Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Oluwatobi Adewumi Adeyemo"'
Publikováno v:
Medical Sciences, Vol 3, Iss 3, Pp 78-92 (2015)
Cyclophosphamide (CP), a bifunctional alkylating agent used in chemotherapy has been reported to induce organ toxicity mediated by generation of reactive oxygen species and oxidative stress. Gallic acid (GA), a phenolic substance, is a natural antiox
Externí odkaz:
https://doaj.org/article/feae73c689bd4d99887bb9c84fce9a6e
Autor:
Ebenezer Tunde Olayinka, Ayokanmi Ore, Oluwatobi Adewumi Adeyemo, Olaniyi Solomon Ola, Olaoluwa Oluwaseun Olotu, Roseline Chinonye Echebiri
Publikováno v:
Antioxidants, Vol 4, Iss 2, Pp 304-321 (2015)
Procarbazine (PCZ) (indicated in Hodgkin’s disease), is an alkylating agent known to generate free radicals in vivo, while Quercetin (QCT) is a flavonoid antioxidant with proven free radical scavenging capacity. This study investigated the protecti
Externí odkaz:
https://doaj.org/article/b3a3a4ad22a4427f93d1c1ae792dcfe0
Publikováno v:
Journal of Xenobiotics, Vol 6, Iss 1 (2016)
We investigated the protective effect of gallic acid (GA) against methotrexate (MTX)-induced hepatotoxicity and nephrotoxicity. Male Wistar rats were randomized into five groups (n = 6/group): I, control; II, MTX-treated for seven days; III, pre-trea
Externí odkaz:
https://doaj.org/article/bead7e1d0d9546f49809c381f04a725d
Publikováno v:
Medicines, Vol 4, Iss 4, p 78 (2017)
Background: It has been postulated that during liver and kidney damage there is a decreased in the antioxidant status associated with a simultaneous increase in the reactive oxygen species and lipid peroxidation. In consonant with this, Capecitabine,
Externí odkaz:
https://doaj.org/article/f752dcf9dfa94915a66e527d3c95ab4b
Autor:
Ebenezer Tunde Olayinka, Oluwatobi Adewumi Adeyemo, V.U. Ogbuji, O.O. Olotu, Ayokanmi Ore, Olaniyi Solomon Ola
Publikováno v:
Ife Journal of Science. 23:115-122
Bicalutamide (BCT) is a potent anti-androgen chemotherapeutic drug indicated for prostate cancer. However, BCT is known to cause oxidative stress and impairment of male reproductive function. Whereas Morin (MOR), a flavonoid has been found to be a po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd1b4bce99ca0501686fdf88437fe7a1
https://doi.org/10.4314/ijs.v23i1.11
https://doi.org/10.4314/ijs.v23i1.11
Publikováno v:
Egyptian Journal of Basic and Applied Sciences. 8:293-301
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ff1a4ae009de169f6a33d4e5cdbe380
https://doi.org/10.1080/2314808x.2021.1983746
https://doi.org/10.1080/2314808x.2021.1983746
Publikováno v:
British Journal of Pharmaceutical Research. 6:293-305
Aim: Gatifloxacin (GTX) - an 8 - methoxy fluoroq uinolone antibacterial agent has been considered very effective in the treatment of respiratory and urinary tract infections. This study investigates the toxic potentials of GTX in Wistar rats. Methodo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfac400e72cff18bde12c3608840decf
https://doi.org/10.9734/bjpr/2015/16210
https://doi.org/10.9734/bjpr/2015/16210
Publikováno v:
Chemotherapy Research and Practice
One major challenge with the use of anticancer agents is the phenomenon of drug-induced toxicity. Melphalan (MPLN) is an alkylating anticancer agent, while quercetin (QCT) is an antioxidant. We investigated the protective role of quercetin against MP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f215d9f3428420e256c2ed9d4b6d73
https://doi.org/10.1155/2014/936526
https://doi.org/10.1155/2014/936526
Publikováno v:
Medicines, Vol 4, Iss 4, p 78 (2017)
Medicines
Medicines; Volume 4; Issue 4; Pages: 78
Medicines
Medicines; Volume 4; Issue 4; Pages: 78
Background: It has been postulated that during liver and kidney damage there is a decreased in the antioxidant status associated with a simultaneous increase in the reactive oxygen species and lipid peroxidation. In consonant with this, Capecitabine,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8f05315c37424255ad66048ee2c2f3
https://www.mdpi.com/2305-6320/4/4/78
https://www.mdpi.com/2305-6320/4/4/78
Publikováno v:
Porto Biomedical Journal
Background: Procarbazine (PCZ) is an effective chemotherapeutic drug used in the treatment of lymphoma; however, oxidative stress–mediated testicular toxicity is a major side effect. Recently, therapeutic intervention using flavonoids against oxida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbdcc9dd8ab7e56ff54a88bf1e0209cc
https://doi.org/10.1016/j.pbj.0000000000000028
https://doi.org/10.1016/j.pbj.0000000000000028