Luteolin normalizes blood pressure via its antioxidant activity and down-regulation of renal Angiotensin II receptor and Mineralocorticoid receptor expressions in rats co-exposed to Diclofenac and sodium fluoride

Autor: Temitayo, Ajibade, Akinleye, Akinrinde, Moses, Adetona, Ademola, Oyagbemi, Aduragbenro, Adedapo, Christopher, Larbie, Temidayo, Omobowale, Olufunke, Ola-Davies, Adebowale, Saba, Adeolu, Adedapo, Oluwafemi, Oguntibeju, Momoh, Yakubu

Publikováno v: Nigerian Journal of Physiological Sciences. 37:35-42

This study was designed to investigate the modulatory role of Luteolin (Lut), a flavonoid phytochemical, on haemodynamic parameters and the potential mechanisms involving renal Angiotensin II (AT2R) and Mineralocorticoid (MCR) receptors in renal toxi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212104352febcf87b930b17cb02fea71
https://doi.org/10.54548/njps.v37i1.5

Effects of Telfairia occidentalis and Ipomoea batatas on Biochemical and Antioxidant Assay of African Catfish (Clarias gariepinus)

Autor: Bolaji Tomori, Olanike Adeyemo, Olufunke Ola-Davies, Selim Alarape

Publikováno v: Special Issue. 23

This toxicological study was carried out to determine possible adverse effects of Telfairia occidentalis and Ipomoea batatas leaves in Clarias gariepinus. Ninety-six Clarias gariepinus growers (431.25±6.13 g) randomly distributed into four feeding g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e66faa784dc303febc97d554eab385f
https://doi.org/10.4194/aquast1116

Melatonin ameliorates bisphenol A-induced perturbations of the prostate gland of adult Wistar rats

Autor: Bankole Olusiji Oke, S. G. Olukole, Eunice Olufunke Ola-Davies, Damilare Olaniyi Lanipekun, Samuel Olumide Ajani, Matthew Olugbenga Oyeyemi, O.O. Aina

Publikováno v: Biomedicine & Pharmacotherapy. 105:73-82

Bisphenol A (BPA) is an endocrine disrupting chemical (EDC) that has been demonstrated to induce alterations in reproductive organs while melatonin (ML), an antioxidant, present in plants and animals, is capable of protecting against EDC-induced alte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06cb88b1b01cdeb1795103ea274bbcaa
https://doi.org/10.1016/j.biopha.2018.05.125

Maternal exposure to environmentally relevant doses of bisphenol A causes reproductive dysfunction in F1 adult male rats: protective role of melatonin

Autor: Damilare Olaniyi Lanipekun, S. G. Olukole, Bankole Olusiji Oke, Eunice Olufunke Ola-Davies

Publikováno v: Environmental science and pollution research international. 26(28)

This study investigated the protective effects of melatonin (MLT), a potent antioxidant, in male Wistar rats exposed to environmentally relevant doses of bisphenol A (BPA) in utero. Pregnant Wistar rats were randomly assigned into five groups. Group

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8c0fcabbf5c4f154c1bfec2656cad2
https://pubmed.ncbi.nlm.nih.gov/31388950

Antihypertensive effect of methanol leaf extract of Azadirachta indica is mediated through suppression of renal caspase 3 expressions on N^ω-Nitro-l-arginine methyl ester induced hypertension.

Autor: Omobowale, Temidayo¹ (AUTHOR), Oyagbemi, Ademola² (AUTHOR), Adejumobi, Olumuyiwa¹ (AUTHOR), Ugbor, Fisayo¹ (AUTHOR), Asenuga, Ebunoluwa² (AUTHOR), Ajibade, Temitayo² (AUTHOR), Afolabi, Jeremiah¹ (AUTHOR), Ogunpolu, Blessing¹ (AUTHOR), Falayi, Olufunke³ (AUTHOR), Gbadamos, Idayat⁴ (AUTHOR), Ola-Davies, Olufunke² (AUTHOR), Saba, Adebowale³ (AUTHOR), Ashafa, Anofi⁵ (AUTHOR), Yakubu, Momoh⁶ (AUTHOR), Adedapo, Adeolu⁴ (AUTHOR), Oguntibeju, Oluwafemi⁷ (AUTHOR)

Publikováno v: Pharmacognosy Research. Oct-Dec2020, Vol. 12 Issue 4, p460-465. 6p.