Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Olubankole Aladesuyi Arogundade"'
Autor:
Olubankole Aladesuyi Arogundade, Sandra Nguyen, Ringo Leung, Danielle Wainio, Maria Rodriguez, John Ravits
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)
Abstract Nucleolar stress has been implicated in the pathology and disease pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) from repeat expansions of GGGGCC in C9orf72 (C9-ALS/FTLD) but not in sporadic
Externí odkaz:
https://doaj.org/article/f3e9576da3cf46fb87cb9dfe86b2a36d
Autor:
Shan Lu, Jiaojiao Hu, Olubankole Aladesuyi Arogundade, Alexander Goginashvili, Sonia Vazquez-Sanchez, Jolene K. Diedrich, Jinge Gu, Jacob Blum, Spencer Oung, Qiaozhen Ye, Haiyang Yu, John Ravits, Cong Liu, John R. Yates, Don W. Cleveland
Publikováno v:
Nat Cell Biol
While acetylated, RNA-binding-deficient TDP-43 reversibly phase separates within nuclei into complex droplets (anisosomes) comprised of TDP-43-containing liquid outer shells and liquid centres of HSP70-family chaperones, cytoplasmic aggregates of TDP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4c7d208833b1d0f855558875917eb5
https://europepmc.org/articles/PMC9872726/
https://europepmc.org/articles/PMC9872726/
Autor:
Sonia Vazquez-Sanchez, Vivian I. Ko, Ruth Chia, Olubankole Aladesuyi Arogundade, Maria J Rodriguez, Don W. Cleveland, John Ravits, Bryan J. Traynor, Sandra Diaz-Garcia
Amyotrophic lateral sclerosis is a progressive fatal neurodegenerative disease caused by loss of motor neurons and characterized neuropathologically in almost all cases by nuclear depletion and cytoplasmic aggregation of TDP-43, a nuclear RNA binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48e956e4a5335ef4de8c9246398357d8
https://doi.org/10.1101/2021.06.03.446017
https://doi.org/10.1101/2021.06.03.446017
Autor:
Ruth Chia, Bryan J. Traynor, John Ravits, Olubankole Aladesuyi Arogundade, Sonia Vazquez-Sanchez, Vivian I. Ko, Don W. Cleveland, Sandra Diaz-Garcia, María Jesús Delgado Rodríguez
Publikováno v:
Acta Neuropathologica
Acta neuropathologica, vol 142, iss 6
Acta neuropathologica, vol 142, iss 6
Amyotrophic lateral sclerosis is a progressive fatal neurodegenerative disease caused by loss of motor neurons and characterized neuropathologically in almost all cases by nuclear depletion and cytoplasmic aggregation of TDP-43, a nuclear RNA-binding
Autor:
John Ravits, Sandra Nguyen, Ringo Leung, Olubankole Aladesuyi Arogundade, María Jesús Delgado Rodríguez, Danielle Wainio
Publikováno v:
Acta neuropathologica communications, vol 9, iss 1
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)
Acta Neuropathologica Communications
Nucleolar stress has been implicated in the pathology and disease pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) from repeat expansions of GGGGCC in C9orf72 (C9-ALS/FTLD) but not in sporadic ALS (SALS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea9ecc3c52a08274444fe3b57326fcc
https://escholarship.org/uc/item/5bq9n5tn
https://escholarship.org/uc/item/5bq9n5tn
Autor:
Daniel Oheb, Pranav Mathkar, Robert H. Baloh, Kevin Taylor, Maria G. Banuelos, Lisa Watson, Ritchie Ho, Irina Khrebtukova, Mariko Kellogg, Olubankole Aladesuyi Arogundade, Michael J. Workman, Jacqueline G. O’Rourke, Valerie Montel, Clive N. Svendsen, Kathryn Wu, Steven Huang, Kevin J. Kim, John Ravits, Sandra Diaz-Garcia
Publikováno v:
Cell systems, vol 12, iss 2
Cell Syst
Cell Syst
Induced pluripotent stem cell- (iPSC) derived neural cultures from amyotrophic lateral sclerosis (ALS) patients can model disease phenotypes. However, heterogeneity arising from genetic and experimental variability limits their utility, impacting rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9d968e1bff5ee806f39c17f0d3a1dc
https://escholarship.org/uc/item/1s686483
https://escholarship.org/uc/item/1s686483
Autor:
Olubankole Aladesuyi Arogundade, Nguyen, Sandra, Leung, Ringo, Wainio, Danielle, Rodriguez, Maria, Ravits, John
Additional file 3. Figure S3: Analysis of nuclear and nucleolar abnormalities in a sub-sample of spinal motor neurons. a–e Stratification of immunofluorescence data. a Distribution of cytoplasmic area in a sub-sample of control, C9-ALS and SALS alp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df14c7bbf28e8a3eb5288183e51743b
Autor:
Olubankole Aladesuyi Arogundade, Nguyen, Sandra, Leung, Ringo, Wainio, Danielle, Rodriguez, Maria, Ravits, John
Additional file 2. Figure S2: Random sampling of spinal motor neurons for statistical analysis. a Number of spinal motor neurons quantified from each patient. b–g Random sampling of neurons for analyzing difference in nucleolar area (b, c), nuclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02884fbea341a3fe97cf3f44f9503bb8
Autor:
Olubankole Aladesuyi Arogundade, Nguyen, Sandra, Leung, Ringo, Wainio, Danielle, Rodriguez, Maria, Ravits, John
Additional file 6. Table S1: Nucleolar Antisense (AS) RNA Foci Stratification. Table S2 TDP-43 Stratification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee02c100ab0711046b9ad17f5252db7
Autor:
Olubankole Aladesuyi Arogundade, Nguyen, Sandra, Leung, Ringo, Wainio, Danielle, Rodriguez, Maria, Ravits, John
Additional file 4. Figure S4: Sexual dimorphism in spinal motor neuron nucleolar and nuclear area is abolished in C9-ALS and SALS. a, b Nucleolar (a) and nuclear area (b) are significantly larger in male control cases compared to females but are simi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600aaf9e09b39723159cb807777b8bb0