Insights: Cardiology, Vol 13 (2019)
Background: Cardiovascular disease (CVD) is the leading cause of mortality in patients with chronic kidney disease (CKD). Carotid intima-media thickness (CIMT) is a measure of atherosclerotic vascular disease and considered a comprehensive picture of
Externí odkaz:
https://doaj.org/article/72b631c6c06e45b69480c16f7a45d20b
Publikováno v:
Saudi Journal of Kidney Diseases and Transplantation, Vol 23, Iss 6, Pp 1315-1319 (2012)
The morbidity and mortality from acute kidney injury (AKI) have remained relatively high over the last six decades. The triad of infections, nephrotoxins and obstetric complications are still major causes of acute kidney injury in the tropics. This r
Externí odkaz:
https://doaj.org/article/d2ce7f9af1b649458f00006e332076be
Autor:
Adeseye Abiodun Akintunde, Oluyomi Oluseun Okunola, Rotimi Oluyombo, Yussuf Olatunji Oladosu, Oladimeji George Opadijo
Publikováno v:
The Pan African Medical Journal, Vol 11, Iss 75 (2012)
BACKGROUND: Obstructive sleep apnoea (OSA) syndrome is a common disorder in the community. Association between hypertension and sleep apnoea and /or snoring has been described. The Berlin questionnaire is a validated instrument that is used to identi
Externí odkaz:
https://doaj.org/article/21547afcf95d4a6dad88996a4f8228eb
Autor:
Ashwini K. Banala, Martin H. Moore, Rana Rais, Barbara S. Slusher, Rachel D. Slack, Amy Hauck Newman, Caitlin Burzynski, Jeffrey R. Deschamps, Oluyomi M. Okunola-Bakare, Thomas M. Keck, Alessandro Bonifazi
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:4000-4012
The dopamine D3 receptor (D3R) is a target of pharmacotherapeutic interest in a variety of neurological disorders including schizophrenia, Parkinson's disease, restless leg syndrome, and drug addiction. A common molecular template used in the develop
Autor:
Zheng-Xiong Xi, Yi He, Eliot L. Gardner, Xiao-Fei Wang, Oluyomi M. Okunola-Bakare, Hong-Ju Yang, Rachel D. Slack, Jun-Tao Gao, Guo-Hua Bi, Amy Hauck Newman
Publikováno v:
Neuropsychopharmacology. 40:1762-1771
(±)-Modafinil (MOD) is used clinically for the treatment of sleep disorders and has been investigated as a potential medication for the treatment of psychostimulant addiction. However, the therapeutic efficacy of (±)-MOD for addiction is inconclusi
Autor:
Jonathan L. Katz, Claus J. Loland, Lei Shi, Theresa A. Kopajtic, Jianjing Cao, Amy Hauck Newman, Oluyomi M. Okunola-Bakare
Publikováno v:
Journal of Medicinal Chemistry
2-[(Diphenylmethyl)sulfinyl]acetamide (modafinil, (±)-1) is a unique dopamine uptake inhibitor that binds the dopamine transporter (DAT) differently than cocaine and may have potential for the treatment of psychostimulant abuse. To further investiga
Autor:
Jonathan L. Katz, Jianjing Cao, Oluyomi M. Okunola, Thomas E. Prisinzano, Matthew Shook, Theresa A. Kopajtic, Amy Hauck Newman
Publikováno v:
ACS Medicinal Chemistry Letters. 2:48-52
A series of modafinil (1) analogues were synthesized wherein (1) para-halo-substitutents were added to the aryl rings, (2) the sulfoxide function was removed, and (3) the primary amide group was replaced with secondary and tertiary amides and amines
Publikováno v:
Supramolecular Chemistry. 20:169-190
Synthetic receptors have been developed for anions such as chloride, phosphate, sulphate and carboxylate. Development of selective receptors for nitrate has, however, been more difficult. Theoretical calculations show that a six-coordinate geometry i