Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Oluwatosin Oluwadare"'
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-33 (2024)
Abstract Background Chromosome is one of the most fundamental part of cell biology where DNA holds the hierarchical information. DNA compacts its size by forming loops, and these regions house various protein particles, including CTCF, SMC3, H3 histo
Externí odkaz:
https://doaj.org/article/6233f5d7fe1643608fb9a6397f28ffd7
Autor:
David Vadnais, Oluwatosin Oluwadare
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 3, Pp 2549-2560 (2023)
Understanding the three-dimensional (3D) structure of chromatin is invaluable for researching how it functions. One way to gather this information is the chromosome conformation capture (3C) technique and its follow-up technique Hi-C. Here, we presen
Externí odkaz:
https://doaj.org/article/6111fe1452c94bd6a6fc784200d63594
Autor:
Victor Akpokiro, H. M. A. Mohit Chowdhury, Samuel Olowofila, Raisa Nusrat, Oluwatosin Oluwadare
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3210-3223 (2023)
The identification of splice site, or segments of an RNA gene where noncoding and coding sequences are connected in the 5′ and 3′ directions, is an essential post-transcriptional step for the annotation of functional genes and is required for the
Externí odkaz:
https://doaj.org/article/57dc1f97d0d844f99dc37329bcdc985f
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 812-836 (2023)
Chromosome conformation capture (3 C) is a method of measuring chromosome topology in terms of loci interaction. The Hi-C method is a derivative of 3 C that allows for genome-wide quantification of chromosome interaction. From such interaction data,
Externí odkaz:
https://doaj.org/article/3b11ef7187724a1290d9231a8f661f37
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background Chromosome conformation capture and its derivatives have provided substantial genetic data for understanding how chromatin self-organizes. These techniques have identified regions of high intrasequence interactions called topologi
Externí odkaz:
https://doaj.org/article/53181b113acd43659cc747f93876b1b3
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-22 (2022)
Abstract Background Identifying splice site regions is an important step in the genomic DNA sequencing pipelines of biomedical and pharmaceutical research. Within this research purview, efficient and accurate splice site detection is highly desirable
Externí odkaz:
https://doaj.org/article/16db6c1223af4cbea8e73392185feddb
Publikováno v:
BioData Mining, Vol 15, Iss 1, Pp 1-26 (2022)
Abstract Background The three-dimensional (3D) structure of chromatin has a massive effect on its function. Because of this, it is desirable to have an understanding of the 3D structural organization of chromatin. To gain greater insight into the spa
Externí odkaz:
https://doaj.org/article/b0404641441d4fd8923826f1e5db8fc8
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Advances in the study of chromosome conformation capture technologies, such as Hi-C technique - capable of capturing chromosomal interactions in a genome-wide scale - have led to the development of three-dimensional chromosome and genome str
Externí odkaz:
https://doaj.org/article/9b71814c26a5418f9c3340730a1303ec
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-17 (2018)
Abstract Background The development of chromosomal conformation capture techniques, particularly, the Hi-C technique, has made the analysis and study of the spatial conformation of a genome an important topic in bioinformatics and computational biolo
Externí odkaz:
https://doaj.org/article/090e6a1dc9a94eef92a32f7f3227ffbb
Autor:
Oluwatosin Oluwadare, Jianlin Cheng
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background With the development of chromosomal conformation capturing techniques, particularly, the Hi-C technique, the study of the spatial conformation of a genome is becoming an important topic in bioinformatics and computational biology.
Externí odkaz:
https://doaj.org/article/b3817693d0e3451594641234a4ec0602