Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Olugbenga A. Adebanjo"'
Publikováno v:
Molecular and Cellular Biology of Bone ISBN: 9780762303908
Publisher Summary This chapter discusses the molecular pharmacology of antiresorptive therapy for osteoporosis. Estrogen is one of the main therapeutic modalities for treating and preventing post-menopausal bone loss. It reduces both cortical and tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8239a966aed4400cf4c348a8cd04f81c
https://ora.ox.ac.uk/objects/uuid:1fee2e50-a60f-494d-ae13-85c8bf7b2546
https://ora.ox.ac.uk/objects/uuid:1fee2e50-a60f-494d-ae13-85c8bf7b2546
Autor:
Xue Bin Wu, Olugbenga A. Adebanjo, Mone Zaidi, Harry C. Blair, Jameel Iqbal, Etsuko Abe, Neeha Zaidi, Xing Yao Wu, Yuanzhen Peng, Li Sun, Solomon Epstein, Baljit S. Moonga
Publikováno v:
Proceedings of the National Academy of Sciences. 102:17130-17135
Two of the most commonly used immunosuppressants, cyclosporine A and tacrolimus (FK506), inhibit the activity of a ubiquitously expressed Ca 2+ /calmodulin-sensitive phosphatase, calcineurin. Because both drugs also cause profound bone loss in humans
Autor:
Frances E. Lund, Mone Zaidi, Peter J. R. Bevis, Christopher L.-H. Huang, Jameel Iqbal, Baljit S. Moonga, Li Sun, Harry C. Blair, Olugbenga A. Adebanjo, Xue-Bin Wu, Etsuko Abe, Svetlana Dolgilevich, Tony Yuen
Publikováno v:
The FASEB Journal. 17:369-375
We have evaluated the role of the ADP-ribosyl cyclase, CD38, in bone remodeling, a process by which the skeleton is being renewed constantly through the coordinated activity of osteoclasts and osteoblasts. CD38 catalyzes the cyclization of its substr
Autor:
Mone Zaidi, Olugbenga A. Adebanjo
Publikováno v:
The Endocrinologist. 10:155-163
Autor:
Mone Zaidi, Samuel Goldstein, Emmanuel M. Awumey, Joshua Epstein, Bali R. Sodam, Antoliy Koval, F. Anthony Lai, Olugbenga A. Adebanjo, Li Sun, Ming-Shyan Huang, Baljit S. Moonga, Gopa Biswas, David A. Lipschitz
Publikováno v:
American Journal of Physiology-Renal Physiology. 278:F576-F584
Herein we demonstrate that replicative cellular senescence in vitro results in sharply reduced inositol 1,4,5-trisphosphate (IP3) receptor levels, reduced mitogen-evoked IP3formation and Ca2+release, and Ca2+store depletion. Human diploid fibroblasts
Autor:
Gopa Biswas, A. James Moser, Toshiya Arakawa, Baljit S. Moonga, Hindupur K. Anandatheerthavarada, Yoshiyuki Hakeda, Li Li Sun, Antoliy Koval, Peter J. R. Bevis, Bruce R. Troen, Solomon Epstein, F. Anthony Lai, Mone Zaidi, Olugbenga A. Adebanjo, Bali R. Sodam, Masayoshi Kumegawa, Susanne Corisdeo
Publikováno v:
Journal of Cell Biology. 146:1161-1172
The multifunctional ADP-ribosyl cyclase, CD38, catalyzes the cyclization of NAD+ to cyclic ADP-ribose (cADPr). The latter gates Ca2+ release through microsomal membrane-resident ryanodine receptors (RyRs). We first cloned and sequenced full-length CD
Publikováno v:
Proceedings of the Association of American Physicians. 111:319-327
The osteoclast is a cell that is unique in its ability to resorb bone and, in doing so, becomes exposed to unusually high millimolar Ca2+ concentrations. It is generally accepted that, during resorption, osteoclasts can "sense" changes in their ambie
Autor:
Mone Zaidi, V.S. Shankar, Baljit S. Moonga, B. Simon, Michael Pazianas, Olugbenga A. Adebanjo, Christopher M.R. Bax
Publikováno v:
Journal of Cellular Physiology. 176:537-544
We report the effects of pulsed electromagnetic fields (PEMFs) on the responsiveness of osteoclasts to cellular, hormonal, and ionic signals. Osteoclasts isolated from neonatal rat long bones were dispersed onto either slices of devitalised cortical
Publikováno v:
American Journal of Physiology-Renal Physiology. 274:F1070-F1077
Extracellular ATP affects a wide variety of cells via purinergic membrane receptors. One class of purinergic receptors, P2X, consists of ATP-gated, calcium-permeable, cation-selective channels. We performed whole cell patch-clamp studies, intracellul
Autor:
Etsuko Abe, Mone Zaidi, Tomoo Yamate, Li Sun, Cedric Minkin, Olugbenga A. Adebanjo, Baljit S. Moonga
Publikováno v:
The Journal of Cell Biology
We describe a physiologically significant mechanism through which interleukin-6 (IL-6) and a rising ambient Ca2+ interact to regulate osteoclastic bone resorption. VOXEL-based confocal microscopy of nonpermeabilized osteoclasts incubated with anti–