Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Olufsen, Mette S"'
Autor:
Taylor-LaPole, Alyssa M., Paun, L. Mihaela, Lior, Dan, Weigand, Justin D, Puelz, Charles, Olufsen, Mette S.
Hypoplastic left heart syndrome (HLHS) is a congenital heart disease responsible for 23% of infant cardiac deaths each year. HLHS patients are born with an underdeveloped left heart, requiring several surgeries to reconstruct the aorta and create a s
Externí odkaz:
http://arxiv.org/abs/2406.18490
Autor:
Bartolo, Michelle A, Taylor-LaPole, Alyssa M, Gandhi, Darsh, Johnson, Alexandria, Li, Yaqi, Slack, Emma, Stevens, Isaiah, Turner, Zachary, Weigand, Justin D, Puelz, Charles, Husmeier, Dirk, Olufsen, Mette S
Patient-specific computational modeling is a popular, non-invasive method to answer medical questions. Medical images are used to extract geometric domains necessary to create these models, providing a predictive tool for clinicians. However, in vivo
Externí odkaz:
http://arxiv.org/abs/2309.08779
Endotoxin administration is commonly used to study the inflammatory response, and though traditionally given as a bolus injection, it can be administered as a continuous infusion over multiple hours. Several studies hypothesize that the latter better
Externí odkaz:
http://arxiv.org/abs/2308.01495
Autor:
Chambers, Megan, Johnston, Natalie, Livengood, Ian, Spinelli, Miya, Sazdanovic, Radmila, Olufsen, Mette S
Pulmonary hypertension (PH), defined by a mean pulmonary arterial blood pressure above 20 mmHg, is a cardiovascular disease impacting the pulmonary vasculature. PH is accompanied by vascular remodeling, wherein vessels become stiffer, large vessels d
Externí odkaz:
http://arxiv.org/abs/2210.07345
Autor:
Windoloski, Kristen A., Bansgaard, Elisabeth O., Dobreva, Atanaska, Ottesen, Johnny T., Olufsen, Mette S.
This study develops a unified model predicting the whole-body response to endotoxin. We simulate dynamics using differential equations examining the response to a lipopolysaccharide (LPS) injection. The model tracks pro- and anti-inflammatory cytokin
Externí odkaz:
http://arxiv.org/abs/2210.05712
Autor:
Taylor-LaPole, Alyssa M., Colebank, Mitchel J., Weigand, Justin D., Olufsen, Mette S., Puelz, Charles
Patients with hypoplastic left heart syndrome (HLHS) are born with an underdeveloped left heart. They typically receive a sequence of surgeries that result in a single ventricle physiology called the Fontan circulation. While these patients usually s
Externí odkaz:
http://arxiv.org/abs/2205.10206
Autor:
Miranda Hurtado, Martin, Kaempfer, Rafael, Geddes, Justen R., Olufsen, Mette S., Rodriguez-Fernandez, Maria
Publikováno v:
In Mathematical Biosciences November 2024 377
Autor:
Paun, L. Mihaela, Colebank, Mitchel J., Taylor-LaPole, Alyssa, Olufsen, Mette S., Ryan, William, Murray, Iain, Salter, James M., Applebaum, Victor, Dunne, Michael, Hollins, Jake, Kimpton, Louise, Volodina, Victoria, Xiong, Xiaoyu, Husmeier, Dirk
Publikováno v:
In Computer Methods in Applied Mechanics and Engineering 1 October 2024 430
Publikováno v:
In Mathematical Biosciences September 2024 375
Autor:
Haider, Mansoor A., Pearce, Katherine J., Chesler, Naomi C., Hill, Nicholas A., Olufsen, Mette S.
Pulmonary hypertension is a cardiovascular disorder manifested by elevated arterial blood pressure together with vessel wall stiffening and thickening due to alterations in collagen, elastin and smooth muscle cells. Hypoxia-induced (type 3) pulmonary
Externí odkaz:
http://arxiv.org/abs/2202.12711