Biological activity of a stable 6-aryl-2-benzoyl-pyridine colchicine-binding site inhibitor, 60c, in metastatic, triple-negative breast cancer

Autor: Oluwalana, Damilola, Adeleye, Kelli L., Krutilina, Raisa I., Chen, Hao, Playa, Hilaire, Deng, Shanshan, Parke, Deanna N., Abernathy, John, Middleton, Leona, Cullom, Alexandra, Thalluri, Bhargavi, Ma, Dejian, Meibohm, Bernd, Miller, Duane D., Seagroves, Tiffany N., Li, Wei

Publikováno v: In Cancer Letters 10 August 2024 597

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Sabizabulin, a Potent Orally Bioavailable Colchicine Binding Site Agent, Suppresses HER2+ Breast Cancer and Metastasis.

Autor: Krutilina, Raisa I., Hartman, Kelli L., Oluwalana, Damilola, Playa, Hilaire C., Parke, Deanna N., Chen, Hao, Miller, Duane D., Li, Wei, Seagroves, Tiffany N.

Publikováno v: Cancers; Nov2022, Vol. 14 Issue 21, p5336, 21p

HIF-Dependent CKB Expression Promotes Breast Cancer Metastasis, Whereas Cyclocreatine Therapy Impairs Cellular Invasion and Improves Chemotherapy Efficacy.

Autor: Krutilina RI; Center for Cancer Research, Department of Pathology and Laboratory Medicine, College of Medicine, The University of Tennessee Health Science Center, Cancer Research Building, 19 South Manassas Street, Memphis, TN 38163, USA., Playa H; Center for Cancer Research, Department of Pathology and Laboratory Medicine, College of Medicine, The University of Tennessee Health Science Center, Cancer Research Building, 19 South Manassas Street, Memphis, TN 38163, USA., Brooks DL; Center for Cancer Research, Department of Pathology and Laboratory Medicine, College of Medicine, The University of Tennessee Health Science Center, Cancer Research Building, 19 South Manassas Street, Memphis, TN 38163, USA., Schwab LP; Center for Cancer Research, Department of Pathology and Laboratory Medicine, College of Medicine, The University of Tennessee Health Science Center, Cancer Research Building, 19 South Manassas Street, Memphis, TN 38163, USA., Parke DN; Center for Cancer Research, Department of Pathology and Laboratory Medicine, College of Medicine, The University of Tennessee Health Science Center, Cancer Research Building, 19 South Manassas Street, Memphis, TN 38163, USA., Oluwalana D; Center for Cancer Research, Department of Pathology and Laboratory Medicine, College of Medicine, The University of Tennessee Health Science Center, Cancer Research Building, 19 South Manassas Street, Memphis, TN 38163, USA., Layman DR; School of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38163, USA., Fan M; Center for Cancer Research, Department of Pathology and Laboratory Medicine, College of Medicine, The University of Tennessee Health Science Center, Cancer Research Building, 19 South Manassas Street, Memphis, TN 38163, USA., Johnson DL; Molecular Bioinformatics Core, Office of Research, The University of Tennessee Health Science Center, 71 South Manassas Street, Memphis, TN 38163, USA., Yue J; Center for Cancer Research, Department of Pathology and Laboratory Medicine, College of Medicine, The University of Tennessee Health Science Center, Cancer Research Building, 19 South Manassas Street, Memphis, TN 38163, USA., Smallwood H; Department of Pediatrics, College of Medicine, The University of Tennessee Health Science Center, 71 South Manassas Street, Memphis, TN 38163, USA., Seagroves TN; Center for Cancer Research, Department of Pathology and Laboratory Medicine, College of Medicine, The University of Tennessee Health Science Center, Cancer Research Building, 19 South Manassas Street, Memphis, TN 38163, USA.

Publikováno v: Cancers [Cancers (Basel)] 2021 Dec 22; Vol. 14 (1). Date of Electronic Publication: 2021 Dec 22.